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Biosensors publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Design and Application of Microfluidic Biosensors in Biomedicine

edited by

Hangrui Liu

, Tianlong Zhang and

Yuxin Zhang

submission deadline 15 Oct 2025 | 4 articles | Viewed by 6799 | Submission Open

Keywords: high-throughput technologies; antibody; nucleic acid analysis; single-cell analysis; microfluidic separation; pathogen detection and monitoring; biomarker detection and monitoring; disease diagnostics; point-of-care microdevices; commercialization

(This special issue belongs to the Section Biosensor Materials)

Bioelectronics and Biosensors Using Novel Metal-Oxide and Semiconductor Materials

edited by Ateet Dutt

submission deadline 15 Oct 2025 | 3 articles | Viewed by 6407 | Submission Open

Keywords: biosensors; pathogens; biomarkers; analytes; IoMT; AI; transducer; POC; MIP; wearable sensors; optical; electrochemical

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Functional Materials for Biosensing Applications

edited by

Jin-Ha Choi

submission deadline 20 Oct 2025 | 7 articles | Viewed by 17741 | Submission Open

Keywords: biosensor; early diagnosis; nanoparticle; nanomaterial; functional material; graphene; mxene; organic material; inorganic material

(This special issue belongs to the Section Biosensor Materials)

Latest Wearable Biosensors—2nd Edition

edited by

Donald Y.C. Lie

Tam Q. Nguyen

and Chungchih Hung

submission deadline 25 Oct 2025 | 1 articles | Viewed by 1022 | Submission Open

Keywords: accelerometer activity biosensors; electrocardiogram (ECG); electroencephalography (EEG); mobile phone monitoring; neuroimaging skin conductance; smart phone; smart sensor; vital signs; wearable biosensors; wearable sensors

(This special issue belongs to the Section Wearable Biosensors)

Surface-Enhanced Raman Scattering Biosensors—2nd Edition

edited by

Nicoleta Elena Dina

submission deadline 30 Oct 2025 | 1 articles | Viewed by 2885 | Submission Open

Keywords: SERS; biosensing; miniaturized devices; PoC devices; clinical applications of SERS; SERS-based diagnosis

(This special issue belongs to the Section Optical and Photonic Biosensors)

Advances in Portable and Wearable Sensing Systems for Biochemical Monitoring

edited by

Yanli Lu

and

Zetao Chen

submission deadline 31 Oct 2025 | 11 articles | Viewed by 31495 | Submission Open

Keywords: portable sensing system; wearable system; bioelectronics; biochemical monitoring; self-powered biosensors; in situ biosensing; epidermal patches; implantable sensors; ingestible sensors; biosensors

(This special issue belongs to the Section Wearable Biosensors)

Biosensors Based on Transistors

edited by

Kihyun Kim

and

Meyya Meyyappan

submission deadline 31 Oct 2025 | 7 articles | Viewed by 17812 | Submission Open

Keywords: biosensors; field-effect transistors; BioFETs; electrolyte-gated transistor; flexible biosensor; biomarkers; surface functionalization; diagnostics; point-of-care; clinical applications

(This special issue belongs to the Section Biosensors and Healthcare)

Miniature Sensors Based on Highly Efficient Chemical and Biological Sensing Interfaces

edited by

Ji Qi

and Hongki Kim

submission deadline 31 Oct 2025 | 10 articles | Viewed by 12508 | Submission Open

Keywords: chemical (bio) sensors; paper-based device; portable device; lab on a chip; enzyme-linked immunosorbent assay (ELISA); nanomaterial; molecularly imprinted polymer (MIP); electrochemical analysis; surface-enhanced Raman scattering (SERS); fluorescence; point of care testing (POCT)

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

DNA Molecular Engineering-Based Biosensors

edited by Yifan Lyu

submission deadline 31 Oct 2025 | 4 articles | Viewed by 8820 | Submission Open

Keywords: biosensors; DNA nanotechnology; molecular diagnosis; bioimaging; bioanalysis; functional nucleic acid; aptamers

