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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Research in Metabolic Syndrome (2nd Edition)

edited by

Balazs Varga

submission deadline 11 Sep 2026 | 4 articles | Viewed by 7354 | Submission Open

Keywords: obesity; diabetes; dyslipidemia; hypertension; microcirculatory damage; ischemia–reperfusion; necro-apopto-autophagy; laboratory animals; bioactive agents

(This special issue belongs to the Section Cell Biology and Pathology)

Biomarkers and Therapeutic Targets in Gastric Cancer: From Basic Research to Clinical Applications

edited by

Laura Georgiana Necula

submission deadline 11 Sep 2026 | 2 articles | Viewed by 4424 | Submission Open

Keywords: gastric cancer; tumor microenvironment; gastric cancer metastasis; cancer stem cells; diagnosis and treatment; biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

Trends in 3D Printing Processes for Biomedical Field: Opportunities and Challenges (2nd Edition)

edited by

M. R. Mozafari

submission deadline 15 Sep 2026 | 2 articles | Viewed by 9848 | Submission Open

Keywords: 3D/4D bioprinting techniques; 3D bioprinting processes; 3D cellular microenvironment; bio-inks; hydrogels

(This special issue belongs to the Section Biomedical Engineering and Materials)

Prostate Cancer Pathology: Recent Advances and Future Perspectives

edited by

Kostis Gyftopoulos

submission deadline 15 Sep 2026 | 3 articles | Viewed by 5429 | Submission Open

Keywords: prostate cancer; pathology; digital pathology; Gleason grading; molecular biomarkers; precision medicine; molecular pathology; molecular profiling; therapy resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

New Perspectives in the Treatment of Head and Neck Vascular Malformations

edited by Paolo Gennaro

submission deadline 18 Sep 2026 | 1 articles | Viewed by 3476 | Submission Open

Keywords: vascular anomalies; vascular malformations; AVMs; venous malformations; electrosclerotherapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Trends in Cancer: Biomarkers, Therapeutic Strategies and Future Directions

edited by Nedime Serakinci

submission deadline 25 Sep 2026 | 4 articles | Viewed by 2855 | Submission Open

Keywords: cancer biomarkers; stem cells; personalized medicine; emerging cancer therapies; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Obstructive Sleep Apnea: Mechanisms, Comorbidities, and Optimization of Emerging and Established Therapies

edited by

Ivana Pavlinac Dodig

and

Renata Pecotic

submission deadline 29 Sep 2026 | 11 articles | Viewed by 21383 | Submission Open

Keywords: obstructive sleep apnea; sleep-disordered breathing; pathophysiology; cardiometabolic comorbidities; precision medicine; CPAP; sleep diagnostics; biomarkers; neurocognitive impairment; new therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovations in Bone and Craniofacial Tissue Engineering: From Biomaterials and Mechanobiology to Clinical Applications

edited by Zhekai Hu

submission deadline 29 Sep 2026 | 3 articles | Viewed by 3303 | Submission Open

Keywords: bone tissue engineering; craniofacial regeneration; biomaterials and scaffolds; stem cells and exosomes; mechanobiology and orthodontic forces; osteoimmunology; oxidative stress modulation; gene/drug delivery; translational research; periodontal and alveolar bone regeneration

(This special issue belongs to the Section Biomedical Engineering and Materials)

Pathology, Complications and Prognosis of Type 1 Diabetes

edited by Maurizio Delvecchio

submission deadline 29 Sep 2026 | 1 articles | Viewed by 1766 | Submission Open

Keywords: type 1 diabetes mellitus; autoimmune β-cell destruction; diabetic complications; microvascular and macrovascular damage; diabetic ketoacidosis; glycemic control; disease prognosis; immunopathogenesis

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Nervous System Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by Natalia Rozas and Cameron Jeter

submission deadline 30 Sep 2026 | 9 articles | Viewed by 36184 | Submission Open

Keywords: neurodegenerative diseases; neuromuscular diseases; autoimmune diseases of the nervous system; brain diseases; neuroinflammatory diseases; neuromuscular diseases; trauma of the nervous system

