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Biosensors publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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AI/ML-Enabled Biosensing: Shaping the Future of Disease Detection

edited by

Krishna Kant

submission deadline 15 Jun 2026 | Viewed by 122 | Submission Open

Keywords: microfluidic sensing; electrochemical bio-sensing; point-of-care diagnostics; precision diagnostics; plasmonic sensing; microfluidic devices; lab-on-chip

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Micro and Nano Optic-Based Biosensing Technologies and Strategies—2nd Edition

edited by

Wenchao Zhou

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1442 | Submission Open

Keywords: micro/nano optics biosensors; microfluidics; lab-on-a-chip; Point-of-Care tests; SPR; optical micro/nano fibers; metasurface; nanophotonics

(This special issue belongs to the Section Biosensor Materials)

Surface-Enhanced Raman Scattering in Biosensing Applications

edited by

Hrvoje Gebavi

and

Yuling Hu

submission deadline 30 Jun 2026 | 12 articles | Viewed by 37894 | Submission Open

Keywords: SERS substrate development; SERS for biosensing applications; food contaminant detection; environmental pollution control; machine learning (SERS); SERS sensors; quantitative SERS methods; biohazardous molecules; forensic substances

(This special issue belongs to the Section Optical and Photonic Biosensors)

Feature Papers of Biosensors

edited by

Jun-Jie Zhu

and Tingting Zheng

submission deadline 30 Jun 2026 | 8 articles | Viewed by 22869 | Submission Open

Keywords: biosensor; fluorescence; Raman; mechanical transducers; microfabrication; mass spectral transducers; wearable device

Advanced Lab-on-Chip and Micro-Systems for Manipulation and Bio-Detection

edited by

Kai Zhao

and

Kaihuan Zhang

submission deadline 30 Jun 2026 | 2 articles | Viewed by 13432 | Submission Open

Keywords: microfluidics; LOC devices; dielectrophoretic; microfabrication; target manipulation; signal detection; resolution and throughput

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Biosensors for Environmental Monitoring and Food Safety

edited by

Jing Wei

and Bingxi Feng

submission deadline 30 Jun 2026 | 7 articles | Viewed by 10472 | Submission Open

Keywords: biosensors; nanozyme; nanomaterials; metal oxide; catalysis; environmental monitoring; food safety

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Microfluidics for Sample Pretreatment

edited by

Bing Xu

and

Nan Xiang

submission deadline 30 Jun 2026 | 3 articles | Viewed by 6994 | Submission Open

Keywords: sample pretreatment; plasma separation; blood cell separation; exosome isolation; novel microfluidic separation methods; CTC separation

(This special issue belongs to the Section Biosensors and Healthcare)

Advances in Nanopore Biosensors

edited by Ki-baek Jeong, Sathishkumar Munusamy and Muhammad Asad Ullah Khalid

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3882 | Submission Open

Keywords: nanopore; biosensor; single-molecule detection; biological nanopore; solid-state nanopore; disease diagnosis; DNA detection; protein detection; point-of-care nanopore; nanomaterial; functionalized nanopore; sequencing

(This special issue belongs to the Section Biosensor Materials)

Advances in Biosensors Based on Framework Materials

edited by Peng Ren and Xuemei Yang

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3519 | Submission Open

Keywords: metal organic frameworks; covalent organic frameworks; hydrogen-bonded organic frameworks; hybrid frameworks; biosensing; biosensors

(This special issue belongs to the Section Biosensor Materials)

Mass Sensitive Biosensors for Biomedical Applications

edited by

Tibor Hianik

and

Michael Thompson

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1368 | Submission Open

Keywords: piezoelectric acoustic wave sensors; surface acoustic wave devices; thickness shear mode biosensor

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Fluorescent Probes: Design and Biological Applications

edited by Xiaoyue Han

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1287 | Submission Open

Keywords: fluorescent probe; bioimaging; biosensor

(This special issue belongs to the Section Optical and Photonic Biosensors)

