The Brain–Body Interplay in Pain, Anesthesia, and Oncology
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 2665
Editor
Special Issue Information
Dear Colleagues,
This Special Issue focuses on how signals between the nervous system and peripheral organs shape pain, responses to anesthetic drugs, and cancer biology and outcomes. We welcome studies across basic, translational, and clinical domains that clarify mechanisms and identify measurable targets. Microbiome-related pathways are examples of interest—such as the gut–brain, gut–lung, and gut–liver axes—together with neuroimmune, neuroendocrine, autonomic, and metabolic links that connect the periphery with central circuits. Relevant topics include how microbial metabolites, systemic inflammation, and host metabolism influence nociception and central processing; how anesthetic exposure and depth affect neurocognition and neuroinflammation; and how brain–body communication shapes tumor behavior, immune competence, treatment tolerance, and symptom burden. We encourage work that integrates preclinical and clinical models, employs methods such as multi-omics, imaging, and electrophysiology, and uses sound designs capable of supporting causal interpretation. Submissions may address mechanisms, biomarkers, and interventions (e.g., microbiome-directed, neuromodulatory, or metabolic). The goal is to define concrete pathways and measures that can guide research and practice across pain, anesthesia, and oncology.
Dr. Hui Xu
Guest Editor
Manuscript Submission Information
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Keywords
- brain–body axis
- neuroimmune communication
- microbiome–gut–brain axis
- nociception
- anesthetic outcomes
- cancer biology
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