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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diagnosis, Pathogenesis, Treatment and Prognosis of Glioblastoma, 2nd Edition

edited by

Paulo Linhares

submission deadline 30 Apr 2026 | Viewed by 46 | Submission Open

Keywords: glioblastoma; immunotherapy; molecular subtype; radiotherapy; molecular therapy; emerging treatment; drug resistance; MRI; immune surveillance

(This special issue belongs to the Section Cancer Biology and Oncology)

Photodynamic Therapy in Cancer—Second Edition

edited by

Shazia Bano

submission deadline 30 Apr 2026 | Viewed by 46 | Submission Open

Keywords: photodynamic therapy; targeted drug delivery and drug release systems; photodiagnosis/tumor imaging; PDT-induced immunogenic cell death; nanomaterials-based combination therapies; theranostics

(This special issue belongs to the Section Cancer Biology and Oncology)

Innovative Therapeutic Strategies and Molecular Mechanisms in Breast Cancer

edited by

Oana Gabriela Trifanescu

and

Laurentia Nicoleta Gales

submission deadline 30 Apr 2026 | Viewed by 45 | Submission Open

Keywords: breast cancer; immunotherapy; medical imaging; biomarkers; translational research

(This special issue belongs to the Section Cancer Biology and Oncology)

New Perspectives on Systemic Amyloidosis: From Pathophysiology to Therapy

edited by Zoltán Pozsonyi and Katalin Révész

submission deadline 30 Apr 2026 | Viewed by 44 | Submission Open

Keywords: systemic amyloidosis; cardiac amyloidosis; light chain amyloidosis; hereditary transthyretin amyloidosis; wild-type transthyretin amyloidosis; amyloidogenesis; disease-modifying treatments; heart failure with preserved ejection fraction

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Genetic Research into Human Reproduction

edited by

Efthalia Moustakli

and Athanasios Zikopoulos

submission deadline 30 Apr 2026 | Viewed by 42 | Submission Open

Keywords: reproductive genomics; assisted reproductive technologies (ARTs); reproductive endocrinology; embryo development; reproductive bioinformatics; precision fertility medicine

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Brain Tumor: From Pathophysiology to Novel Therapies

edited by

Paulo Linhares

submission deadline 30 Apr 2026 | Viewed by 42 | Submission Open

Keywords: glioblastoma; immunotherapy; molecular subtype; radiotherapy; molecular therapy; emerging treatment; drug resistance; MRI; immune surveillance

(This special issue belongs to the Section Cancer Biology and Oncology)

Targeted Biologic Therapies for Allergic Conditions: From Bench to Bedside

edited by

Antonio Francesco Maria Giuliano

and Maria Teresa Ventura

submission deadline 30 Apr 2026 | Viewed by 42 | Submission Open

Keywords: biologics; allergic disease; atopic dermatitis; allergic rhinitis; asthma; precision medicine; biomarkers; immunotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

The Role of Polyamines in Human Health and Disease—Second Edition

edited by

Kuniyasu Soda

submission deadline 30 Apr 2026 | Viewed by 40 | Submission Open

Keywords: polyamine; spermidine; spermine; health; disease; development

(This special issue belongs to the Section Immunology and Immunotherapy)

New Advances in the Treatment of Brain Tumors

edited by

Harim Koo

submission deadline 30 Apr 2026 | Viewed by 38 | Submission Open

Keywords: neuro-oncology; brain tumor; cancer therapy; precision medicine; biomarkers; drug delivery; multi-omics; neurosurgery; clinical trials; bioinformatics

(This special issue belongs to the Section Cancer Biology and Oncology)

