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Diagnostics
Special Issues
Advances in Echocardiography Diagnostics
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Advances in Echocardiography Diagnostics

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 674

Special Issue Editor

Dr. Hatem Soliman Aboumarie

E-Mail Website
Guest Editor
1. Department of Cardiothoracic Intensive Care and Mechanical Circulatory Support, Harefield Hospital, Royal Brompton and Harefield Hospitals, London, UK
2. School of Cardiovascular, Metabolic Sciences and Medicine, King’s College London, London, UK
Interests: critical care echocardiography; point of care ultrasound; mechanical circulatory support; heart and lung transplantation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue highlights the latest breakthroughs in echocardiography, covering cutting-edge techniques such as 3D/4D imaging, strain echocardiography, contrast-enhanced ultrasound, and AI-powered diagnostics. Experts explore innovations in valvular disease assessment, myocardial function analysis, and point-of-care applications. This Issue also addresses challenges in standardization, emerging technologies, and future directions in cardiovascular imaging. Aimed at clinicians, researchers, and sonographers, it provides valuable insights to enhance diagnostic accuracy, patient care, and clinical outcomes. Join us in advancing the field of echocardiography through groundbreaking research and clinical advancements.

Dr. Hatem Soliman Aboumarie
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • echocardiography innovations
  • cardiac imaging advancements
  • strain echocardiography
  • 3D/4D cardiac ultrasound

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Published Papers (1 paper)

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Research

16 pages, 1966 KB  
Article
Left Ventricular and Left Atrial Strain Characteristics in Patients with Familial Mediterranean Fever Receiving Long-Term Colchicine Therapy
by Hüseyin Durak, Mustafa Çetin, Nadir Emlek, Ali Gökhan Özyıldız, Hakan Duman, Elif Ergül, Ahmet Özsipahi, Barış Dindar and Osman Cüre
Diagnostics 2026, 16(2), 296; https://doi.org/10.3390/diagnostics16020296 - 16 Jan 2026
Viewed by 427
Abstract
Background: Familial Mediterranean fever (FMF) is a chronic autoinflammatory disorder characterized by sustained systemic inflammation that may affect cardiac structure and function. Colchicine is the cornerstone of FMF therapy and has cardiovascular benefits in inflammatory settings. Methods: This cross-sectional study enrolled 106 participants: [...] Read more.
Background: Familial Mediterranean fever (FMF) is a chronic autoinflammatory disorder characterized by sustained systemic inflammation that may affect cardiac structure and function. Colchicine is the cornerstone of FMF therapy and has cardiovascular benefits in inflammatory settings. Methods: This cross-sectional study enrolled 106 participants: 53 patients with FMF receiving long-term colchicine therapy and 53 age- and sex-matched controls. Participants underwent transthoracic echocardiography with speckle-tracking imaging. Conventional parameters and strain-derived indices of the left ventricular (LV) and left atrial (LA) function were assessed. Correlation analyses and multivariable linear regression models were used to evaluate the association between FMF presence and cardiac strain parameters. Results: The LV ejection fractions were comparable between the groups. The FMF group showed thinner ventricular walls and larger chamber dimensions than the control group. Patients with FMF exhibited higher LA reservoir strain, while conduit and contractile atrial contributions were reduced, as shown by lower passive and active emptying fractions and reduced LA ejection fraction. LA volumes and stiffness indices were lower in the FMF group, indicating smaller and more compliant atrial structures. Left ventricular global longitudinal strain (LVGLS) was more negative in patients with FMF, indicating preserved LV longitudinal systolic function. FMF was independently associated with LVGLS and LA strain parameters after adjusting for cardiovascular risk factors. Conclusions: In patients with FMF receiving long-term colchicine therapy, cardiac strain imaging showed preserved LV longitudinal function and distinct LA mechanics with preserved reservoir strain but reduced conduit and contractile function. Strain echocardiography may provide insights into cardiac involvement in well-controlled FMF, although prospective studies are needed to clarify the clinical significance of these findings. Full article
(This article belongs to the Special Issue Advances in Echocardiography Diagnostics)
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