(This special issue belongs to the Section Biosensors and Healthcare)

Biosensing Applications for Cell Monitoring

edited by Youngdae Yoon

submission deadline 31 Oct 2025 | 5 articles | Viewed by 7887 | Submission Open

Keywords: biosensors; cell monitoring; point-of-care; pathogen; biosensing devices; rapid detection; diagnosis

(This special issue belongs to the Section Biosensors and Healthcare)

Cell-Based Biosensors for Rapid Detection and Monitoring (2nd Edition)

edited by

Georgia Moschopoulou

submission deadline 31 Oct 2025 | 6 articles | Viewed by 7607 | Submission Open

Keywords: analytical devices; bioelectric; cell-based biosensors; enviromental pollutants; food safety; impedimetric biosensors; medical diagnostics; microbial fuel cells; toxicology; synthetic cells

(This special issue belongs to the Section Biosensors and Healthcare)

Advances in Nanozyme-Based Biosensors

edited by

Jiaojiao Zhou

and

Xiangheng Niu

submission deadline 31 Oct 2025 | 3 articles | Viewed by 6125 | Submission Open

Keywords: nanozymes; biosensor; bioimaging; nanozyme-based aptasensor; nanozyme-involved immunoassay; food analysis; environmental detection; nanozyme-based biochemical analysis

(This special issue belongs to the Section Biosensor Materials)

Innovations in Neurochemical and Electrophysiological Sensing: Materials, Devices, and Techniques

edited by

Elisa Castagnola

and

Wen Li

submission deadline 31 Oct 2025 | 1 articles | Viewed by 5614 | Submission Open

Keywords: electrochemical sensors; neural interfaces; fast scan cyclic voltammetry; neurotransmitters

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Application of Nanocomposites for Biosensors

edited by

Paulo A. Raymundo-Pereira

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1832 | Submission Open

Keywords: nanocomposites; biosensors; point-of-care diagnostics; biomolecule detection; biocompatibility; wearables devices; nanomaterials; DNA detection; plant sensors; protein sensors; electrochemical sensors; personalized medicine; therapeutic drug monitoring; diagnosis; biomarkers; biomimetic materials; bioinspired materials; food safety; environmental monitoring; precision agriculture; quality control; security; biomedical; emerging pollutants

(This special issue belongs to the Section Biosensors and Healthcare)

Recent Advances in Biosensor-Integrated Organ-on-a-Chip Technologies for Diagnostics and Therapeutics

edited by

Giuseppe Maruccio

and

Yangzhi Zhu

submission deadline 31 Oct 2025 | Viewed by 282 | Submission Open

Keywords: biosensor; organ-on-a-chip; diagnostics; therapeutics

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Microfluidic Sensors for Biomedical Application

edited by Dan Yuan

submission deadline 31 Oct 2025 | Viewed by 223 | Submission Open

Keywords: microfluidics; lab-on-a-chip; point-of-care diagnostics; organ-on-a-chip; biomedical applications; drug delivery systems; high-throughput screening; biosensors

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Emerging Innovative Approaches in Magnetic Sensor Development for Biosensing Applications

edited by

Antonio Hernando Grande

and

Daniel Matatagui

submission deadline 31 Oct 2025 | Viewed by 158 | Submission Open

Keywords: sensors; biosensors; magnetic; modelling; simulation; synthesis; nanotechnology; bioconjugation; functionalization; magnetostrictive; magnetoresistive; magnetic resonance; wireless sensors

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Sensors for Detection of Bacteria and Their Toxins

edited by Hui Jiang

submission deadline 31 Oct 2025 | Viewed by 147 | Submission Open

Keywords: biosensors; bacteria; bacterial toxins; point of care testing; high-throughput analysis; microfluidic chip; nanomaterials

(This special issue belongs to the Section Biosensors and Healthcare)

