Signal Amplification in Biosensing
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 282
Special Issue Editor
Interests: biosensors; redox cycling; immunosensors; DNA sensors; aptasensors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Sensitive and selective detection of chemical and biological targets is of importance in the fields of clinical diagnosis, environmental monitoring, and food quality control. Aiming to achieve excellent performances for the determination of low-abundance analytes, various signal amplification methods have been introduced into optical bioassays to improve the sensitivity, such as enzyme catalysis, nanomaterials, target-recycling, and nucleic acid amplification. In addition, redox cycling is a process that can repeatedly produce or consume signaling species in the presence of reversible redox species or mediators and extra reductants or oxidants. In a typical system, redox cycling can be achieved electrochemically, chemically or enzymatically based on repetitive oxidation–reduction reactions. Redox cycling can be simply coupled with other signal amplification methods, such as enzyme or nanocatalyst-driven chemical reactions and nanomaterial-based containers. Contributions (original articles or comprehensive reviews) to this Special Issue should cover signal amplification to determine various targets, including colorimetry, fluorescence, chemiluminescence, electrochemistry, photoelectrochemistry, electrochemiluminescence, surface-enhanced Raman scattering and so on.
Prof. Dr. Ning Xia
Guest Editor
Manuscript Submission Information
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Keywords
- sensing
- redox cycling
- enzyme catalysis
- immunosensors
- DNA sensors
- aptasensors
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