Multiple Myeloma: From Molecular Mechanism to Diagnosis and Therapy

Dear Colleagues,

Multiple myeloma is a plasma cell disorder that represents the second most common form of blood cancer. Multiple myeloma is still considered an incurable pathology, but survival has nearly doubled in recent years due to the use of novel drugs and novel therapeutic strategies. Knowledge about the molecular mechanisms and pathogenesis of multiple myeloma has a key role in the diagnosis and treatment of this disease. Moreover, laboratories play an essential role in the diagnosis and management of subjects affected by multiple myeloma. Different chemistry and molecular assays are performed to monitor the patient’s progress, response to treatment, and relapse. The use of protein and urine electrophoresis, serum-free light chains, and cytogenetic testing are important in the identification of subjects with multiple myeloma; that is, the presence of a monoclonal immunoglobulin. In this Special Issue, we welcome submissions covering all aspects of multiple myeloma, ranging from molecular mechanisms, diagnostic tools, biomarker development, and novel therapies.

Potential topics will include the following:

• The molecular mechanisms involved;
• Immunopathogenesis of the disease;
• Laboratory tests and methods;
• Diagnosis;
• Treatments

Dr. Jari Intra
Guest Editor

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