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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Skin Cancer Prevention: Strategies, Challenges and Future Directions
edited by Véronique del Marmol, Mariano Suppa, Ana-Maria Forsea and Alexander Stratigos
submission deadline 30 May 2026 | 3 articles | Viewed by 2439 | Submission Open
Keywords: skin cancer prevention; photoprotection; early detection; screening; epidemiology; public health; behavioral interventions; sun exposure; artificial intelligence; risk factors
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
New and Future Focused Therapies for Thyroid Cancer
edited by , Poupak Fallahi, Silvia Martina Ferrari and Giusy Elia
submission deadline 30 May 2026 | 1 articles | Viewed by 2089 | Submission Open
Keywords: aggressive differentiated thyroid carcinoma; anaplastic thyroid cancer; tyrosine kinase inhibitors; immunotherapy; personalized medicine
(This special issue belongs to the Section Cancer Therapy)
Current Advances in Management of Neuroendocrine Neoplasms
edited by Ashley Kieran Clift and
submission deadline 30 May 2026 | 1 articles | Viewed by 1797 | Submission Open
Keywords: neuroendocrine tumours; epidemiology; clinical prediction models; machine learning; personalised medicine; novel biomarkers; diagnostics; treatment; artificial intelligence
(This special issue belongs to the Section Cancer Therapy)
Radiomics in Head and Neck Cancer Care (2nd Edition)
edited by
submission deadline 30 May 2026 | 1 articles | Viewed by 1424 | Submission Open
Keywords: radiomics; personalized therapeutic approach; radiology; improving outcome; head and neck cancer; imaging biomarkers; artificial intelligence
(This special issue belongs to the Section Methods and Technologies Development)
Advances in the Diagnosis and Treatment of Prostate Cancer: From Biomarkers to Precision Surgery
edited by Stamatios N. Katsimperis and
submission deadline 30 May 2026 | 1 articles | Viewed by 1044 | Submission Open
Keywords: prostate cancer; precision medicine; molecular biomarkers; risk stratification; robotic surgery; artificial intelligence; genomics; personalized treatment; imaging modalities; multidisciplinary approach
(This special issue belongs to the Section Cancer Therapy)
Minimally Invasive Surgery and Robotic Techniques in GI Cancer Treatment
edited by Luca Milone and Abid Qureshi
submission deadline 30 May 2026 | 1 articles | Viewed by 366 | Submission Open
Keywords: minimally invasive surgery; robotic surgery; gastrointestinal cancer; surgical oncology; laparoscopic surgery; advanced surgical technology; robotic-assisted procedures; AI in robotic surgery
(This special issue belongs to the Section Methods and Technologies Development)
Liquid Biopsy for Lung Cancer Treatment (2nd Edition)
edited by and Frullanti Elisa
submission deadline 30 May 2026 | Viewed by 318 | Submission Open
Keywords: cancer; lung cancer; new strategies; liquid biopsy; CTC; exosomes; Cf-NA; DdPCR; NGS
(This special issue belongs to the Section Cancer Biomarkers)
Genetics of Ovarian Cancer (2nd Edition) submission deadline 30 May 2026 | Viewed by 217 | Submission Open
Keywords: epithelial ovarian cancer; genomics; epigenetics; translational research; biomarkers; DNA damage response; PARP inhibitors
(This special issue belongs to the Section Cancer Pathophysiology)
Updates on Depression Among Cancer Patients (2nd Edition)
edited by Wen-Yu Hu, and
submission deadline 30 May 2026 | Viewed by 172 | Submission Open
Keywords: depression; psychotherapy; oncology nursing
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Blood Stem Cell and Hematological Malignancies (Second Edition)
edited by Dirk Loeffler
submission deadline 30 May 2026 | Viewed by 101 | Submission Open
Keywords: hematopoietic stem cells; hematological malignancies; clonal hematopoiesis; clonal evolution; preleukemia and leukemia; self-renewal and differentiation; asymmetric cell division; cell polarity; therapy resistance; transformation
