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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Rehabilitation Opportunities in Cancer Survivorship

edited by

Marie Carmen Valenza

and Alejandro Heredia-Ciuro

submission deadline 8 May 2026 | 3 articles | Viewed by 5854 | Submission Open

Keywords: cancer; rehabilitation; sequelae; disability; impairment

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Hepatocellular Carcinoma Progression and Metastasis

edited by

Ching-Sheng Hsu

submission deadline 10 May 2026 | 1 articles | Viewed by 1900 | Submission Open

Keywords: hepatocellular carcinoma; tumor progression; metastasis; liver cancer; angiogenesis; epithelial– mesenchymal transition; tumor microenvironment; molecular pathways; biomarkers; targeted therapy; systemic therapy

(This special issue belongs to the Section Cancer Metastasis)

Genetics in Hematological Malignancies

edited by

Monika Lejman

submission deadline 10 May 2026 | 1 articles | Viewed by 1336 | Submission Open

Keywords: hematological malignancies; genomic alterations; personalized medicine; next-generation sequencing; epigenetics; biomarkers; leukemia; lymphoma; myeloma; genetic profiling

(This special issue belongs to the Section Molecular Cancer Biology)

Artificial Intelligence for Network-Based Oncomarker Discovery and Cancer Prediction

edited by Oleg Blyuss

submission deadline 10 May 2026 | 2 articles | Viewed by 1087 | Submission Open

Keywords: artificial intelligence (AI); network-based biomarkers; graph neural networks (GNNs); multi-omic integration; cancer prediction; oncomarker discovery; prognostic and predictive biomarkers

(This special issue belongs to the Section Cancer Informatics and Big Data)

Targeted Therapy of Pediatric Cancer (2nd Edition)

edited by

Günther H.S. Richter

submission deadline 10 May 2026 | Viewed by 522 | Submission Open

Keywords: leukemia; lymphoma; pediatric solid malignancies; targeted therapy; biomarker discovery; actionable mutations; drug vulnerabilities; combination therapy; immunotherapeutic approaches; preclinical studies

(This special issue belongs to the Section Pediatric Oncology)

Oncoproteins in Cancers: Transcriptional Regulation, Signaling and Targeted Therapy

edited by

Ravindran Caspa Gokulan

and

Francis Ali-Osman

submission deadline 11 May 2026 | Viewed by 198 | Submission Open

Keywords: oncoproteins; targeted therapy; oncogenic signaling pathways; tumor microenvironment; oxidative stress and cancer; tumorigenesis; cancer chemoprevention

(This special issue belongs to the Section Molecular Cancer Biology)

Molecular and Clinical Challenges in Metastatic and Oligometastatic Genitourinary Cancers

edited by Marlon Perera

submission deadline 11 May 2026 | Submission Open

Keywords: genitourinary cancers; oligometastatic disease; metastasis-directed therapy; precision oncology; molecular profiling; biomarkers; liquid biopsy; tumour microenvironment; imaging and radiomics

(This special issue belongs to the Section Cancer Metastasis)

Systemic Treatment for Breast Cancer

edited by

Luigia Stefania Stucci

submission deadline 12 May 2026 | Viewed by 16 | Submission Open

Keywords: breast cancer; biomarker; treatment; management

(This special issue belongs to the Section Cancer Therapy)

Infectious Agents and Cancer in Children and Adolescents

edited by

Emmanouel Hatzipantelis

and Eleni Tsotridou

submission deadline 15 May 2026 | 4 articles | Viewed by 9663 | Submission Open

Keywords: infectious agents; immune system; tumor development; immunological memory; oncolytic viruses

(This special issue belongs to the Section Infectious Agents and Cancer)

Endoscopic Advances in Gastrointestinal Oncology

edited by Eduardo Rodrigues-Pinto

submission deadline 15 May 2026 | 1 articles | Viewed by 4962 | Submission Open

Keywords: endoscopic oncology; endoscopic screening; endoscopic resection; endoscopic palliation; staging

(This special issue belongs to the Section Cancer Therapy)

