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Diagnostics
Special Issues
Advances in Diagnostic Imaging for Cerebrovascular Diseases
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Advances in Diagnostic Imaging for Cerebrovascular Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 2235

Special Issue Editor

Dr. Hiroaki Neki

E-Mail Website
Guest Editor
Department of Neurosurgery, Hamamatsu University School of Medicine, University Hospital, Hamamatsu, Japan
Interests: stroke; neuroendovascular surgery; development of medical devices

Special Issue Information

Dear Colleagues,

Recent advances in neurointerventional and surgical therapies have transformed the management of cerebrovascular diseases, and yet optimal strategies for diagnostic imaging—including evaluation after endovascular or surgical intervention—are still being developed. This Special Issue, “Advances in Diagnostic Imaging for Cerebrovascular Diseases”, will focus on emerging imaging technologies and analytical approaches to enhance diagnostic assessment across the entire disease course, from initial diagnosis to post-treatment follow-up. Topics of interest include perfusion and hemodynamic imaging, radiomics and AI-based image analysis, and imaging biomarkers reflecting vascular remodeling, inflammation, and treatment durability. By integrating advanced diagnostic imaging into clinical outcomes, this Special Issue will promote a deeper understanding of cerebrovascular pathophysiology and support the standardization of imaging protocols. We welcome the submission of original research, technical innovations, and comprehensive reviews that advance evidence-based diagnostic approaches in cerebrovascular diseases.

Dr. Hiroaki Neki
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cerebrovascular diseases
  • diagnostic imaging
  • perfusion imaging
  • hemodynamic assessment
  • radiomics
  • artificial intelligence (AI)
  • imaging biomarkers
  • follow-up protocols

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Published Papers (1 paper)

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12 pages, 2264 KB  
Case Report
Branch-Critical Clipping of a Ruptured Carotid–Posterior Communicating Aneurysm with Fetal PCA Configuration
by Catalina-Ioana Tataru, Cosmin Pantu, Alexandru Breazu, Felix-Mircea Brehar, Matei Serban, Razvan-Adrian Covache-Busuioc, Corneliu Toader, Octavian Munteanu, Mugurel Petrinel Radoi and Adrian Vasile Dumitru
Diagnostics 2026, 16(2), 307; https://doi.org/10.3390/diagnostics16020307 - 18 Jan 2026
Viewed by 419
Abstract
Background/Objectives: Aneurysmal subarachnoid hemorrhage (aSAH) involves a sudden onset of a perfusion-pressure injury from the initial insult combined with a secondary injury phase produced by delayed cerebral ischemia, cerebrospinal fluid circulation disturbances, and generalized instability of the patient’s physiological state. The situation may [...] Read more.
Background/Objectives: Aneurysmal subarachnoid hemorrhage (aSAH) involves a sudden onset of a perfusion-pressure injury from the initial insult combined with a secondary injury phase produced by delayed cerebral ischemia, cerebrospinal fluid circulation disturbances, and generalized instability of the patient’s physiological state. The situation may be further complicated when there has been rupture of the aneurysm at the site of the carotid–posterior communicating (PCom) artery junction that occurs in conjunction with a fetal configuration of the posterior cerebral artery (fPCA), thereby making definitive treatment dependent on preserving the critical nature of the branches of the posterior circulation since the aneurysm’s neck plane coincides with the dominant posterior circulation conduit. Case Presentation: A 65-year-old female patient who was obese (Grade III BMI = 42), had chronic bronchial asthma, and arterial hypertension experienced a “thunderclap” type of headache in the right retro-orbital area followed by a syncopal episode and developed acute confusion with agitation. Upon admission to the hospital, her Glasgow Coma Scale (GCS) was 13, her FOUR score was 15, her Montreal Cognitive Assessment (MoCA) score was 12/30, her Hunt–Hess grade was 3, WFNS grade 2, and Fisher grade 4 SAH with intraventricular extension. Digital subtraction angiography (DSA) and three-dimensional rotational angiography revealed a posteriorly directed right carotid communicating aneurysm that had a relatively compact neck (approximately 2.5 mm) and sac size of approximately 7.7 × 6.6 mm, with the fPCA originating at the neck plane. Microsurgical treatment was performed with junction-preserving reconstruction with skull base refinement, temporary occlusion of the internal carotid artery for a few minutes, placement of clips reconstructing the carotid–PCom interface, and micro-Doppler verification of patent vessel. Postoperatively, the blood pressure was kept within the range of 110–130 mmHg with nimodipine and closely monitored. The neurological recovery was sequential (GCS of 15 by POD 2; MoCA of 22 by POD 5). By POD 5 CT scan, the clip remained positioned in a stable fashion without evidence of infarct, hemorrhage, or hydrocephalus; at three months she was neurologically intact (mRS 0; Barthel 100; MoCA 28/30), and CTA confirmed persistent exclusion of the aneurysm and preservation of fPCA flow. Conclusions: In cases where the ruptured aneurysm is located at the carotid communicating junction with the PCom artery in a configuration of the posterior cerebral artery that is described as fetal, clip treatment should be viewed as a form of branch-preserving junction reconstruction of the carotid–PCom junction supported by adherence to controlled postoperative physiology and close ppostoperativesurveillance. Full article
(This article belongs to the Special Issue Advances in Diagnostic Imaging for Cerebrovascular Diseases)
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