Development and Application of Integrated Optical Devices in Biosensing

edited by Sándor Valkai

submission deadline 30 Jun 2026 | 1 articles | Viewed by 826 | Submission Open

Keywords: integrated optical device; optical biosensor; label-free detection; microfluidics; lab-on-a-chip; interferometer; evanescent wave; whispering gallery mode

(This special issue belongs to the Section Optical and Photonic Biosensors)

Wearable Sensors and Systems for Continuous Health Monitoring

edited by

Shuang Huang

Yeyun Cai

and

Qiangqiang Ouyang

submission deadline 30 Jun 2026 | 2 articles | Viewed by 618 | Submission Open

Keywords: wearable sensors; health monitoring; disease biomarkers; electrophysiological signals; blood pressure and cardiovascular monitoring; motion and activity tracking; personalized healthcare

(This special issue belongs to the Section Wearable Biosensors)

Fluorescent Materials with Excellent Biocompatibility and Their Application in Bio-Sensing, Bio-Imaging (3rd Edition)

edited by

and

submission deadline 30 Jun 2026 | 1 articles | Viewed by 555 | Submission Open

Keywords: fluorescent material; luminescence material; fluorescent probe; fluorescent sensor; biosensor; fluorescent imaging; bioimaging photosensitizer

(This special issue belongs to the Section Biosensor Materials)

Advances in Chemical (Bio)Sensors for the Analysis of Complex Drugs and Hormones

edited by

Iulia Gabriela David

and

Simona Carmen Liţescu

submission deadline 30 Jun 2026 | Viewed by 268 | Submission Open

Keywords: (bio)sensors; biologically active compounds; health; environment; pharmaceuticals; food analysis; hormones; drugs

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Advanced Conductive Hydrogels for Next-Generation Wearable Biosensors

edited by Fei Han

submission deadline 30 Jun 2026 | Viewed by 156 | Submission Open

Keywords: conductive hydrogels; wearables; health monitoring; flexible electronics; multi-functional sensors; biosensing; self-healing; self-adhesion; physiological signal monitoring; polymer composites

(This special issue belongs to the Section Wearable Biosensors)

Application of Biosensors in Tumor Diagnosis, Prognosis, and Dynamic Monitoring

edited by

Longxiang Xie

submission deadline 30 Jun 2026 | Viewed by 148 | Submission Open

Keywords: biosensors; diagnosis; prognosis; cancer; biomarkers

(This special issue belongs to the Section Biosensors and Healthcare)

Innovative Biosensors for Reliable Food Safety and Authentication

edited by

and

submission deadline 30 Jun 2026 | Viewed by 134 | Submission Open

Keywords: biosensors; food safety; food authenticity; food adulteration; food contaminants detection; rapid detection technology; portable biosensing devices; nucleic acid sensors; nanomaterials; molecularly imprinted polymers (MIPs); chemometrics and artificial intelligence (AI); complex food matrices

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Portable, Wearable and Wireless Biosensing Technologies

edited by

Arxel de León Santillán

and

Yuanjing Lin

submission deadline 30 Jun 2026 | Viewed by 113 | Submission Open

Keywords: portable; wearable; wireless; biosensor; pollutant; chronic degenerative disease; agriculture and food biosensors

(This special issue belongs to the Section Wearable Biosensors)

Aptamer-Based Molecular Recognition: State-of-the-Art and Future Perspectives

edited by

Tingjie Song

submission deadline 30 Jun 2026 | Viewed by 99 | Submission Open

Keywords: aptamer; DNA; RNA; SELEX; Biosensing; therapeutics

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Advances in Biomarker-Based Diagnostics: From Discovery to Clinical Application

edited by

Krishna Kant

submission deadline 30 Jun 2026 | Viewed by 88 | Submission Open

Keywords: biomarker; diagnostics; bio-sensing; microfluidic sensing; smart sensor; multiplexed sensor; lab-on-chip

(This special issue belongs to the Section Biosensors and Healthcare)