Recent Advance in Colorectal Cancer Liver Metastases

edited by

Peter Metrakos

and Jennifer Kalil

submission deadline 15 May 2026 | 3 articles | Viewed by 4477 | Submission Open

Keywords: colorectal cancer liver metastases; histological growth patterns; chemotherapy optimization; liver regeneration; future liver remnant; liquid biopsy; treatment resistance

(This special issue belongs to the Section Cancer Metastasis)

Breast Cancer Screening: Global Practices and Future Directions

edited by Rudolf Morant

submission deadline 15 May 2026 | 1 articles | Viewed by 832 | Submission Open

Keywords: mammography screening; organized screening programs; tomosynthesis; 2D mammography; artificial intelligence; personalized screening

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Integrative Histopathological–Molecular–Computational Analysis of Primary Brain Tumors

edited by

Adriana Olar

submission deadline 15 May 2026 | Viewed by 549 | Submission Open

Keywords: brain tumor histopathology; neuropathology; molecular pathology; digital pathology; artificial intelligence; bioinformatics; computational pathology; deep learning

(This special issue belongs to the Section Cancer Informatics and Big Data)

Minimally Invasive Gastric Cancer Surgery

edited by

Gian Luca Baiocchi

, Simone Giacopuzzi and Felix Berlth

submission deadline 15 May 2026 | Viewed by 374 | Submission Open

Keywords: gastric cancer; laparoscopy; robotic surgery; fluorescence; minimally invasive surgery; lymphadenectomy

(This special issue belongs to the Section Cancer Therapy)

Targeted Therapy for Liver Metastases

edited by

Gianluca Rompianesi

and

Jacopo Lanari

submission deadline 15 May 2026 | Viewed by 282 | Submission Open

Keywords: targeted therapy; liver metastases; biological therapy

(This special issue belongs to the Section Cancer Therapy)

Gene Editing and Delivery for Cancer Therapy (2nd Edition)

edited by

Yong Teng

and

Yamin Li

submission deadline 15 May 2026 | Viewed by 148 | Submission Open

Keywords: gene therapy; gene editing; gene delivery; oncolytic viruses; nanomaterial; peptides; nanostructures; exosomes; translational science

(This special issue belongs to the Section Cancer Therapy)

Molecular and Genetic Diagnosis and Targeted Therapy of Myeloproliferative Neoplasms (2nd Edition)

edited by

Jinming Song

and

Ling Zhang

submission deadline 15 May 2026 | Viewed by 136 | Submission Open

Keywords: myeloproliferative neoplasm; chronic myeloid leukemia; polycythemia vera; essential thrombocythemia; primary myelofibrosis; MPN; CML; PMF; PV; ET

(This special issue belongs to the Section Molecular Cancer Biology)

Mass Spectrometry and Cancers

edited by

Rita Casadonte

and

Kristina Schwamborn

submission deadline 15 May 2026 | Viewed by 112 | Submission Open

Keywords: cancer; biomolecular; mass spectrometry

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Locoregional Therapies for Gastrointestinal Cancer Metastases

edited by

Mazin Al-Kasspooles

submission deadline 15 May 2026 | Viewed by 80 | Submission Open

Keywords: gastrointestinal cancer metastases; locoregional therapies; interventional radiology; endoscopy; radiation therapy; invasive operations; cytoreductive surgery (CRS); intraperitoneal chemotherapy (IP); heated intraperitoneal chemotherapy (HIPEC); tumor debulking; stereotactic body radiation therapy (SBRT); selective internal radiation therapy (SIRT)

(This special issue belongs to the Section Methods and Technologies Development)

The Surgical Management of Colorectal Cancer

edited by Gyung-mo Son

submission deadline 20 May 2026 | 10 articles | Viewed by 24334 | Submission Open

Keywords: colorectal cancer; surgical management; minimally invasive surgery; laparoscopic surgery; robotic surgery; single port surgery; emergency surgery; image-guided surgery; enhanced recovery after surgery (ERAS); systemic metastasis in colorectal cancer (involving the liver; lung; peritoneum; etc.)

