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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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3rd Edition: AI/ML-Based Medical Image Processing and Analysis

edited by

Ghazanfar Latif

and

Jaafar Alghazo

submission deadline 30 Jun 2026 | 29 articles | Viewed by 38218 | Submission Open

Keywords: machine learning; artificial intelligence; medical imaging; medical diagnosis; medical; magnetic resonance imaging (MRI); CT scan; X-ray; computer tomography; imaging techniques; medical conditions; convolutional neural networks; deep learning; transfer learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Insights into the Diagnosis of Gynecological Diseases

edited by

Dah Ching Ding

submission deadline 30 Jun 2026 | 5 articles | Viewed by 35041 | Submission Open

Keywords: gynecological diseases; precision medicine; molecular diagnostics; artificial intelligence; biomarkers; next-generation sequencing; imaging technologies; big data

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Prognosis of Gynecological and Obstetric Diseases

edited by

Giuseppe Gullo

and Valentina Billone

submission deadline 30 Jun 2026 | 11 articles | Viewed by 19313 | Submission Open

Keywords: diagnosis; prognosis; gynecological and obstetric diseases; markers; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Adverse Drug Reactions in Precision Medicine and Big Data

edited by

Elena Ramírez

submission deadline 30 Jun 2026 | 1 articles | Viewed by 17338 | Submission Open

Keywords: adverse drug reactions; pharmacovigilance; drug safety; risk factors; causality assessment; big data; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Pathology and Diagnosis of Gynecologic Diseases, 3rd Edition

edited by

Cinzia Giacometti

and Mariateresa Mirandola

submission deadline 30 Jun 2026 | 7 articles | Viewed by 17217 | Submission Open

Keywords: gynecologic pathology; breast pathology; placental pathology; diagnostic pitfalls; differential diagnosis; molecular biology; immunohistochemistry; in situ hybridization

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advancements in Diagnostic Tools in the Emergency Department (ED): A Possible Help to Avoid Overcrowding

edited by

Jacopo M. Legramante

submission deadline 30 Jun 2026 | 3 articles | Viewed by 16035 | Submission Open

Keywords: critical care; emergency medicine; diagnostics

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Ultrasound Diagnosis and Guided Intervention of Musculoskeletal/Neuromuscular Pathology, Second Edition

edited by

Ke-Vin Chang

submission deadline 30 Jun 2026 | 6 articles | Viewed by 15861 | Submission Open

Keywords: diagnosis; ultrasound; pain; muscle; tendon; nerve; rehabiltation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovations in Imaging for Radiation Oncology

edited by

Sara Haseli

and Arash Azhideh

submission deadline 30 Jun 2026 | 2 articles | Viewed by 14318 | Submission Open

Keywords: radiation oncology; diagnostic imaging; artificial intelligence; radiomics; tumor detection; molecular imaging; treatment planning; radiogenomics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathology and Diagnosis of Neurological Disorders, 2nd Edition

edited by James Yip

submission deadline 30 Jun 2026 | 4 articles | Viewed by 12957 | Submission Open

Keywords: stroke; CNS tumors; neurodegenerative diseases; traumatic brain injury

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Clinical Decision Support—2nd Edition

edited by

Qingqing Mao

submission deadline 30 Jun 2026 | 6 articles | Viewed by 12090 | Submission Open

Keywords: artificial intelligence; machine learning; clinical decision support; predictive modeling; patient monitoring; diagnostic support; treatment recommendation; safety and privacy

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advancements in Interventional Radiology Techniques in Vascular and Extravascular Diseases

edited by

Francesco Giurazza

and

Fabio Corvino

submission deadline 30 Jun 2026 | 9 articles | Viewed by 12074 | Submission Open

Keywords: embolization; radial; oncology; radioembolization; ablation; chemoembolization