Novel Implantable and Wearable Biosensors for Healthcare and Personalized Physiological Monitoring

edited by

Lili Xing

submission deadline 30 Jun 2026 | Viewed by 64 | Submission Open

Keywords: implantable biosensors; wearable biosensors; health monitoring; biocompatible materials; biodegradable materials; personalized medicine; flexible electronics; tumor microenvironment; wireless; sensing systems/networks; physiological monitoring

(This special issue belongs to the Section Wearable Biosensors)

Application of Microfluidics in Cell Manipulation and Biosensing—2nd Edition

edited by

Yupan Wu

and

Ye Tian

submission deadline 30 Jun 2026 | Viewed by 58 | Submission Open

Keywords: microfluidic chip; immunoassays; cell manipulation; biosensing; acoustofluidics

(This special issue belongs to the Section Biosensors and Healthcare)

Flexible and Stretchable Biosensors

edited by

Mingcen Weng

and

Peidi Zhou

submission deadline 30 Jun 2026 | Viewed by 55 | Submission Open

Keywords: flexible biosensors; stretchable biosensors; wearable devices; healthcare monitoring; human-machine interaction; biocompatible materials; soft robotics; polymer

(This special issue belongs to the Section Wearable Biosensors)

Functional Nanomaterials for Biosensors

edited by

Dong Liu

and

Wenjia Li

submission deadline 1 Jul 2026 | Viewed by 78 | Submission Open

Keywords: nanomaterials; electrochemical biosensors; optical biosensors; signal amplification; AI-assisted biosensing; wearable sensors; point-of-care diagnostics

(This special issue belongs to the Section Biosensor Materials)

CRISPR/Cas-Based Biosensing Systems: Development and Applications—2nd Edition

edited by

Ki Soo Park

submission deadline 10 Jul 2026 | Viewed by 270 | Submission Open

Keywords: nucleic acid nanotechnology; isothermal amplification; molecular diagnostics; immunological diagnostics; point-of-care testing; biosensors; in vitro diagnostics; clinical applications; CRISPR/Cas protein

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Recent Advances in SERS and SPR Technologies for Biosensors

edited by

Wei Ji

and

Siyu Qian

submission deadline 10 Jul 2026 | Viewed by 119 | Submission Open

Keywords: SERS; fiber-optical SPR; biosensor fabrication; sensing mechanism; sensing principle; food; environment; medicine; bioactive component

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Advances in Flexible Bioelectronics and Intelligent Biosensing Systems—2nd Edition

edited by Shuwen Chen

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1088 | Submission Open

Keywords: bioelectronics; biosensors; flexible sensors; flexible electronics; wearable sensors; healthcare electronics; biomedical electronics; biochemical sensors; bio-interfaced physical sensors; artificial intelligence

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Latest Wearable Biosensors—2nd Edition

edited by

Donald Y.C. Lie

Tam Q. Nguyen

and Chungchih Hung

submission deadline 25 Jul 2026 | 1 articles | Viewed by 1358 | Submission Open

Keywords: accelerometer activity biosensors; electrocardiogram (ECG); electroencephalography (EEG); mobile phone monitoring; neuroimaging skin conductance; smart phone; smart sensor; vital signs; wearable biosensors; wearable sensors

(This special issue belongs to the Section Wearable Biosensors)

Recent Developments in Nanomaterial-Based Electrochemical Biosensors

edited by

Fei Yan

submission deadline 30 Jul 2026 | 4 articles | Viewed by 8088 | Submission Open

Keywords: nanomaterials; electrochemical biosensors; clincial samples anaysis; portable detection; small molecule metabolites; pharmaceutical analysis; pathogen detection; toxin analysis biomarkers detection

(This special issue belongs to the Section Biosensors and Healthcare)

Advanced Luminescent Materials in Biological Detection, Imaging, and Diagnostic Applications

edited by Zhijun Zhang and

Dong Wang

submission deadline 30 Jul 2026 | Viewed by 86 | Submission Open

Keywords: luminescent materials; biosensing; molecular imaging; cellular tracking; in vivo imaging; disease diagnosis