(This special issue belongs to the Section Molecular Cancer Biology)
Revolutionizing Cancer Treatment: Advances in Radiation Therapy
edited by
submission deadline 30 May 2026 | Viewed by 77 | Submission Open
Keywords: radiation therapy; radiooncology; radiobiology; radiosensitivity; high-precision radiotherapy; stereotactic radiotherapy; particle therapy; FLASH radiotherapy; image-guided radiotherapy (IGRT); radiochemotherapy; radioimmunotherapy; translational research; clinical outcome
(This special issue belongs to the Section Cancer Therapy)
Integrating Radiomics and Radiotherapy in Cancer Care: Quantitative Imaging and Efficacy Assessment
edited by
submission deadline 30 May 2026 | Viewed by 77 | Submission Open
Keywords: radiomics; radiogenomics; radiation oncology; imaging biomarkers; predictive models; machine learning; precision radiotherapy; quantitative imaging
(This special issue belongs to the Section Methods and Technologies Development)
Mechanism of Action of Novel Anticancer Drugs in Cancer Treatment
edited by
submission deadline 30 May 2026 | Viewed by 40 | Submission Open
Keywords: targeted therapy; immunotherapy; tumor-agostic approval; therapy resistence; mechaninsm of action; kinase inhibitor; immune checkpoint inhibitor
(This special issue belongs to the Section Cancer Drug Development)
Pathology of Renal Tumors
edited by and Anna Caliò
submission deadline 30 May 2026 | Viewed by 40 | Submission Open
Keywords: renal cell tumors; diagnosis; prognosis; metabolomics; genomics; molecular; immunohistochemistry; histopathology
(This special issue belongs to the Section Cancer Pathophysiology)
Health Services Research in Cancer Care submission deadline 31 May 2026 | 7 articles | Viewed by 16958 | Submission Open
Keywords: cancer care; cancer care outcomes; cancer care services; cancer costs; treatment; health systems; quality; survival; indicators; health technology assessments
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Developments in the Management of Gastrointestinal Malignancies (2nd Edition)
edited by Zachary J. Brown
submission deadline 31 May 2026 | 5 articles | Viewed by 12112 | Submission Open
Keywords: gastrointestinal malignancies; multimodal therapy; chemotherapy; radiotherapy; immunotherapy; localized and metastatic
(This special issue belongs to the Section Cancer Therapy)
Cancer Biomarkers—Detection and Evaluation of Response to Therapy submission deadline 31 May 2026 | 5 articles | Viewed by 9438 | Submission Open
Keywords: biomarkers; cancer detection; biomarkers of response to antineoplastic drugs; biomarkers of resistance to chemotherapy; biomarkers for targeted therapies
(This special issue belongs to the Section Cancer Biomarkers)
Gut Microbiome, Diet and Cancer Risk
edited by
submission deadline 31 May 2026 | 4 articles | Viewed by 8402 | Submission Open
Keywords: gut microbiome; cancer; diet; dysbiosis; immunity; dietary fiber; probiotic; short-chain fatty acids (SCFAs)
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Exploring the Interplay of Glioblastoma Angiogenesis, ROS, and Tumor Microenvironment: Advancements in Combination Therapy and Bioinformatics Approaches
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 8059 | Submission Open
Keywords: glioblastoma; angiogenesis; reactive oxygen species (ROS); hypoxia-inducible factors (HIFs); radiotherapy (RT); bioactive natural compounds; tumor microenvironment (TME); cancer immunotherapy; combination therapy; autophagy; apoptosis; in silico and network pharmacology; bioinformatics
(This special issue belongs to the Section Cancer Metastasis)
Advances in Proton Therapy for Head and Neck Cancer: Techniques, Outcomes and Planning Variations
edited by Jun Zhou
submission deadline 31 May 2026 | 3 articles | Viewed by 7761 | Submission Open