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Echocardiography

edited by Grazia Canciello

submission deadline 30 Jun 2026 | 3 articles | Viewed by 11749 | Submission Open

Keywords: echocardiography; cardiovascular imaging; three-dimensional echocardiography; strain imaging; TrueVue imaging; cardiac function assessment; clinical applications; non-invasive cardiology; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Ultrasound Diagnosis in Maternal Fetal Medicine Practice

edited by

Kwok-yin Leung

Ka-Wang Cheung

and Lau Wai-Lam

submission deadline 30 Jun 2026 | 5 articles | Viewed by 11638 | Submission Open

Keywords: obstetric ultrasound; placenta; fetal abnormalities; color doppler

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnosis and Management in Anesthesia and Pain Medicine

edited by Jamal Hasoon

submission deadline 30 Jun 2026 | 7 articles | Viewed by 9309 | Submission Open

Keywords: anesthesia and pain medicine; interventional pain management; regional anesthesia; neuromodulation; treatment outcomes; clinical practice patterns; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Heart Failure: Clinical Diagnosis, Treatment, and Prognosis

edited by

Massimo Mapelli

and Irene Mattavelli

submission deadline 30 Jun 2026 | 4 articles | Viewed by 7364 | Submission Open

Keywords: heart failure; clinical diagnosis; treatment advances; precision medicine; exercise evaluation; CPET

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Laboratory Analysis and Diagnostics

edited by Ivana Lapić

submission deadline 30 Jun 2026 | 7 articles | Viewed by 7350 | Submission Open

Keywords: laboratory analysis; diagnostics; analytical techniques; diagnostic methods

(This special issue belongs to the Section Clinical Laboratory Medicine)

21st Century Point-of-Care, Near-Patient and Critical Care Testing—2nd Edition

edited by

Gerald J. Kost

submission deadline 30 Jun 2026 | 7 articles | Viewed by 6796 | Submission Open

Keywords: point-of-care testing; infectious diseases; early detection; emergency management; disaster readiness; prehospital diagnosis; health promotion; public health resilience

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

PET/CT Imaging in Oncology: Clinical Advances and Perspectives

edited by

Francesco Lanfranchi

submission deadline 30 Jun 2026 | 4 articles | Viewed by 6681 | Submission Open

Keywords: PET/CT imaging; molecular imaging; oncology; cancer diagnosis; precision oncology; treatment planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Gynecological Oncology: Advanced Diagnosis and Management in 2025

edited by

Zoard T. Krasznai

and

Rudolf Lampé

submission deadline 30 Jun 2026 | 3 articles | Viewed by 6604 | Submission Open

Keywords: gynecology; oncology; endometrial cancer; ovarian cancer; cervical cancer; diagnosis; staging; surgical methods; standardization of surgery; treatment; innovation; precision medicine; artificial intelligence; machine learning

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Ultrasound in Renal Diseases: A Useful Tool for Diagnostics and Therapy

edited by

Caterina Carollo

submission deadline 30 Jun 2026 | 4 articles | Viewed by 6578 | Submission Open

Keywords: kidney; nephrology; ultrasounds; radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Neurodiagnostics in Public Health: Cognitive Decline, Mental Health, and Emerging Technologies

edited by

Evgenia Gkintoni

and

Apostolos Vantarakis

submission deadline 30 Jun 2026 | 4 articles | Viewed by 6106 | Submission Open

Keywords: neurocognitive disorders; dementia; mild cognitive impairment (MCI); neuropsychiatric diseases; biomarkers; imaging; artificial intelligence; digital diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Personalized Medicine

edited by Otilia Țica

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5910 | Submission Open

Keywords: cardiovascular disease; biomarkers; precision medicine; diagnostics; heart failure

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Applications of Artificial Intelligence in Orthopedics

edited by Zhonghai Li

submission deadline 30 Jun 2026 | 4 articles | Viewed by 4803 | Submission Open

Keywords: artificial intelligence; orthopedics; medical diagnosis; image analysis; predictive modeling

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Alzheimer’s Disease Diagnosis—2nd Edition

edited by

Mohammad Shahadat Hossain

submission deadline 30 Jun 2026 | 5 articles | Viewed by 4572 | Submission Open

Keywords: Alzheimer’ s disease; artificial intelligence; machine learning; explainable AI; expert systems; computer vision; deep learning; diagnosis; cognition; brain informatics; neurodegenerative disorder

