Aptamer-Based Molecular Recognition: State-of-the-Art and Future Perspectives
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Nano- and Micro-Technologies in Biosensors".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 9
Special Issue Editor
Special Issue Information
Dear Colleagues,
Aptamers, synthetic single-stranded nucleic acids capable of highly selective molecular recognition, have emerged as versatile tools for probing and controlling biological systems. Their advantages, including predictable synthesis, chemical tunability, structural flexibility, and low immunogenicity, make them attractive alternatives or complements to antibodies and small molecules. As the demand grows for precise recognition elements in diagnostics, therapeutics, and biotechnology, aptamer research continues to expand and evolve.
This Special Issue, “Aptamer-Based Molecular Recognition: State-of-the-Art and Future Perspectives”, is devoted to recent advances and emerging directions in this dynamic field. Areas of interest include new SELEX methodologies, aptamer structural and mechanistic insights, chemical modifications for enhanced affinity and stability, and integration with nanomaterials, biosensing platforms, and imaging technologies. Studies contributing to research on therapeutic aptamers, targeted delivery systems, computational design, and translational challenges are encouraged.
We invite the submission of original research, comprehensive reviews, and short perspectives that reflect the breadth of aptamer science. By uniting interdisciplinary contributions, this collection aims to capture the current state of aptamer-based molecular recognition and outline future perspectives that will guide innovation across chemistry, biology, and medicine.
Dr. Tingjie Song
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- aptamer
- DNA
- RNA
- SELEX
- Biosensing
- therapeutics
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