Unraveling the Host–Virus Interplay in Viral Infection: Molecular Mechanisms and Therapeutic Horizons

Dear Colleagues,

Viruses present formidable challenges to global health, including rapid mutation rates, zoonotic spillovers, and the potential for pandemics that overwhelm healthcare systems, as seen with recent emerging virus outbreaks like COVID-19 and Mpox. These threats underscore the urgent needs for scientific advancements in understanding host–virus interplay at molecular levels, developing robust antiviral defenses, and translating clinical insights into innovative therapies. By fostering interdisciplinary research in virology and medicine, we can enhance preparedness, improve diagnostics, and create effective vaccines to mitigate future risks. This issue delves into the dynamic host–virus interplay in viral infection across molecular aspects, examining cellular interactions, antiviral defenses, pathogenic processes, and their implications for disease management. We welcome original research, reviews, and perspectives that bridge fundamental molecular biology with clinical outcomes, including novel therapeutic and molecular virus surveillance strategies to address viral challenges. Our aim is to foster interdisciplinary contributions to advance virology and improve health outcomes.

This Special Issue is supervised by Dr. Agustín Valenzuela-Fernández and assisted by Dr. Romina Cabrera-Rodríguez (Universidad de La Laguna).

Dr. Agustín Valenzuela-Fernández
Guest Editor

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