Neuropathology: Understanding Local and Systemic Influence of Disease and Vice-Versa

edited by

Kumar Vaibhav

Pankaj Gaur

, Meenakshi Ahluwalia,

Pankaj Ahluwalia

and Shashi Nandar Kumar

submission deadline 30 Apr 2026 | Viewed by 37 | Submission Open

Keywords: brain pathologies; brain injury; Parkinson’ s disease; Alzheimer’ s disease; stroke; neurodegeneration; hemorrhages; hypoxia; neuroinflammation; translational approaches; oxidative stress; COVID-19; gut– brain axis; systemic influence; immune interaction; synaptic plasticity; ageing; senescence; bone marrow and neuropathology; pesticides; preservatives and environmental contamination; lungs and brain; liver and brain; cardiovascular effect of brain pathology and vice-versa; acute and chronic neuro-immune interaction; therapeutic strategies and intervention; alternative medicines in brain pathologies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Isoflavones as Therapeutic Leads: From Natural Sources to Mechanisms and Translational

edited by

Bruno Kaufmann Robbs

and

Lucas Silva Abreu

submission deadline 30 Apr 2026 | Viewed by 32 | Submission Open

Keywords: isoflavones; phytoestrogens; natural bioactive compounds; mechanisms of action; translational medicine; therapeutic development; drug discovery

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

The Brain–Body Interplay in Pain, Anesthesia, and Oncology

edited by

Hui Xu

submission deadline 30 Apr 2026 | Viewed by 30 | Submission Open

Keywords: brain– body axis; neuroimmune communication; microbiome– gut– brain axis; nociception; anesthetic outcomes; cancer biology

(This special issue belongs to the Section Molecular and Translational Medicine)

Selected Papers from the Tanawwo Workshop on Clinical Research in Precision Medicine, Rare Diseases, and Pharmacogenomics (Doha, Qatar, 2025)

edited by

Felipe Fregni

and Radja Messai Badji

submission deadline 30 Apr 2026 | Viewed by 28 | Submission Open

Keywords: precision medicine; rare diseases; pharmacogenomics; adaptive and platform trials; multi-omics integration; artificial intelligence in clinical research; big data and digital health; translational medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Chronic Obstructive Pulmonary Disease (COPD)

edited by Fabio Manzo and

Pasquale Ambrosino

submission deadline 30 Apr 2026 | Viewed by 27 | Submission Open

Keywords: chronic obstructive pulmonary disease; COPD; emphysema; chronic bronchitis; chronic disease; disability; rehabilitation

(This special issue belongs to the Section Cell Biology and Pathology)

New Advances in Cardiovascular Drugs: In Memory of Professor Akira Endo (2nd Edition)

edited by Alfredo Caturano

submission deadline 30 Apr 2026 | Viewed by 20 | Submission Open

Keywords: cardiovascular drugs; statins; metformin; SGLT2i; laboratory; drug targets; translational research; targeted therapy

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Feature Reviews in Gastrointestinal and Liver Diseases

edited by

Agata Michalak

submission deadline 30 May 2026 | Viewed by 234 | Submission Open

Keywords: gastrointestinal diseases; gut– brain interaction; gut microbiota; inflammatory bowel disease; liver disorders; Crohn’ s disease; cancer; fatty liver disease; malnutrition

(This special issue belongs to the Section Molecular and Translational Medicine)

State-of-the-Art Molecular and Translational Medicine in Poland, 3rd Edition

edited by

Małgorzata Wrzosek

and

Arkadiusz Kocur

submission deadline 31 May 2026 | 6 articles | Viewed by 20057 | Submission Open

Keywords: molecular medicine; molecular mechanisms; disease pathogenesis; genetic variants; gene expression; epigenetics; metabolic disorders; cancer

(This special issue belongs to the Section Molecular and Translational Medicine)

Cell Signaling and Molecular Regulation in Neurodegenerative Disease

edited by Shao-Ming Wang

submission deadline 31 May 2026 | 2 articles | Viewed by 10498 | Submission Open

Keywords: neurological diseases; gene regulation; molecular neurobiology; neurodegenerative disease

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Synaptic Function and Modulation in Health and Disease

edited by Jean-Marie C. Bouteiller

submission deadline 31 May 2026 | 4 articles | Viewed by 9807 | Submission Open

Keywords: synaptic function; synaptic plasticity; neurotransmitter release; receptor dynamics

(This special issue belongs to the Section Molecular and Translational Medicine)

Progress in Neonatal Pulmonary Biology

edited by

Fumihiko Namba

submission deadline 31 May 2026 | 3 articles | Viewed by 7993 | Submission Open

Keywords: neonate; preterm infant; bronchopulmonary dysplasia; animal model; in vivo model; in vitro model; basic research; translational research; respiratory outcome; neurodevelopmental outcome