The Emerging Techniques in Biosensors and Bioelectronics

edited by

Shunbo Li

submission deadline 1 Nov 2025 | 3 articles | Viewed by 7241 | Submission Open

Keywords: biosensors; nanotechnology; micro/nanofluidics; wearable devices; artificial intelligence

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Wearable Biosensors and Health Monitoring

edited by Xiaoxiang Gao and

Zhengchun Liu

submission deadline 1 Nov 2025 | 4 articles | Viewed by 4563 | Submission Open

Keywords: wearable biosensors; flexible and stretchable bioelectronics; AI in wearable biosensing; multimodal wearable biosensing; multimodal/multifunctional wearable biosensing; biocompatible materials; biosensing textiles; biofunctionalized surfaces; smart materials; graphene-based sensors; sensor integration; human– computer interactions; remote patient monitoring; wearable energy sources; signal processing algorithms; Internet of Diseases (IoD)

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Surface Plasmon Resonance-Based Biosensors and Their Applications

edited by Ya-Hong Xie

submission deadline 1 Nov 2025 | 3 articles | Viewed by 2174 | Submission Open

Keywords: surface plasmon resonance; nano-structures; biosensing; drug discovery; food safety; environmental monitoring; biomarker discovery; diagnostic; proteomics; single-molecule detection; machine learning; protein folding; label-free; plasmonic tweezers; sensitivity; specificity

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Electrochemical Biosensors in Healthcare Services

edited by

Qurat ul ain Zahra

and

Imran Mahmood Khan

submission deadline 1 Nov 2025 | Viewed by 242 | Submission Open

Keywords: electrochemical biosensors; point-of-care diagnostics; wearable and implantable biosensors; nanomaterials in biosensing; lab-on-a-chip technology; chronic disease monitoring; healthcare biosensing; biomarker detection; AI-driven biosensor analytics; personalized medicine

(This special issue belongs to the Section Biosensors and Healthcare)

Aptamer-Based Biosensors for Point-of-Care Diagnostics

edited by

Ana Díaz-Fernández

and

Cecilia Cristea

submission deadline 15 Nov 2025 | 7 articles | Viewed by 9499 | Submission Open

Keywords: aptamer; biosensor; point of care; SELEX; diagnostics; precision medicine

(This special issue belongs to the Section Biosensor Materials)

Advanced Microfluidic Devices and Lab-on-Chip (Bio)sensors

edited by

Pablo Giménez-Gómez

and

Roberto Pilloton

submission deadline 20 Nov 2025 | 7 articles | Viewed by 20684 | Submission Open

Keywords: microfluidics; lab-on-chip; (bio)sensing; integrated systems; point-of-care; point-of-need

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Biosensors Based on Microfluidic Devices—2nd Edition

edited by

Jun Yang

and

Ning Hu

submission deadline 25 Nov 2025 | 11 articles | Viewed by 19018 | Submission Open

Keywords: microfluidics; biosensing; surface plasmon resonance; electrochemical; surfaced-enhanced Raman scattering; portable devices; point-of-care testing; liquid crystal

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Micro/Nanofluidic System-Based Biosensors

edited by

Mengren Wu

Yuan Gao

and

Yang Lin

submission deadline 25 Nov 2025 | 2 articles | Viewed by 5885 | Submission Open

Keywords: microfluidics; nanofluidics; biomarkers; pathogens; pollutants; single cell

(This special issue belongs to the Section Biosensor Materials)

Novel Designs and Applications for Electrochemical Biosensors

edited by Defang Liu and

Kevin C. Honeychurch

submission deadline 25 Nov 2025 | 4 articles | Viewed by 4129 | Submission Open

Keywords: electrochemical; biosensors; electrochemical analysis; nanomaterial; electrochemiluminescence; immunosensor

(This special issue belongs to the Section Biosensor Materials)