Keywords: proton head and neck cancer therapy; protons vs. photons for head and neck cancer treatment; adaptive proton therapy; robustness in proton head and neck cancer therapy; online vs. offline adaptation in proton head and neck cancer therapy
(This special issue belongs to the Section Cancer Therapy)
Local Management of Breast Cancer: The Evolving Relationship Between Radiotherapy and Surgery
edited by Shengyang Peter Wu
submission deadline 31 May 2026 | 2 articles | Viewed by 7641 | Submission Open
Keywords: biomarker-guided personalized breast treatment; targeted axillary dissection; neoadjuvant therapy; local therapy; radiotherapy reduction; ultrahypofractionated partial breast irradiation
(This special issue belongs to the Section Cancer Therapy)
Advances in Treatment of Uveal Melanoma submission deadline 31 May 2026 | 2 articles | Viewed by 6368 | Submission Open
Keywords: uveal melanoma; distant metastases; treatment modalities
(This special issue belongs to the Section Cancer Therapy)
Updates on Thyroid Cancer
edited by and
submission deadline 31 May 2026 | 4 articles | Viewed by 6259 | Submission Open
Keywords: thyroid cancer; surgery; updates; diagnosis; molecular biology; personalized medicine; artificial intelligence; novel therapeutic strategies; patient outcomes
(This special issue belongs to the Section Cancer Therapy)
Prostate Cancer and Inflammation
edited by Takuji Hayashi
submission deadline 31 May 2026 | 2 articles | Viewed by 4121 | Submission Open
Keywords: prostate cancer; inflammation; immune cells; cytokine; chemokine; anti-inflammatory agents; diet; microbiome
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Molecular Pathways in Cancers (2nd Edition) submission deadline 31 May 2026 | 2 articles | Viewed by 3997 | Submission Open
Keywords: highly prevalent cancers; tumor microenvironment; oncogenesis; progression; novel targeted therapy; prognosis
(This special issue belongs to the Section Molecular Cancer Biology)
MicroRNA in Cancer: From Molecular Mechanisms to Therapeutic Applications
edited by Girish Shukla and
submission deadline 31 May 2026 | 4 articles | Viewed by 3330 | Submission Open
Keywords: microRNA (miRNA) therapeutics; cancer biomarkers; oncogenic and tumor-suppressive miRNAs; miRNA delivery systems; precision oncology
(This special issue belongs to the Section Cancer Biomarkers)
The Role of Circulating Tumor Cells in Colorectal Cancer
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 3230 | Submission Open
Keywords: circulating tumor cells (CTC); colorectal cancer (CRC); liquid biopsy; biomarkers; tumor progression; personalized medicine; molecular profiling; metastasis; diagnostic techniques; prognostic evaluation
(This special issue belongs to the Section Cancer Biomarkers)
Focus on Focal Therapy for Prostate Cancer
edited by Abhinav Sidana and Samuel Tremblay
submission deadline 31 May 2026 | 2 articles | Viewed by 3063 | Submission Open
Keywords: focal therapy; prostate cancer treatment; image-guided therapy; oncological outcomes; functional outcome; patient selection; surveillance
(This special issue belongs to the Section Cancer Therapy)
Advances in Targeted Therapies in Cancer (2nd Edition)
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 2797 | Submission Open
Keywords: targeted therapy; cancer; antibody therapy; small molecule inhibitor; RNAi therapy; cell-based therapy
(This special issue belongs to the Section Cancer Therapy)
Advances in Cell and Gene Therapy in Tumors: From Bench to Bedside
edited by Shuhang Wang
submission deadline 31 May 2026 | 1 articles | Viewed by 2450 | Submission Open
Keywords: cell therapy; gene therapy; genetically engineered cells; cancer treatment; clinical trials; pre-clinical study
(This special issue belongs to the Section Cancer Therapy)
Quality of Life in Patients with Brain Tumors
edited by Priya U. Kumthekar, Akanksha Sharma and Margaret Johnson
