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Biosensors
Special Issues
Feature Paper in Biosensor and Bioelectronic Devices 2025
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Feature Paper in Biosensor and Bioelectronic Devices 2025

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 435

Special Issue Editors

Prof. Dr. Shunbo Li

E-Mail Website
Guest Editor
College of Optoelectronic Engineering, Chongqing University, Chongqing, China
Interests: microfluidics and nanofluidics; biosensors; SERS
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Benoît Piro

E-Mail Website
Guest Editor
Chemistry Department, University Paris Diderot, Sorbonne Paris Cité, ITODYS, UMR 7086 CNRS 15 rue J-A de Baïf, CEDEX 13, 75205 Paris, France
Interests: bioelectrochemistry; biosensors; bioelectronics; transistor; nanomaterials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue, entitled “Feature Paper in Biosensor and Bioelectronic Devices 2025”, represents an expanding disciplinary field that combines biosensors with various emerging technologies. The field of biosensors and bioelectronic devices has great potential for miniaturization, low-cost, fast, and sensitive analytical detection strategies and devices. This Special Issue’s scope includes, but is not limited to, the design, development, and application of biosensors (enzyme sensors, immunosensors, DNA/RNA sensors, etc.) and bioelectronic devices (electronic nose, electronic tongue, implantable electronics, etc.) in the biological, medical, environmental, and industrial fields, with an emphasis on matters of worldwide interest.

This Special Issue will be composed of original research articles, short communications, as well as review-type articles (e.g., comprehensive and critical literature reviews or review studies based on the author’s recent research experience).

Prof. Dr. Shunbo Li
Prof. Dr. Benoît Piro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sensors
  • biosensors
  • bioelectronic devices
  • micro electro mechanical systems (MEMS)
  • optical biosensors
  • nanotechnology in biosensors
  • flexible and wearable biosensors
  • portable biosensors

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

15 pages, 3390 KiB  
Article
Achievement of 15-Minute Adaptive PCR Benchmark with 1370 nm Laser Heating
by Nicholas Spurlock, Rosana Alfaro, William E. Gabella, Kunal Chugh, Megan E. Pask, Franz Baudenbacher and Frederick R. Haselton
Biosensors 2025, 15(4), 258; https://doi.org/10.3390/bios15040258 - 17 Apr 2025
Viewed by 232
Abstract
In low-resource and point-of-care settings, traditional PCR often faces challenges of poor sample preparation, adverse environmental conditions, and long assay times. We have previously described a laboratory-based instrument to achieve “adaptive” PCR, a PCR thermocycling control system that replaces preset cycling times and [...] Read more.
In low-resource and point-of-care settings, traditional PCR often faces challenges of poor sample preparation, adverse environmental conditions, and long assay times. We have previously described a laboratory-based instrument to achieve “adaptive” PCR, a PCR thermocycling control system that replaces preset cycling times and temperatures with the optical monitoring of added L-DNA stereoisomers matching the sequences of the reaction primers and target. These L-DNA biosensors directly monitor DNA hybridization, compensating for ambient environmental conditions and poor sample preparation. This report describes instrument simplifications and a comparative evaluation of both direct photothermal and plasmonic laser heating to reduce the assay time to 15 min. Instrument performance was assessed using a split sample design to compare reaction performances of 1370 and 808 nm adaptive PCR heating modalities to a standard PCR instrument. Both the novel 1370 nm direct heating and the 808 nm plasmonic method achieved target amplification similar to the traditional PCR system within 15 min. However, a major disadvantage of 808 nm heating was nanorod optical interference that reduced the fluorescence signal from PCR probes and optical cycling components. Further characterization of the 1370 nm direct heating method found comparable limits of detection of 100 copies/µL and reaction efficiencies of approximately 2 for both the 1370 nm system and the traditional PCR instrument. These results suggest that a field-deployable PCR instrument design incorporating both adaptive optical control and 1370 nm laser heating can achieve 15 min sample assay times without sacrificing analytical sensitivity. Full article
(This article belongs to the Special Issue Feature Paper in Biosensor and Bioelectronic Devices 2025)
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