Nano/Micro Biosensors for Biomedical Applications (2nd Edition)

edited by

Jin-Ho Lee

and

Ki Su Kim

submission deadline 30 Nov 2025 | 7 articles | Viewed by 14668 | Submission Open

Keywords: biosensors; nano/micromaterials; microsystem; physical; chemical; electrical; electrochemical

(This special issue belongs to the Section Biosensors and Healthcare)

Microfluidics and Organ-on-a-Chip for Disease Modeling and Drug Screening (2nd Edition)

edited by

Rohollah Nasiri

and Mohammadreza Nikmaneshi

submission deadline 30 Nov 2025 | 5 articles | Viewed by 12401 | Submission Open

Keywords: in vitro tissue models; microfluidics; organ on a chip; sensors; microphysiological sensors; lab-on-a-chip; drug screening; disease modeling; 3D bioprinting

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Biosensors for Food Safety

edited by

Ramaraja Ramasamy

, José I. Reyes-De-Corcuera and

Baviththira Suganthan

submission deadline 30 Nov 2025 | 4 articles | Viewed by 9011 | Submission Open

Keywords: bacteria; toxins; pesticidal residue/pesticides; fertilizers; fungus; viruses; food borne pathogens; biosensors; microfluidics

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Nanomaterial-Based Biosensors for Point-of-Care Testing

edited by

Samir Kumar

Satyendra Kumar Mishra

and

Sachin Gupta

submission deadline 30 Nov 2025 | 6 articles | Viewed by 4572 | Submission Open

Keywords: nanomaterials; point-of-care testing (POCT); gold/silver nanoparticles; quantum dots; carbon nanomaterials; optical biosensors; electrochemical biosensors; piezoelectric biosensors; magnetic biosensors; colorimetric biosensors

(This special issue belongs to the Section Biosensor Materials)

Organic Two-Dimensional Material: Synthesis and Biosensing Applications

edited by

Shengbin Lei

submission deadline 30 Nov 2025 | 2 articles | Viewed by 4074 | Submission Open

Keywords: organic two-dimensional materials; biosensor; thin films; field effect transistors; synthesis

(This special issue belongs to the Section Biosensor Materials)

Multidimensional Nanomaterial-Based Biosensors for Environmental and Healthcare Monitoring

edited by

Zhiqiang Su

and

Xiaoyuan Zhang

submission deadline 30 Nov 2025 | 2 articles | Viewed by 3531 | Submission Open

Keywords: multidimensional nanomaterials; biosensors; environmental signals; healthcare sensing; ecological monitoring

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Recent Developments in Micro/Nano Sensors for Biomedical Applications

edited by Federico Mazur and

Elder De la Rosa Cruz

submission deadline 30 Nov 2025 | 3 articles | Viewed by 3463 | Submission Open

Keywords: micro/nanosensors; early diagnostics; lab-on-a-chip systems; microfluidics; real-time therapeutic monitoring; nanomaterials; clinical translation; digital health platforms; biomedical

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Advances in Flexible and Wearable Biosensors

edited by Zhenghan Shi

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2502 | Submission Open

Keywords: flexible biosensors; wearable biosensors; flexible electronics; multimodal biosensing; biofluid analysis; biochemical detection; non-invasive diagnostics; wearable health monitoring; point-of-care testing (POCT); personalized healthcare

(This special issue belongs to the Section Biosensors and Healthcare)

The Application of Biomaterials in Electronics and Biosensors

edited by

Byungil Hwang

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2475 | Submission Open

Keywords: biomaterials; electronics; biosensors; biocompatibility; sustainable technology; wearable technology; health monitoring; environmental sensing; fabrication techniques; interdisciplinary research

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Electrochemical Biosensor Applications in Agriculture, Environment and Health Systems

edited by

Fernando Javier Arévalo

and Adrián Marcelo Granero

submission deadline 30 Nov 2025 | 3 articles | Viewed by 1755 | Submission Open

Keywords: biosensors; biological materials; synthetic materials; agriculture systems; environmental systems; health systems