submission deadline 31 May 2026 | 1 articles | Viewed by 2049 | Submission Open
Keywords: quality of life; palliative care; patient reported outcomes; survivorship; caregiver distress; symptom management
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Therapeutic Optimization of Anti-Tumor Drugs Based on Pharmacokinetics
edited by Paula Fresco and Joaquim António Faria Monteiro
submission deadline 31 May 2026 | 1 articles | Viewed by 1968 | Submission Open
Keywords: anti-cancer drugs; pharmacokinetics; therapeutic drug monitoring; cancer; populational pharmacokinetics models
(This special issue belongs to the Section Cancer Drug Development)
Radiotherapy for the Management of Brain Metastases
edited by Alla Gabriella Wernicke
submission deadline 31 May 2026 | 1 articles | Viewed by 1742 | Submission Open
Keywords: brain metastases; molecular profiles; imaging advancements; systemic treatment options; radiotherapeutic techniques; primary irradiation; re-irradiation; cutting-edge clinical research
(This special issue belongs to the Section Cancer Metastasis)
Primary Central Nervous System Lymphoma: A Challenging Disease
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 1689 | Submission Open
Keywords: primary central nervous system lymphoma (PCNSL); diffuse large B cell lymphoma (DLBCL); advanced imaging; novel therapies; prognostic markers
(This special issue belongs to the Section Clinical Research of Cancer)
Clinical and Translational Research of Urological Cancer submission deadline 31 May 2026 | 2 articles | Viewed by 1554 | Submission Open
Keywords: urological cancer; bladder cancer; surgery; conservative treatment; immunotherapy; radical cystectomy; artifical intelligence
(This special issue belongs to the Section Clinical Research of Cancer)
Advances in Neoadjuvant Chemotherapy and Radiotherapy for Breast Cancer: Surgical Impact and Clinical Outcomes
edited by Amparo García-Tejedor
submission deadline 31 May 2026 | 1 articles | Viewed by 1441 | Submission Open
Keywords: neoadjuvant chemotherapy; radiotherapy; breast cancer; surgical outcomes; tumor downstaging; personalized therapy; breast-conserving surgery; mastectomy; clinical outcomes
(This special issue belongs to the Section Cancer Therapy)
Survivorship and Quality of Life in Endometrial Cancer
edited by George Koukourakis, , Georgios Angelopoulos and Anthi Miliadou
submission deadline 31 May 2026 | 1 articles | Viewed by 1321 | Submission Open
Keywords: endometrial cancer; quality of life; survivorship
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Current Status and Prospects of Multimodal Treatment for Upper Gastrointestinal Cancer
edited by Koichi Okamoto
submission deadline 31 May 2026 | 1 articles | Viewed by 1236 | Submission Open
Keywords: upper gastrointestinal cancer; esophageal cancer; gastric cancer; esophagogastric junction cancer; chemotherapy; oncology; endoscopic resection; minimally invasive surgery; robotic surgery
(This special issue belongs to the Section Cancer Therapy)
The Impact of Minimally Invasive Surgery on Gynecologic Cancers
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 1206 | Submission Open
Keywords: minimally invasive surgery; robotic-assisted surgery; gynecologic malignancy; laparoscopy
(This special issue belongs to the Section Cancer Therapy)
Nano-Targeting of Cancer
edited by Thomas Ming Swi Chang OC MD CM PhD DSc FRCPC FRSC FCAHS
submission deadline 31 May 2026 | 1 articles | Viewed by 967 | Submission Open
Keywords: drug delivery; artificial intelligence; targeted delivery; nanorobotics; prodrug activation; intracellular action; liposome; PEGylation; nanoparticles; nanocapsules; nanoartificial cells
(This special issue belongs to the Section Cancer Therapy)
Decoding the Dynamic Matrix Complexity in Cancer submission deadline 31 May 2026 | Viewed by 526 | Submission Open
