Advances in Therapeutic Strategies and Precision Medicine in Solid Tumors and Metastasis—2nd Edition
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 374
Special Issue Editors
Interests: genomic instability; cell cycle checkpoints; dna repair; transcriptional regulation; molecular oncology; head and neck; p53 family; mutant p53; hippo pathway
Special Issues, Collections and Topics in MDPI journals
Interests: male reproduction; testicular cancer; prostate cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue of Biomedicines is dedicated to showcasing the most innovative therapeutic strategies for the treatment of solid tumors.
Understanding molecular cancer pathogenesis has allowed scientists to develop increasingly effective treatment strategies. Over the last decade, whole-genome DNA sequencing technologies such as next-generation sequencing (NGS) have improved our genomic knowledge of several syndromes and diseases, including cancer. Furthermore, a multi-omics approach that also considers the analysis of the transcriptome, proteome, metabolome, and epigenetic DNA modifications could be transformative in better stratifying patients and providing further details on deregulated molecular pathways in tumors. Patients with a poor prognosis due to multiple mechanisms driving therapeutic resistance could also benefit from this multi-omics approach.
In some tumors, the use of personalized medicine throughout treatment, with monoclonal antibodies, immunotherapy, and epigenetic drugs, has already become a reality. In the future, the main objective will be to extend possible molecular targets so that even tumors with a high incidence of metastasis and mortality become more manageable through individualized anticancer therapies.
With this ambitious goal in mind, for this Special Issue, we welcome original research articles and reviews highlighting recent breakthroughs in personalized medicine and novel hypothetical targetable molecular mechanisms in cancer. We welcome contributions that employ robust molecular rationale to address topics in precision molecular therapy, nanodrug and molecule delivery, non-coding RNA-based therapeutics, and novel biomarkers that are useful in early diagnosis and prognosis.
Dr. Silvia Di Agostino
Dr. Vittoria Rago
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- kinase inhibitor
- immunotherapy
- chemotherapy
- precision molecular therapy
- biomarkers
- synthetic lethality
- theranostics
- drug repurposing
- radiomics
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