State-of-the-Art Molecular and Translational Medicine in Poland, 3rd Edition

Dear Colleagues,

New therapeutic approaches require the knowledge and skills of multiple disciplines. The comprehensive exploration of biological mechanisms and the molecular pathogenesis of major human diseases enables personalized treatment. The integration of omics approaches in combination with modeling approaches and systems biology may play a crucial role in establishing novel clinical applications. Furthermore, the sequencing of individual human genomes has provided an opportunity to develop pharmacogenetics in routine medical practice in order to avoid side effects, and choose the most effective drug and dose according to each individual genotype.

For this Special Issue, we seek papers focused on the mechanisms associated with the development of diseases, including cell-to-cell metabolic crosstalk in physiology, pathology and cancer research. New insights into the molecular mechanisms related to therapy effectiveness and changes in gene expression that have important implications for understanding genotype–phenotype maps are also of importance. There is no doubt that further knowledge is required for the future development of clinically relevant guidelines and new methods for the early detection, prevention, treatment and prognosis of diseases.

Dr. Małgorzata Wrzosek
Dr. Arkadiusz Kocur
Guest Editors

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