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Biosensor Nanoengineering: Design, Operation and Implementation—2nd Edition

edited by

Dhanjai Dhanjai

and Pramod Kalambate

submission deadline 31 Jul 2026 | 4 articles | Viewed by 6432 | Submission Open

Keywords: nanoengineering; biomaterials; biosensor design and immobilization; biomarkers; smart biosensors; self-powered biosensors; wearable biosensors; plant wearables; AI- and machine learning-enabled biosensors; enzymes; aptamers; and antibodies; stimuli-responsive polymers; three-dimensional-printed sensors

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Functional Nanomaterials for Advanced Biosensing: From Molecular Design to Real-World Applications

edited by

Xiaojun Xian

submission deadline 31 Jul 2026 | 2 articles | Viewed by 3919 | Submission Open

Keywords: functional nanomaterials; biosensors; nanostructured materials; point-of-care diagnostics; biofunctionalization; molecular recognition; smart sensing platforms; biomedical sensing; environmental monitoring; wearable biosensors

(This special issue belongs to the Section Biosensor Materials)

Advanced Nanomaterials for Electrochemical Biosensing Application—2nd Edition

edited by

Sungbo Cho

submission deadline 31 Jul 2026 | 1 articles | Viewed by 742 | Submission Open

Keywords: advanced nanostructured materials; foods; drug delivery; environment; disease; biosensing; DNA nanotechnology; real-time monitoring; smart electrochemical devices; miniaturized devices; paper-based electrochemical sensors

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Recent Progress of In Vitro and In Vivo NanoBiosensors: From Assays, to Diagnostic

edited by

Marita A. Cardoso

Helena M. R. Gonçalves

and

Paula Martins-Lopes

submission deadline 31 Jul 2026 | Viewed by 342 | Submission Open

Keywords: nanotechnology; biotechnology; biosensors; nanomaterials; biomolecules

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Advanced Plasmonics and Surface-Enhanced Technologies in Biosensing Applications

edited by

Ye Ma

Minggang Zhao

and Chenghui Xia

submission deadline 31 Jul 2026 | Viewed by 306 | Submission Open

Keywords: metamaterials; metasurfaces; plasmonics; nanoparticles; quantum dots; SPR; SERS; SEF; biosensing

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Development and Application of Functional Nanomaterial-Based Biosensors

edited by

Nikola Knežević

and

Marija V. Pergal

submission deadline 31 Jul 2026 | Viewed by 194 | Submission Open

Keywords: nanomaterials; nanotechnology; biosensors; lab-on-chip; point-of-need

(This special issue belongs to the Section Biosensor Materials)

Biosensing Technologies in Medical Diagnosis—2nd Edition

edited by Fei Hu and Niancai Peng

submission deadline 31 Jul 2026 | 1 articles | Viewed by 108 | Submission Open

Keywords: diagnostics; biodetection; biosensors; bioseparation; biomaterial; genomics; nucleic acid detection; immunoassay; wearable medical testing; microfluidics and its application to medical testing; cell analysis; point-of-care testing; drug screening; tissue engineering; regenerative medicine; personalized healthcare

(This special issue belongs to the Section Biosensors and Healthcare)

Machine Learning-Assisted Biosensing in Agriculture, Food, and Environmental Applications

edited by Hao Zhang and

Junfeng Wu

submission deadline 31 Jul 2026 | Viewed by 80 | Submission Open

Keywords: machine learning; deep learning; biosensors; nanomaterials; semiconductors; optics; electrochemicals; agriculture; food; environment

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Improving Biosensor Performance Using Surface Chemistry

edited by

Brian De La Franier

submission deadline 31 Jul 2026 | Viewed by 77 | Submission Open

Keywords: surface chemistry; surface functionalization; biointerfaces; anti-fouling strategies; non-specific adsorption; clinical diagnostics; biological monitoring; biosensor performance