(This special issue belongs to the Section Cancer Therapy)

Improving the Quality of Life in Patients with Gynecological Cancer

edited by Vasilios Pergialiotis

submission deadline 20 May 2026 | 1 articles | Viewed by 3794 | Submission Open

Keywords: gynecologic oncology; minimal invasive surgery; ovarian cancer; ERAS protocol; perioperative care; immunonutrition; cervical cancer

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

From Bench to Bedside: Novel Molecular Targets and Therapeutic Strategies in AML

edited by Matteo Molica

submission deadline 20 May 2026 | 1 articles | Viewed by 1122 | Submission Open

Keywords: acute myeloid leukemia; targeted therapy; precision medicine; FLT3 inhibitors; IDH1/2 inhibitors; BCL2 inhibition; menin inhibitors; drug resistance; minimal residual disease; combination therapy

(This special issue belongs to the Section Cancer Therapy)

How to Properly Diagnose and Treat Immune-Related Adverse Events During Immunotherapy in Patients with Cancer: Discussion Between Specialists (2nd Edition)

edited by

Angioletta Lasagna

and

Paolo Sacchi

submission deadline 20 May 2026 | Viewed by 94 | Submission Open

Keywords: ICIs; immune-related adverse effects (irAEs); infectious complications; immune reconstitution; inflammatory syndrome (IRIS); microbiota; vaccines; molecular mimicry

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in Endometrial Cancer Prevention, Early Diagnosis and Treatment

edited by

Sarah J. Kitson

submission deadline 20 May 2026 | Viewed by 85 | Submission Open

Keywords: endometrial cancer; gynaecologic oncology; surgery; prevention; early diagnosis; advanced therapy; molecular classification; biomarkers

(This special issue belongs to the Section Cancer Therapy)

Advances in T-Cell Redirecting Therapy in Plasma Cell Neoplasms

edited by Henry Chi Hang Fung and Asya Varshavsky

submission deadline 20 May 2026 | Viewed by 83 | Submission Open

Keywords: multiple myeloma; CAR-T; T-cell engager; novel targets; sequencing

(This special issue belongs to the Section Cancer Therapy)

Viral Oncogenes and Their Role in Cancer Pathogenesis

edited by

Ronen Borenstein

and Yosef Sabo

submission deadline 21 May 2026 | 3 articles | Viewed by 6697 | Submission Open

Keywords: viral oncogenes; cancer pathogenesis; cellular regulation; tumorigenesis mechanisms; antiviral and anticancer strategies

(This special issue belongs to the Section Infectious Agents and Cancer)

Non-Melanoma Skin Cancer: A Growing Problem in the Elderly Population

edited by Jolanta Jaworek and Dariusz Kowalczyk

submission deadline 21 May 2026 | Viewed by 27 | Submission Open

Keywords: NMSC; pathomechanism of NMSC; NMSC and gut and/or skin microbiota; NMSC treatment; NMSC diagnosis

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Next-Generation Automation in Radiation Oncology: Innovations in Planning, Informatics, and Clinical Workflow

edited by

Ozgur Ates

and Jared Becksfort

submission deadline 22 May 2026 | Viewed by 5 | Submission Open

Keywords: radiation oncology; radiotherapy automation; autosegmentation; rapid automated treatment planning; zero-click quality assurance; fast clinical workflow; artificial intelligence; machine learning; clinical decision support; radiomics; image-guided radiotherapy; adaptive radiation therapy; human-in-the-loop automation; healthcare informatics

(This special issue belongs to the Section Methods and Technologies Development)

Inhibitors in Thyroid Carcinoma (2nd Edition)

edited by

Alessandro Antonelli

submission deadline 24 May 2026 | Viewed by 124 | Submission Open

Keywords: thyroid carcinoma; immune checkpoint inhibitors; tyrosine kinase inhibitors; sorafenib; lenvatinib

(This special issue belongs to the Section Tumor Microenvironment)

Study on Acute Myeloid Leukemia

edited by Olga K. Weinberg

submission deadline 25 May 2026 | 3 articles | Viewed by 5893 | Submission Open

Keywords: acute myeloid leukemia (AML); cancer treatment; genetic

(This special issue belongs to the Section Cancer Therapy)