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Cancer Diagnosis and Treatment: Third Edition

edited by

Takaaki Hirotsu

and Hideshi Ishii

submission deadline 31 May 2026 | 4 articles | Viewed by 7001 | Submission Open

Keywords: cancer biology; epigenetics; early detection; diagnosis; biodiagnosis; novel therapeutics; new paradigms

(This special issue belongs to the Section Cancer Biology and Oncology)

Organoid, Organ-on-Chip and Advanced 2D/3D Models for Human Tissue Engineering Applications

edited by

Ahmad Salti

submission deadline 31 May 2026 | 5 articles | Viewed by 6255 | Submission Open

Keywords: organoid; organ-on-chip; 2D/3D model; tissue engineering; induced pluripotent stem cells; in vitro model

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advances in Liver Oncology: Molecular Mechanisms and Therapeutic Innovations

edited by

Rui Caetano Oliveira

, Rui Miguel Martins and

José Guilherme Tralhão

submission deadline 31 May 2026 | 3 articles | Viewed by 5987 | Submission Open

Keywords: liver cancer; hepatocellular carcinoma; cholangiocarcinoma; liver metastases; tumor microenvironment; targeted therapy; immunotherapy; biomarkers; drug resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

Vitamin D: Latest Scientific Discoveries in Health and Disease

edited by

Mohamed Abouzid

submission deadline 31 May 2026 | 3 articles | Viewed by 5815 | Submission Open

Keywords: vitamin D; vitamin D metabolites; metabolic pathways; vitamin D receptor; polymorphisms; pathogenesis; vitamin D deficiency

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advances in Pathogenesis and Therapeutics of Gastrointestinal Diseases

edited by

Jinghua Wang

submission deadline 31 May 2026 | 2 articles | Viewed by 5395 | Submission Open

Keywords: gastrointestinal diseases; IBD; IBS; GERD; functional dyspepsia; gut microbiome

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Regulation of Spermatozoa—Second Edition

edited by

Atefeh Najafi

submission deadline 31 May 2026 | 2 articles | Viewed by 4656 | Submission Open

Keywords: spermatogenesis; spermiogenesis; sperm; capacitation; acrosome reaction; hyperactivation; fertilization; male infertility; antioxidants; redox regulation

(This special issue belongs to the Section Cell Biology and Pathology)

Convergence of Allergology and Immunology: Unveiling Mechanistic Insights

edited by

Kinga Lis

submission deadline 31 May 2026 | 3 articles | Viewed by 3925 | Submission Open

Keywords: allergy; hypersensitivity; allergens; immunological mechanisms; immunological diagnostics; immunotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Advanced Research into Adipose‐Derived Stem Cells

edited by

Anna Barbara Di Stefano

and Mara Franza

submission deadline 31 May 2026 | 1 articles | Viewed by 2814 | Submission Open

Keywords: adipose stem cells; regenerative medicine; stemness; differentiative potential; pre-clinical and clinical applications

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in the Pathogenesis and Treatment of Heart Failure and Cardiomyopathy

edited by

Andrey Jorge Serra

, Ednei Luiz Antonio, Gianna Móes de Albuquerque-Pontes and Luis Felipe Neves dos Santos

submission deadline 31 May 2026 | 3 articles | Viewed by 2793 | Submission Open

Keywords: cardiomyopathy; cardiac remodeling; heart disease; heart failure; mechanisms; new therapies; targeted therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances Research on Nanomedicine

edited by

Rongcheng Han

submission deadline 31 May 2026 | 2 articles | Viewed by 2572 | Submission Open

Keywords: multifunctional nanomaterials; nanomedicine; tumor; theranostics; artificial intelligence (AI); immunotherapy

(This special issue belongs to the Section Biomedical Engineering and Materials)

Osteoarthritis: Molecular Pathways and Novel Therapeutic Strategies—2nd Edition

edited by

Antonia Patruno

Teresa Paolucci

Mirko Pesce

and Andrea Pantalone

submission deadline 31 May 2026 | 2 articles | Viewed by 2508 | Submission Open

Keywords: osteoarthritis; cartilage; pain; orthopedics; rehabilitation

(This special issue belongs to the Section Molecular and Translational Medicine)