Keywords: extracellular matrix; cancer pathobiology; 3D spheroids/organoids; modeling tumor microenvironment complexity; matrix-based bioscaffolds; matrix remodeling; cell surface matrix mediators and effectors; matrix degrading enzymes; proteoglycans/glycosaminoglycans; collagen; matrix (glyco)proteins; molecular targeting
(This special issue belongs to the Section Tumor Microenvironment)
Multimodality Management of Sarcomas (2nd Edition)
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 444 | Submission Open
Keywords: sarcomas; multimodal; pathology; radiology; surgery; chemotherapy; radiotherapy
(This special issue belongs to the Section Cancer Therapy)
Lymphoid and Myeloid Leukemias—Current Progress in Biology and Treatment
edited by Ewa Robak and
submission deadline 31 May 2026 | Viewed by 430 | Submission Open
Keywords: acute myeloid leukemia; promyelocytic leukemia; myelomonocytic leukemia; chronic lymphocytic leukemia; hairy cell leukemia; prolymphocytic leukemia; large granular lymphocyte leukemia; acute lymphoblastic leukemia
(This special issue belongs to the Section Molecular Cancer Biology)
Advances in Urological Cancer: Innovative Therapies and Biomarkers
edited by Hiroshi Yaegashi
submission deadline 31 May 2026 | 1 articles | Viewed by 372 | Submission Open
Keywords: urological oncology; urothelial cancer; prostate cancer; renal cancer; biomarkers; immunotherapy
Emerging Nanotechnology and Advanced Materials for Cancer Therapy
edited by
submission deadline 31 May 2026 | Viewed by 273 | Submission Open
Keywords: biomaterials; theranostics; cancer therapy; targeted drug delivery; precision oncology
(This special issue belongs to the Section Methods and Technologies Development)
PET/CT in Radiation Oncology
edited by Gurdip Azad and
submission deadline 31 May 2026 | Viewed by 235 | Submission Open
Keywords: PET-CT; radiation oncology; theranostics; artificial intelligence; personalised care; tumour volume delineation; adaptive radiotherapy
(This special issue belongs to the Section Methods and Technologies Development)
Advances in Surgical and Multimodal Treatments of Hepatopancreatobiliary Cancers
edited by , Matteo Serenari and
submission deadline 31 May 2026 | Viewed by 216 | Submission Open
Keywords: pancreatic cancer; liver metastases; hepatocellular carcinoma; cholangiocarcinoma; neuroendocrine tumours; intraductal papillary mucinous neoplasms (IPMN); pancreatic cystic tumours; robotic surgery; laparoscopic surgery; 3D reconstruction; liver hypertrophy
(This special issue belongs to the Section Cancer Therapy)
Advances in High-Grade Serous Ovarian Cancer: New Perspectives Promising Hope for Eradicating a Devastating Disease
edited by
submission deadline 31 May 2026 | Viewed by 210 | Submission Open
Keywords: high-grade serous ovarian cancer; risk factors; prevention; early detection; symptoms; screening; standard of care; platinum resistant ovarian cancer; novel therapeutic approaches; drug repositioning; artificial intelligence; life expectancy; quality of life; and prognosis
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Thermal Analysis and Proteomic Approaches for Biofluid Proteome Profiling in Cancer Diagnostics
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 198 | Submission Open
Keywords: thermal analysis; proteomics; thermal liquid biopsy; differential scanning calorimetry; mass spectrometry; serum proteome; clinical diagnostics; cancer diagnostics; biospecimen
(This special issue belongs to the Section Methods and Technologies Development)
The Future of Cancer Immunotherapy: Biomarkers, Tumor Microenvironment, and Precision Medicine
edited by Aftab Alam
submission deadline 31 May 2026 | Viewed by 177 | Submission Open
Keywords: immunotherapy; genomics; proteomics checkpoint; CAR T cells; predictive biomarkers; resistance mechanisms; combination approaches; tumor microenvironment
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
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