Clinical Advances and State-of-the-Art Management in Genitourinary Cancers

edited by

Jad Chahoud

and Adnan Fazili

submission deadline 25 May 2026 | 2 articles | Viewed by 4569 | Submission Open

Keywords: genitourinary malignancies; tumor– immune microenvironment (TIME); tumor biology; genomic characterization; targeted drug therapy; immunotherapy

(This special issue belongs to the Section Clinical Research of Cancer)

Colorectal Cancer: Risk Factors and Underlying Mechanisms

edited by David Achaintre

submission deadline 25 May 2026 | Viewed by 153 | Submission Open

Keywords: colorectal cancer; diet; environmental factors; microbiome; inflammation

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Molecular Mechanisms of Breast Cancer Treatment-Related Side Effects and Precision Interventions

edited by

Jennifer Hu

submission deadline 26 May 2026 | Viewed by 110 | Submission Open

Keywords: breast cancer; treatment-related side effects; biomarker; precision interventions

(This special issue belongs to the Section Cancer Therapy)

Primary and Recurrent Gynecological Cancer: Epidemiology, Management and New Therapies

edited by Nithya Ratnavelu and Ioannis Biliatis

submission deadline 28 May 2026 | 3 articles | Viewed by 4511 | Submission Open

Keywords: ovarian cancer; endometrial cancer; cervical cancer; vulva cancer; vaginal cancer; gynecological cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

New Approaches in Radiotherapy for Cancer

edited by Dandan Zheng, Alexander Podgorsak and Olga Maria Dona Lemus

submission deadline 30 May 2026 | 21 articles | Viewed by 75451 | Submission Open

Keywords: adaptive radiotherapy; FLASH; artificial intelligence; SFRT; particle therapy; proton therapy; SRS; SBRT; HDR; 3D printing; immuno-radiotherapy; radiogenmics

(This special issue belongs to the Section Cancer Therapy)

AI-Driven Oncology: Advancing Cancer Detection, Diagnosis, and Personalized Treatment

edited by

Mohamed Shehata

and

Fatma M. Talaat

submission deadline 30 May 2026 | 4 articles | Viewed by 3155 | Submission Open

Keywords: cancer detection and diagnosis; AI in oncology; explainable AI (XAI); precision oncology; medical imaging; prognostic biomarkers; clinical decision support systems

(This special issue belongs to the Section Methods and Technologies Development)

Endoscopic Management of Pancreatic Neoplasms (2nd Edition)

edited by

Nam Quoc Nguyen

submission deadline 30 May 2026 | 2 articles | Viewed by 3146 | Submission Open

Keywords: pancreatic cancer; pancreatic neoplasm; endoscopic retrograde cholangiopancreatography; endoscopic ultrasound; fine needle aspiration/biopsy; local treatment; biliary stent; biliary drainage; contrast enhancement

(This special issue belongs to the Section Methods and Technologies Development)

Current Advances in Management of Neuroendocrine Neoplasms

edited by Ashley Kieran Clift and

Andrea Frilling

submission deadline 30 May 2026 | 1 articles | Viewed by 1511 | Submission Open

Keywords: neuroendocrine tumours; epidemiology; clinical prediction models; machine learning; personalised medicine; novel biomarkers; diagnostics; treatment; artificial intelligence

(This special issue belongs to the Section Cancer Therapy)

Skin Cancer Prevention: Strategies, Challenges and Future Directions

edited by Véronique del Marmol, Mariano Suppa, Ana-Maria Forsea and Alexander Stratigos

submission deadline 30 May 2026 | 2 articles | Viewed by 1005 | Submission Open

Keywords: skin cancer prevention; photoprotection; early detection; screening; epidemiology; public health; behavioral interventions; sun exposure; artificial intelligence; risk factors

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Radiomics in Head and Neck Cancer Care (2nd Edition)

edited by

Aurora Mirabile

submission deadline 30 May 2026 | 1 articles | Viewed by 932 | Submission Open

Keywords: radiomics; personalized therapeutic approach; radiology; improving outcome; head and neck cancer; imaging biomarkers; artificial intelligence

(This special issue belongs to the Section Methods and Technologies Development)