The Human Proteinomics in Disease, Diagnostics and Translation into Precision Medicine: Current Status and Future Prospects—2nd Edition

edited by

M. Walid Qoronfleh

submission deadline 31 May 2026 | 3 articles | Viewed by 2270 | Submission Open

Keywords: proteomics; human proteome; systems biology; precision medicine; biomarker(s); disease pathogenesis; diagnostics; mass spectrometry; tandem mass spectrometry; LC-MS/MS; peptides and proteins; multiplex protein analysis; protein network; protein– protein interaction; splice variants; post-translational modifications; omics analysis; data integration; bioinformatics; artificial intelligence; deep learning

(This special issue belongs to the Section Molecular and Translational Medicine)

New Molecular Insights into the Pathogenesis and Drug Development of Neurodegenerative Diseases: 2nd Edition

edited by Aifang Cheng, Beika Zhu and Fulin Ma

submission deadline 31 May 2026 | 1 articles | Viewed by 2267 | Submission Open

Keywords: neurodegenerative diseases; pathogenesis; molecular mechanisms; high-throughput drug screening; drug repurposing; cellular and animal models; brain organoids; mode of action; pharmacological evaluations; preclinical study

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Biomedical Devices—Applications for Disease Treatment and Tissue Regeneration

edited by Eleni Papachristou

submission deadline 31 May 2026 | 1 articles | Viewed by 2265 | Submission Open

Keywords: biomedical devices; mesenchymal stem cell; biomedical applications; Tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advanced Research in Anticancer Inhibitors and Targeted Therapy

edited by

Changmin Peng

and

Hassan Ebrahim

submission deadline 31 May 2026 | 2 articles | Viewed by 2116 | Submission Open

Keywords: histone deacetylases (HDACs); YAP signaling; targeted therapy; oncogenic signaling; biomarker discovery; small-molecule inhibitors; cancer drug resistance; epigenetic therapy

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Biological Role of Oxidative Stress in Inflammatory Processes

edited by

Magdalena Paulina Kasprzak

submission deadline 31 May 2026 | 1 articles | Viewed by 2115 | Submission Open

Keywords: oxidative stress; redox balance; antioxidants; NRF2; microbiota; bilirubin; Tlr4; inflammation

(This special issue belongs to the Section Cell Biology and Pathology)

Rheumatology Diseases: Advances in the Understanding of Pathogenesis, Biomarker Research and Treatment Target

edited by Russka Shumnalieva

submission deadline 31 May 2026 | 2 articles | Viewed by 2082 | Submission Open

Keywords: pathogenesis of rheumatic diseases; epigenetic modifications; biomarkers; new imaging modalities; therapeutic strategies; new treatment targets

(This special issue belongs to the Section Molecular and Translational Medicine)

Gut–Brain Axis and Diabetes

edited by Nikolett Bódi

submission deadline 31 May 2026 | 1 articles | Viewed by 1907 | Submission Open

Keywords: diabetes; gut– brain axis; enteric nervous system; central nervous system; microbiota; enteroendocrine cells; inflammation; immune responses

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Immunotherapy and Targeted Treatment in Solid Tumors: Biomarkers and Novel Therapeutic Strategies

edited by

Dana Lucia Stănculeanu

and

Adelina Silvana Gheorghe

submission deadline 31 May 2026 | 2 articles | Viewed by 1664 | Submission Open

Keywords: immunotherapy; targeted therapy; biomarkers; tumor microenvironment; molecular profiling; precision oncology; treatment resistance; solid tumors; translational oncology

(This special issue belongs to the Section Cancer Biology and Oncology)

Prostate Cancer Pathology: Recent Advances and Future Perspectives

edited by

Kostis Gyftopoulos

submission deadline 31 May 2026 | 1 articles | Viewed by 1647 | Submission Open

Keywords: prostate cancer; pathology; digital pathology; Gleason grading; molecular biomarkers; precision medicine; molecular pathology; molecular profiling; therapy resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