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Diabetes: Comorbidities, Therapeutics and Insights (3rd Edition)

edited by

Tomislav Bulum

submission deadline 30 Sep 2026 | 9 articles | Viewed by 22894 | Submission Open

Keywords: diabetes; complications; diabetic retinopathy; diabetic neuropathy; diabetic nephropathy; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Nephrotic Syndrome: Pathomechanism, Diagnostics and Novel Treatment Options—2nd Edition

edited by

Kan Katayama

submission deadline 30 Sep 2026 | 5 articles | Viewed by 19190 | Submission Open

Keywords: focal segmental glomerulosclerosis; genetic kidney disease; minimal change disease; nephrotic syndrome; podocyte

(This special issue belongs to the Section Molecular and Translational Medicine)

Hypertension and Chronic Renal Failure

edited by

Caterina Carollo

submission deadline 30 Sep 2026 | 4 articles | Viewed by 17533 | Submission Open

Keywords: hypertension; chronic renal failure; NephroCardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Parkinson’s Disease: Where Are We and Where Are We Going To

edited by Carmen Borrué

submission deadline 30 Sep 2026 | 1 articles | Viewed by 17405 | Submission Open

Keywords: Parkinson’s disease; gait disorders; biomarkers; neurodegenerative disease; AI

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Gynecological Diseases in Cellular and Molecular Perspectives

edited by

Iwona Wertel

and

Anna Pawłowska-Łachut

submission deadline 30 Sep 2026 | 7 articles | Viewed by 17041 | Submission Open

Keywords: gynaecological diseases; endometriosis; biomarkers; immune checkpoints; immunotherapy; tumor microenvironment; tumor-infiltrating immune cells; cancer immunology; cellular interactions

(This special issue belongs to the Section Molecular and Translational Medicine)

Role of Glycomics in Health and Diseases

edited by

Tijl Vermassen

submission deadline 30 Sep 2026 | 4 articles | Viewed by 16152 | Submission Open

Keywords: glycomics; protein chemistry; immunology; biomarker research

(This special issue belongs to the Section Molecular and Translational Medicine)

Advancements in the Treatment of Colorectal Cancer

edited by

Andee Dzulkarnaen Zakaria

submission deadline 30 Sep 2026 | 8 articles | Viewed by 14896 | Submission Open

Keywords: genomic profiling; advanced nutritional support; AI; MDT; adjuvant therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

New Advances in Chronic Kidney Disease: Biology, Diagnosis and Therapy (3rd Edition)

edited by

Susana Coimbra

and

Alice Santos-Silva

submission deadline 30 Sep 2026 | 11 articles | Viewed by 12820 | Submission Open

Keywords: inflammation; kidney biomarkers; kidney injury; chronic kidney disease; dialysis; cardiorenal syndrome risk; CKD anemia; kidney physiopathology; CKD treatment

(This special issue belongs to the Section Cell Biology and Pathology)

The Molecular Basis of the Immune Response in Pulmonary Fibrosis

edited by

Tamara Cruz

and

Fernanda Hernandez

submission deadline 30 Sep 2026 | 3 articles | Viewed by 11313 | Submission Open

Keywords: immune response; fibrosis; aging; senescence

(This special issue belongs to the Section Immunology and Immunotherapy)

Molecular Research in Ocular Pathology

edited by

Sorin Lucian Bolintineanu

and

Laura Andreea Ghenciu

submission deadline 30 Sep 2026 | 5 articles | Viewed by 11074 | Submission Open

Keywords: molecular pathology; ocular diseases; biomarkers; diabetic retinopathy; glaucoma; age-related macular degeneration; thyroid eye disease; inflammatory pathways; oxidative stress; angiogenesis; neurodegeneration; gene therapy; cell therapy; precision medicine; ocular imaging

(This special issue belongs to the Section Molecular and Translational Medicine)

