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Thermal Analysis and Proteomic Approaches for Biofluid Proteome Profiling in Cancer Diagnostics

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 1

Special Issue Editor


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Guest Editor
1. UofL Health—Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202, USA
2. Division of Medical Oncology and Hematology, Department of Medicine, University of Louisville, Louisville, KY 40202, USA
Interests: biochemistry; biophysical chemistry; biomolecule structure, stability and interactions; disease proteomics; development of biophysical technologies for medical diagnostics
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Special Issue Information

Dear Colleagues,

Building upon the previous edition, “Differential Scanning Calorimetry and Related Thermal Analysis Techniques as Complementary Approaches for Cancer Diagnosis, Prognosis, Monitoring and Assessment of Treatment Response”, this Special Issue expands the focus to include thermal analysis and proteomics methodologies as complementary approaches to enhance and refine current cancer diagnostics strategies. The featured manuscripts address a broad range of topics, including the use of combined thermal and proteomic profiling to gain new insights into cancer detection and disease characterization; the development of innovative tools—like novel algorithms for more efficient processing of thermal liquid biopsy (TLB) data, a promising adjunct in the diagnostic arsenal—to support wider application and integration of these technologies; and the application of advanced LC-MS/MS techniques for in-depth characterization of the clinical serum proteome. Collectively, contributions to this Special Issue aim to advance our understanding and utilization of thermal analysis and proteomic approaches to improve cancer diagnostics.

Dr. Nichola C. Garbett
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • thermal analysis
  • proteomics
  • thermal liquid biopsy
  • differential scanning calorimetry
  • mass spectrometry
  • serum proteome
  • clinical diagnostics
  • cancer diagnostics
  • biospecimen

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Published Papers

This special issue is now open for submission.
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