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Artificial Intelligence (AI) and Machine Learning (ML) in Biosensors: Innovation, Application, and Challenge

edited by

Li Ren

and

Benoît Piro

submission deadline 1 Dec 2025 | 4 articles | Viewed by 4714 | Submission Open

Keywords: biosensors; artificial intelligence; machine learning; precision medicine; biomarkers; point-of-care testing; digital health; smart connected healthcare; quality assessment and monitoring; diagnosis and prognosis

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

New Material-Based Biosensors

edited by

Mingfei Pan

Longhua Xu

and Gaoshuang Hu

submission deadline 1 Dec 2025 | Viewed by 299 | Submission Open

Keywords: matrix effect analysis; food quality and safety; nanomaterials; immunoassay; immunochromatography; molecular imprinting technique; multiple residue detection; multimode detection; visual detection; paper-based sensor

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

The Research and Application of Lateral Flow Biosensors

edited by Guodong Liu

submission deadline 1 Dec 2025 | Viewed by 135 | Submission Open

Keywords: lateral flow biosensors; point-of-care; microfluidics; CRISPR; EXPAR; RPA; LAMP; aptamers; peptides; nucleic acid signal amplification

(This special issue belongs to the Section Biosensors and Healthcare)

Aptamer-Based Sensing: Designs and Applications

edited by

Tao Le

submission deadline 15 Dec 2025 | 4 articles | Viewed by 4220 | Submission Open

Keywords: aptamer; aptasensor; DNA; RNA; screening; point of care; SELEX; diagnostics

(This special issue belongs to the Section Biosensor Materials)

Biosensing and Diagnosis—2nd Edition

edited by

Jiyang Liu

submission deadline 20 Dec 2025 | 8 articles | Viewed by 9987 | Submission Open

Keywords: point-of-care testing; biosensing device; biochemical analysis; diagnostics; biosensor; biosensing; bioimaging

(This special issue belongs to the Section Biosensors and Healthcare)

Sensors for Detection of Virus and Bacteria

edited by

Zhu Chen

submission deadline 20 Dec 2025 | Viewed by 243 | Submission Open

Keywords: bacteria and viruses; nanomaterials; molecular diagnostics; microfluidics and microsystem; artificial intelligence; electrochemical biosensors; optical chemical biosensor

New Progress in Optical Fiber-Based Biosensors—2nd Edition

edited by

Arnaldo Leal-Junior

and

Camilo A.R. Díaz

submission deadline 25 Dec 2025 | 3 articles | Viewed by 3702 | Submission Open

Keywords: optical fiber biosensors; surface plasmon resonance (SPR); localized surface plasmon resonance (LSPR); evanescent field; grating-based sensors; interferometer-based sensors; point-of-care sensors; nanophotonics; surface-enhanced Raman scattering (SERS)

(This special issue belongs to the Section Optical and Photonic Biosensors)

Aptamer-Based Nanosensing Strategy and Applications

edited by

Li Gao

and Jingjie Cui

submission deadline 25 Dec 2025 | 2 articles | Viewed by 3398 | Submission Open

Keywords: aptamers; aptasensor; biosensor; nucleic acid; nucleic acid probe; DNA/RNA; DNA nanostructure

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Molecularly Imprinted Polymers in Biosensors: Assembly, Characterization and Applications

edited by Maria Goreti Ferreira Sales,

Jordi Riu

and

Manuela F. Frasco

submission deadline 25 Dec 2025 | 2 articles | Viewed by 1660 | Submission Open

Keywords: molecularly imprinted polymers; biosensors; electropolymerisation; UV-initiated polymerisation; food analysis; environmental analysis; industrial follow-up; health diagnostics; biomimetic; paper-based analytical devices; lateral flow tests; microfluidics; electrochemical detection; optical detection

(This special issue belongs to the Section Optical and Photonic Biosensors)

Advanced Optical Methods for Biosensing

edited by