From Gut to Vascular Health: The Role of Probiiotics, Polyphenols, and Diet in Neuroinflammation and Cardiovascular Dysfunction
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Microbiology in Human Health and Disease".
Deadline for manuscript submissions: 31 October 2026 | Viewed by 57
Special Issue Editors
Interests: nutraceutical supplementation; plant extract; polyphenols; oxidative stress; inflammation; neuroinflammation; microbiota; cardiometabolic dysfunction
Interests: nutraceutical supplementation; plant extract; polyphenols; oxidative stress; inflammation; neuroinflammation; microbiota; cardiometabolic dysfunction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Evidence exists that the gut microbiota contributes to the modulation of oxidative stress and systemic inflammation; its dysfunction is related to brain and cardio metabolic disease onset and development in young patients. In fact, it has been observed that supplementation with probiotics and prebiotics has improved cognitive function, and this is linked to better intestinal and blood–brain barrier integrity and less intestinal inflammation. In humans, oligofructose-enriched inulin changed the gut microbiota in obese patients, reduced body fat and decreased systemic IL-6. The ketogenic diet also helps to prevent neuroinflammation and cardiometabolic dysfunctions by increasing glutathione levels, and has shown a positive influence on the intestinal SCFA profile. Furthermore, new data show that natural polyphenols and fiber help with gut issues and improve dyslipidemia. Indeed, the gut microbiota changes linked to high fat intake are coupled with a changed metabolic profile, weight gain, and altered lipoprotein size. These effects are linked to higher oxidative stress and LPS, thus being key to systemic inflammation. Nutraceutical supplementation may represent a potential strategy to counteract oxidative stress and systemic inflammation, both underlying mechanisms in brain and cardiometabolic dysfunction.
Dr. Maria Serra
Dr. Roberta Macri
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- nutrition supplements
- plant extract
- polyphenols
- oxidative stress
- inflammation
- neuroinflammation
- microbiota
- cardiometabolic dysfunction
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