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Nanobiosensors for the Rapid Detection of Mosquito-Borne Viruses: Advances, Challenges, and Future Perspectives

edited by

Daniel Sepúlveda-Crespo

submission deadline 31 Jul 2026 | Viewed by 73 | Submission Open

Keywords: artificial intelligence in viral detection; diagnostic performance; microfluidics and lab-on-a-chip; mosquito-borne viruses; nanobiosensors; nanotechnology; point-of-care diagnostics; Chikungunya virus (CHIKV); Dengue virus (DENV); Zika virus (ZIKV)

(This special issue belongs to the Section Biosensors and Healthcare)

Current Trends in Amperometric Biosensors

edited by

Gaia Rocchitta

submission deadline 31 Jul 2026 | Viewed by 49 | Submission Open

Keywords: innovation; wireless data transmission; sensing technologies; amperometric biosensors; biorecognition elements

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Electrochemical Biosensing Platforms for Food, Drug and Health Safety—2nd Edition

edited by

Mihaela Puiu

submission deadline 31 Jul 2026 | Viewed by 41 | Submission Open

Keywords: electrochemical bio(immuno)sensing; organic– inorganic hetero-nano-interfaces; early detection; signal amplification; conductive nanocomposites; magnetic nanoparticles; nanozymes

(This special issue belongs to the Section Biosensors and Healthcare)

Microfabrication of Flexible and Stretchable Bioelectronic Devices: Materials, Structures, and Applications

edited by Su Ding and Ruiliu Wang

submission deadline 31 Jul 2026 | Viewed by 34 | Submission Open

Keywords: microfabrication; bioelectronics; flexible and stretchable devices; biosensor and actuator; personalized healthcare

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Applications of Cutting-Edge Biosensors in Environment, Food and Healthcare Field

edited by

Ying-Chien Chung

submission deadline 1 Aug 2026 | 4 articles | Viewed by 7366 | Submission Open

Keywords: biosensor; food detection; toxicity detection; tumor markers; neuro-biosensors; genetic biosensors; small RNA biosensor

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

AI-Enabled Biosensor Technologies for Boosting Medical Applications

edited by

Carlos G. Juan

and

José María Vicente-Samper

submission deadline 1 Aug 2026 | 3 articles | Viewed by 7218 | Submission Open

Keywords: biosensors; reagents; chemical sensors; electronic sensors; optical sensors; electromagnetic sensors; biomedical applications; artificial intelligence; deep learning; machine learning; medical imaging

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Recent Advances in Photoelectrochemical Biosensors

edited by

Wenbo Lu

submission deadline 25 Aug 2026 | Viewed by 214 | Submission Open

Keywords: photoelectrochemical biosensors; photoactive materials; semiconductor materials; environmental and biomedical applications

(This special issue belongs to the Section Optical and Photonic Biosensors)

Advances in Fluorescent Biosensing

edited by Chen Zhou, Xiao Li and Xiaoli Hu

submission deadline 30 Aug 2026 | Viewed by 77 | Submission Open

Keywords: organic fluorescence sensor; biosensing materials; fluorescent probes; fluorescence bioimaging; sensing mechanism

(This special issue belongs to the Section Optical and Photonic Biosensors)

Artificial Intelligence (AI) and Machine Learning (ML) in Biosensors: Innovation, Application, and Challenge

edited by

Li Ren

and

Benoît Piro

submission deadline 31 Aug 2026 | 6 articles | Viewed by 10015 | Submission Open

Keywords: biosensors; artificial intelligence; machine learning; precision medicine; biomarkers; point-of-care testing; digital health; smart connected healthcare; quality assessment and monitoring; diagnosis and prognosis

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Recent Advances in Microneedle Array Electrodes in Biomedicine

edited by Tianyi Yan and

Bin Wang

submission deadline 31 Aug 2026 | 2 articles | Viewed by 8861 | Submission Open

Keywords: microneedle array; EEG; EMG; ECG; dry electrode; biopotential signal; acquisition; impedance

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

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