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Early Diagnosis of Sepsis: Current Status and Challenges

edited by

Andrea Piccioni

and

Gloria Rozzi

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4361 | Submission Open

Keywords: sepsis; early diagnosis of sepsis; biomarkers; sepsis mortality; serum presepsin; SOFA score

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advanced Neuroimaging Analysis: From Data to Diagnosis

edited by

Igor Petrušić

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3860 | Submission Open

Keywords: neuroimaging analysis ; multimodal integration ; multimodal imaging ; biomarkers ; diagnostic pipelines ; clinical translation ; neurological disorders

(This special issue belongs to the Section Medical Imaging and Theranostics)

Contemporary Spine Diagnostics and Management

edited by

Gun Choi

submission deadline 30 Jun 2026 | 4 articles | Viewed by 3790 | Submission Open

Keywords: spine diagnostics; spine management; AI-assisted diagnostics; minimally invasive interventions; molecular biomarkers; imaging techniques; telemedicine; multidisciplinary care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Genomics for Prenatal Diagnosis

edited by Wing-Cheong Leung and

Ye Cao

submission deadline 30 Jun 2026 | 4 articles | Viewed by 3767 | Submission Open

Keywords: prenatal diagnosis; genetics; genomics; NIPT; WES; WGS; CRISPR; epigenetics; expanded carrier screening

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Fetal Doppler Assessment: From Basic Research to Clinical Practice

edited by Luís Guedes-Martins

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3734 | Submission Open

Keywords: fetal Doppler; fetal growth restriction; preeclampsia; fetal-placental hemodynamics; fetal death; placental abruption; placental circulation; fetal cerebral circulation; fetal hepatic circulation; fetal heart function

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Plastic Surgery: Diagnosis, Management and Prognosis

edited by

Konstantinos Seretis

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3659 | Submission Open

Keywords: plastic surgery; breast reconstruction; skin graft; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Photon-Counting CT in Clinical Application

edited by Philipp Gruschwitz

submission deadline 30 Jun 2026 | 4 articles | Viewed by 3655 | Submission Open

Keywords: protocol development and optimization; spectral imaging; tissue characterization; lesion classification; benefits of special resolution; radiation dose optimization; contrast agent

(This special issue belongs to the Section Medical Imaging and Theranostics)

Infective Endocarditis in Cardiac Prosthesis and Devices

edited by José Alberto San Román-Calvar and Javier López-Díaz

submission deadline 30 Jun 2026 | 4 articles | Viewed by 3402 | Submission Open

Keywords: infective endocarditis; valvular surgical prosthesis; TAVRs; cardiac electronic implantable devices; left ventricular assist devices

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

State of the Art in the Diagnosis and Management of Endocrine Tumors

edited by Milan D. Jovanović

submission deadline 30 Jun 2026 | 4 articles | Viewed by 3272 | Submission Open

Keywords: thyroid; parathyroid; adrenal; neuroendocrine tumors

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic Imaging for Cerebrovascular Diseases

edited by Hiroaki Neki

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3084 | Submission Open

Keywords: cerebrovascular diseases; diagnostic imaging; perfusion imaging; hemodynamic assessment; radiomics; artificial intelligence (AI); imaging biomarkers; follow-up protocols

(This special issue belongs to the Section Medical Imaging and Theranostics)

Generative AI and Digital Twins in Diagnostics

edited by

Sean Benson

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2698 | Submission Open

Keywords: digital twins; electronic health record; generative AI; personalized medicine; clinical practice; simulation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Management of Colorectal Diseases, 2nd Edition

edited by

Filippo Carannante

and

Guglielmo Niccolò Piozzi

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2516 | Submission Open

Keywords: colorectal diseases; markers; diagnosis; prognosis; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Microbial Infections and Critical Care Medicine: Diagnosis and Management, 2nd Edition

edited by Eleni K. Mouloudi,

Serafeim Chrysovalantis Kotoulas

and Eleni Massa

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2436 | Submission Open

Keywords: microbial infections; superbugs; antimicrobial resistance; multi-drug resistance; critical care; diagnosis; management

