Gut–Brain Axis and Diabetes
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Endocrinology and Metabolism Research".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 2700
Special Issue Editor
Interests: enteric nervous system; gastroenterology; diabetes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bidirectional communication along the gut–brain axis is fundamental in health and diseases. This close and sensitive relationship between the gastrointestinal system and brain is greatly affected in diabetes. Gastrointestinal symptoms or neuronal-damage-affected central and peripheral nervous systems are common in diabetic patients. Diabetic microbial dysbiosis, chronic low-grade inflammation, and immune responses have critical roles in modulating the gut–brain axis. Gut-derived bacterial metabolites trigger the neuro-inflammatory processes in the enteric nervous system and modulate the brain functions. Gut hormones secreted by enteroendocrine cells are also able to activate the enteric, spinal, or vagal nerve endings, creating critical links among them.
The aim of this Special Issue is to highlight the effects of diabetes on critical elements of the gut–brain axis influencing both gastrointestinal and brain functions. This Special Issue is open for original research articles as well as review articles.
Dr. Nikolett Bódi
Guest Editor
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Keywords
- diabetes
- gut–brain axis
- enteric nervous system
- central nervous system
- microbiota
- enteroendocrine cells
- inflammation
- immune responses
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