Nanomaterial-Assisted CRISPR Biosensing for Health Related Detection

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".

Deadline for manuscript submissions: 1 January 2026 | Viewed by 8

Special Issue Editors

Institute of Medical Research, Northwestern Polytechnical University, Xi'an 710072, China
Interests: luminescence probe; bioimaging; disease diagnosis; CRISPR/Cas-based biosensing; drug screening
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Guest Editor
State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau
Interests: transition metal-based probes; metallodrugs; structure-based drug discovery; luminescent oligonucleotide-based biosensors
Special Issues, Collections and Topics in MDPI journals
Institute of Medical Research, Northwestern Polytechnical University, Xi’an 710072, China
Interests: luminescence probes; CRISPR-based biosensors; luminescence sensing platform
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue focuses on the integration of nanomaterials with CRISPR-based biosensing for health-related detection. It highlights advances in which engineered nanomaterials (e.g., AuNPs, quantum dots) enhance CRISPR-Cas systems to achieve ultrasensitive, rapid, low-cost, and specific detection of health relevant targets—including pathogens, cancer biomarkers, and genetic mutations—in complex environmental, food, and biological samples. Contributions cover novel nanomaterial-CRISPR designs enabling amplified optical, electrochemical, or visual signal readouts for point-of-care use. We seek original research and reviews on fundamental mechanisms, innovative sensor formats, device integration, and clinical applications, driving the development of next-generation, accessible diagnostic tools for early disease detection.

Dr. Wanhe Wang
Prof. Dr. Duncan Chung-Hang Leung
Dr. Jing Wang
Guest Editors

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Keywords

  • CRISPR/Cas
  • biosensing
  • nanomaterial
  • cancer biomarkers
  • biological samples

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Published Papers

This special issue is now open for submission.
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