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Novel Diagnostic Approaches and Treatment of Angina and Myocardial Ischemia

edited by

Marcin Kozuch

and

Emil Julian Dąbrowski

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2428 | Submission Open

Keywords: ischemia; angina; chronic coronary syndromes; ANOCA; INOCA; CMD; CFR; microcirculation; scintigraphy; CMR

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Technologies in Oral Medicine: From Molecular Pathology to Clinical Practice—2nd Edition

edited by

Stefano Gennai

Marco Nisi

and

Rossana Izzetti

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2398 | Submission Open

Keywords: oral medicine; molecular pathology; clinical dentistry; periodontics; orthodontics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Horizons in Digestive Endoscopic Diagnosis

edited by Barchi Alberto

submission deadline 30 Jun 2026 | Viewed by 2359 | Submission Open

Keywords: diagnostic endoscopy ; novel imaging ; artificial intelligence (AI) ; precision medicine ; early detection ; gastrointestinal diseases ; minimally invasive ; clinical decision-making

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Horizons in Multiple Myeloma Diagnosis and Therapy

edited by Ulrike Dapunt

submission deadline 30 Jun 2026 | Viewed by 2142 | Submission Open

Keywords: multiple myeloma diagnosis and therapy; imaging techniques; biomarkers; genetic and epigenomic profiling; supportive cancer care; exercise therapy; nutrition; pain management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Biomarkers for Clinical Diagnosis and Prognosis

edited by

Ji Hyun Park

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1962 | Submission Open

Keywords: biomarkers; personalized medicine; molecular signatures; prognosis predictive diagnostics; prognostic diagnostics; genetic biomarkers; blood analysis; liquid biopsy; tumor marker

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Retinopathy—2nd Edition

edited by

Joanna Gołȩbiewska

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1916 | Submission Open

Keywords: diabetic retinopathy; hypertensive retinopathy; inherited retinal diseases; imaging; OCT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Imaging in Oral Diseases

edited by Xavier Roselló-LLabres and

José López López

submission deadline 30 Jun 2026 | 3 articles | Viewed by 1817 | Submission Open

Keywords: CBCT 3D maxillofacial imaging; virtual diagnostic simulation; social media pathology image sharing; oral disease diagnostic algorithms; AI-driven oral pathology detection; dental radiographic caries analysis; digital oral lesion segmentation; cross-disciplinary imaging workflows; tele-radiology collaboration platforms; salivary gland scintigraphy applications

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Imaging in Urologic Disorders

edited by Matteo Droghetti

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1802 | Submission Open

Keywords: diagnostic imaging; urologic disorders; ultrasound; CT; MRI; PET; hybrid imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Optimization of Clinical Imaging: From Diagnosis to Prognosis, 2nd Edition

edited by

Georg Böning

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1799 | Submission Open

Keywords: clinical imaging; medical image analysis; imaging management; computed tomography (CT); magnetic resonance imaging (MRI)

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Nuclear Medicine and Molecular Imaging

edited by

Gabriele Masselli

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1788 | Submission Open

Keywords: cancer; cardiovascular imaging; neurodegenerative conditions; computed tomography; molecular imaging; neuroimaging; positron emission tomography (PET); single-photon emission computed tomography (SPECT); nuclear medicine; molecular imaging; theranostics; response evaluation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostics in Focus: Accelerating Access for Priority Diseases in Africa

edited by Rosanna Peeling,

Debi Boeras

and Nicaise Ndembi

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1745 | Submission Open

Keywords: diagnostics; epidemic-prone diseases; outbreak preparedness and response

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Medical Image Processing

edited by Zhiwei Wang

submission deadline 30 Jun 2026 | 3 articles | Viewed by 1563 | Submission Open

Keywords: medical image processing; foundation models; multimodal learning; computer-aided diagnosis; image segmentation and registration; generative AI; clinical decision support; representation learning; explainable and trustworthy AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnosis and Management of Autoimmune Diseases

edited by

Micol Romano

and

Dimitri Poddighe

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1457 | Submission Open

Keywords: autoimmunity; autoinflammatory diseases; rheumatology; innovative and biological therapies; comorbidity; immune-mediated manifestations

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

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