Selected Papers from the 5th International Electronic Conference on Biosensors (IECB 2025)

A special issue of Biosensors (ISSN 2079-6374).

Deadline for manuscript submissions: closed (31 December 2025) | Viewed by 1916

Special Issue Editors


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Guest Editor
Department of Chemistry “Ugo Schiff”, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Italy
Interests: immobilization procedure of biomolecules; protein–DNA complexes; aptamer; enzymatic sensors; thick-film technology; nanodispensing technologies; micro-flow systems; carbon nanotubes; nanoparticles; nanocomposite polymers; molecular imprinted polymers; protein-polymer conjugates
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Special Issue Information

Dear Colleagues,

The 5th International Electronic Conference on Biosensors (IECB 2025) will be held from 26 to 28 May 2025 (https://sciforum.net/event/iecb2025), verifying the great interest of the related community in this Conference Series. The e-conference will be hosted on sciforum.net, an online platform developed by MDPI for scholarly exchange and collaboration.

During the event, a large number of excellent contributions covering key areas of opportunity and challenge will be presented. More specifically, the following areas will be covered:

  • Artificial intelligence in biosensors;
  • Ingestible, implantable, and wearable biosensors;
  • Smartphone-based biosensors;
  • The evolution of biological recognition elements in biosensors;
  • Nanomaterials and smart surfaces in biosensors;
  • Technological advancements in biosensor actuators;
  • Paper-based biosensors;
  • Optical and photonic biosensors.

This Special Issue welcomes selected papers from IECB 2025 that promote and advance this exciting and rapidly changing field.

Submitted contributions will be subjected to peer review and—upon acceptance—will be published with the aim of rapidly and widely disseminating research results, developments, and applications.

It should be noted that submitted manuscripts should have at least 50% additional, new, and unpublished material as compared to the paper presented at IECB 2025.

We look forward to receiving your contributions.

Prof. Dr. Giovanna Marrazza
Dr. Sara Tombelli
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • wearable biosensors
  • implantable biosensors
  • lab-on-a-chip
  • POCT
  • bionanotechnology and nanomaterials
  • microfluidics

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Published Papers (1 paper)

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Research

22 pages, 3050 KB  
Article
A Graphene Field-Effect Transistor-Based Biosensor Platform for the Electrochemical Profiling of Amino Acids
by Roanne Deanne Aves, Janwa El-Maiss, Divya Balakrishnan, Naveen Kumar, Mafalda Abrantes, Jérôme Borme, Vihar Georgiev, Pedro Alpuim and César Pascual García
Biosensors 2026, 16(2), 83; https://doi.org/10.3390/bios16020083 - 29 Jan 2026
Viewed by 1176
Abstract
In this work, we present the introductory methodology for a graphene field-effect transistor (GFET)-based platform for probing the electrochemical fingerprints of amino acids, designed to enable stable and controlled surface chemistry and electrochemical measurements toward peptide and protein sequencing. We begin with a [...] Read more.
In this work, we present the introductory methodology for a graphene field-effect transistor (GFET)-based platform for probing the electrochemical fingerprints of amino acids, designed to enable stable and controlled surface chemistry and electrochemical measurements toward peptide and protein sequencing. We begin with a focused conceptual review that motivates electrochemical fingerprinting as a strategy for amino acid and peptide identification and contextualizes this approach within recent advances in protein manipulation relevant to sequencing. We then describe a graphene functionalization protocol that facilitates the directional attachment of amino acids onto the graphene surface. This surface chemistry is quantitatively characterized through surface plasmon resonance (SPR), yielding surface densities in the order of 1012 molecules/cm2. The same functionalization protocol enables in situ peptide synthesis directly on graphene, as demonstrated by the successful synthesis of a model tripeptide. To support electrochemical interrogation, we developed three complementary platforms for sensor preconditioning, surface functionalization, and titration-based electrochemical measurements, compatible with both aqueous and organic solutions. Preliminary stability measurements indicate a Dirac point drift below 10 mV over 45 min. Altogether, this work establishes the experimental foundations for electrochemical amino acid and peptide fingerprinting using GFET sensors and provides a framework for the future development of electrochemically enabled protein sequencing technologies. Full article
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