New Trends in Cancer Immunotherapy

edited by Markella Zannikou

submission deadline 31 May 2026 | 1 articles | Viewed by 1543 | Submission Open

Keywords: tumor microenvironment; cancer vaccines; tumor-infiltrating lymphocytes; combination therapy; BITEs; checkpoint inhibitors; CAR T cell therapy; NK cells; antigen presenting cells; tumor associated antigens

(This special issue belongs to the Section Immunology and Immunotherapy)

Advances in Therapeutic Strategies and Precision Medicine in Solid Tumors and Metastasis—2nd Edition

edited by

Silvia Di Agostino

and

Vittoria Rago

submission deadline 31 May 2026 | 1 articles | Viewed by 1432 | Submission Open

Keywords: kinase inhibitor; immunotherapy; chemotherapy; precision molecular therapy; biomarkers; synthetic lethality; theranostics; drug repurposing; radiomics

(This special issue belongs to the Section Cancer Biology and Oncology)

Pathogenesis and Targeted Therapy of Autoimmune Diseases

edited by

Marcella Prete

submission deadline 31 May 2026 | 1 articles | Viewed by 1303 | Submission Open

Keywords: autoimmune diseases; pathogenesis; targeted therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Allergic Rhinitis: From Pathology to Novel Therapeutic Approaches

edited by

Shaoqing Yu

submission deadline 31 May 2026 | 1 articles | Viewed by 1296 | Submission Open

Keywords: allergic rhinitis; immunotherapy; immune mechanisms in allergy; rhinitis biomarkers

(This special issue belongs to the Section Immunology and Immunotherapy)

Unveiling the Genetic Architecture of Complex and Common Diseases

edited by

Mahmut Cerkez Ergoren

submission deadline 31 May 2026 | 2 articles | Viewed by 1203 | Submission Open

Keywords: polygenetic score; cardiovascular disorders; metabolic disorders; neurodegenerative disorders

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advances in Drug Discovery and Development Using Mass Spectrometry

edited by Emily G. Werth,

Amirata Saei Dibavar

and Lin-Zhi Chen

submission deadline 31 May 2026 | 1 articles | Viewed by 1182 | Submission Open

Keywords: LC/MS; proteomics; protein therapeutics; PTMs; immunocapture; CQAs

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Updates on Tissue Repair and Regeneration Pathways

edited by

Cornel Baltă

and

Oana-Maria Boldura

submission deadline 31 May 2026 | 1 articles | Viewed by 1071 | Submission Open

Keywords: tissue repair; tissue regeneration; molecular pathways involved in repair and regeneration; extracellular matrix; drug delivery systems

(This special issue belongs to the Section Biomedical Engineering and Materials)

Past, Present and Further Looking for Therapeutic Management of Pancreatic Ductal Adenocarcinoma (2nd Edition)

edited by

Gennaro Nappo

and

Niccola Funel

submission deadline 31 May 2026 | 1 articles | Viewed by 991 | Submission Open

Keywords: pancreatic cancer; pancreatic ductal adenocarcinoma; treatment pancreatic cancer; chemotherapy pancreatic cancer; radiotherapy pancreatic cancer; pancreatic cancer biology; PDAC preclinical model; biomolecular markers; theragnostic molecules; target therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Drug Discovery and Development: From Rational Design to Experimental Validation

edited by

Vikas Kumar

submission deadline 31 May 2026 | 1 articles | Viewed by 836 | Submission Open

Keywords: drug discovery; drug development; rational drug design; molecular docking; virtual screening; pharmacophore modeling; molecular dynamics simulations; machine learning in drug discovery; deep learning in drug discovery; experimental validation; structure– activity relationship; bioactive compounds

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Neuroscience Through Electrophysiology: Current Trends and Future Directions

edited by

Xiaokuang Ma

submission deadline 31 May 2026 | Viewed by 441 | Submission Open

Keywords: electrophysiology; neural circuit; synaptic plasticity; neuronal membrane; patch-clamp; action potential; ion channels; neurodevelopmental disorders; neurodegenerative disorders

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Displaying special issue 601-650 on page 13 of 15.

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