Liquid Biopsy for Lung Cancer Treatment (2nd Edition)

edited by

Maria Palmieri

and Frullanti Elisa

submission deadline 30 May 2026 | Viewed by 291 | Submission Open

Keywords: cancer; lung cancer; new strategies; liquid biopsy; CTC; exosomes; Cf-NA; DdPCR; NGS

(This special issue belongs to the Section Cancer Biomarkers)

Advances in the Diagnosis and Treatment of Prostate Cancer: From Biomarkers to Precision Surgery

edited by Stamatios N. Katsimperis and

Lazaros Tzelves

submission deadline 30 May 2026 | 1 articles | Viewed by 178 | Submission Open

Keywords: prostate cancer; precision medicine; molecular biomarkers; risk stratification; robotic surgery; artificial intelligence; genomics; personalized treatment; imaging modalities; multidisciplinary approach

(This special issue belongs to the Section Cancer Therapy)

Genetics of Ovarian Cancer (2nd Edition)

edited by

Stergios Boussios

and

Sola Adeleke

submission deadline 30 May 2026 | Viewed by 168 | Submission Open

Keywords: epithelial ovarian cancer; genomics; epigenetics; translational research; biomarkers; DNA damage response; PARP inhibitors

(This special issue belongs to the Section Cancer Pathophysiology)

Updates on Depression Among Cancer Patients (2nd Edition)

edited by Wen-Yu Hu,

Yun-Chen Chang

and

Elsa Vitale

submission deadline 30 May 2026 | Viewed by 137 | Submission Open

Keywords: depression; psychotherapy; oncology nursing

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Blood Stem Cell and Hematological Malignancies (Second Edition)

edited by Dirk Loeffler

submission deadline 30 May 2026 | Viewed by 77 | Submission Open

Keywords: hematopoietic stem cells; hematological malignancies; clonal hematopoiesis; clonal evolution; preleukemia and leukemia; self-renewal and differentiation; asymmetric cell division; cell polarity; therapy resistance; transformation

(This special issue belongs to the Section Molecular Cancer Biology)

Revolutionizing Cancer Treatment: Advances in Radiation Therapy

edited by

Hans Christiansen

submission deadline 30 May 2026 | Viewed by 4 | Submission Open

Keywords: radiation therapy; radiooncology; radiobiology; radiosensitivity; high-precision radiotherapy; stereotactic radiotherapy; particle therapy; FLASH radiotherapy; image-guided radiotherapy (IGRT); radiochemotherapy; radioimmunotherapy; translational research; clinical outcome

(This special issue belongs to the Section Cancer Therapy)

Mechanism of Action of Novel Anticancer Drugs in Cancer Treatment

edited by

Ruifang Liu

submission deadline 30 May 2026 | Submission Open

Keywords: targeted therapy; immunotherapy; tumor-agostic approval; therapy resistence; mechaninsm of action; kinase inhibitor; immune checkpoint inhibitor

(This special issue belongs to the Section Cancer Drug Development)

Integrating Radiomics and Radiotherapy in Cancer Care: Quantitative Imaging and Efficacy Assessment

edited by

Savino Cilla

submission deadline 30 May 2026 | Submission Open

Keywords: radiomics; radiogenomics; radiation oncology; imaging biomarkers; predictive models; machine learning; precision radiotherapy; quantitative imaging

(This special issue belongs to the Section Methods and Technologies Development)

Health Services Research in Cancer Care

edited by

Carmen Martos

and

Francesco Giusti

submission deadline 31 May 2026 | 7 articles | Viewed by 15323 | Submission Open

Keywords: cancer care; cancer care outcomes; cancer care services; cancer costs; treatment; health systems; quality; survival; indicators; health technology assessments

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Cancer Biomarkers—Detection and Evaluation of Response to Therapy

edited by

Giulio Francia

and

Jianying Zhang

submission deadline 31 May 2026 | 5 articles | Viewed by 8577 | Submission Open

Keywords: biomarkers; cancer detection; biomarkers of response to antineoplastic drugs; biomarkers of resistance to chemotherapy; biomarkers for targeted therapies

(This special issue belongs to the Section Cancer Biomarkers)

Displaying special issue 651-700 on page 14 of 24.

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