State-of-the-Art Neonatal Medicine in Japan

edited by

Fumihiko Namba

submission deadline 30 Sep 2026 | 4 articles | Viewed by 10674 | Submission Open

Keywords: mesenchymal stromal cells; artificial placenta; therapeutic gasses; animal models; off-label drug use

(This special issue belongs to the Section Molecular and Translational Medicine)

Skin Diseases and Cell Therapy

edited by Nives Pondeljak, Maryam Heidari Kharaji and Mirna Šitum

submission deadline 30 Sep 2026 | 3 articles | Viewed by 9785 | Submission Open

Keywords: dermatology; psoriasis, atopic dermatitis, vitiligo, alopecia, cutaneous leishmaniasis, and skin fibrosis; skin cancers; innovative therapeutic strategies; molecular mechanisms

(This special issue belongs to the Section Gene and Cell Therapy)

Feature Reviews in Biomaterials for Oral Diseases

edited by

Oliver Schierz

submission deadline 30 Sep 2026 | 3 articles | Viewed by 9482 | Submission Open

Keywords: dental composites; ceramics; zirconia; polymers; polyaryletherketone; polyoxymethylene; titanium; bone graft materials; implants

(This special issue belongs to the Section Biomedical Engineering and Materials)

Next-Generation Nanoparticles: Innovations in Biomedical Applications and Theranostics

edited by

Md Amdadul Huq

submission deadline 30 Sep 2026 | 1 articles | Viewed by 6522 | Submission Open

Keywords: nanoparticles; nanoconjugates; antimicrobial agents; anticancer agents; biomedical applications

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Drug Delivery and Nanocarrier

edited by

Jiawei Huo

submission deadline 30 Sep 2026 | 5 articles | Viewed by 6493 | Submission Open

Keywords: nanocarriers; targeted drug delivery; controlled release; theranostics; biocompatibility; functionalized nanoparticles; nanomedicine; translational nanotechnology

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Cardiomyopathies and Heart Failure: Charting the Future—2nd Edition

edited by Ali Amr

submission deadline 30 Sep 2026 | 3 articles | Viewed by 6405 | Submission Open

Keywords: cardiomyopathies; heart failure; risk stratification; management of cardiomyopathies; cardiac imaging; telemedicine

(This special issue belongs to the Section Cell Biology and Pathology)

Extracellular Vesicles and Exosomes as Therapeutic Agents—2nd Edition

edited by

David J. Rademacher

submission deadline 30 Sep 2026 | 4 articles | Viewed by 6212 | Submission Open

Keywords: extracellular vesicles; exosomes; therapeutics; drug delivery; bioengineering

(This special issue belongs to the Section Cell Biology and Pathology)

New Advances in Insulin—100 Years Since Its Discovery: 2nd Edition

edited by

Tomislav Bulum

submission deadline 30 Sep 2026 | 4 articles | Viewed by 6002 | Submission Open

Keywords: insulin action; insulin analogs; type 1 diabetes; type 2 diabetes; complications; glucose homeostasis

(This special issue belongs to the Section Cell Biology and Pathology)

The Gut Microbiome in Early Life and Beyond: Implications for Health and Disease

edited by

Ye Peng

and

Shilan Wang

submission deadline 30 Sep 2026 | 3 articles | Viewed by 5927 | Submission Open

Keywords: gut microbiome; early-life development; DOHaD; microbial dysbiosis; chronic disease; probiotics; prebiotics; microbiome–host interactions; developmental programming; translational research

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Integrative Roles of Natural Products in Cancer Treatment and Chronic Inflammatory Disease

edited by

Seungho Baek

submission deadline 30 Sep 2026 | 5 articles | Viewed by 5464 | Submission Open

Keywords: natural products; cancer; chronic inflammatory diseases; therapy; oxidative stress

(This special issue belongs to the Section Molecular and Translational Medicine)

Neural Nexus: Interdisciplinary Perspectives on Neurological Disorders

edited by Gianandrea Traversi,

Marianna Mazza

and Giuseppe Marano

submission deadline 30 Sep 2026 | 1 articles | Viewed by 4265 | Submission Open

Keywords: neurological disorders; mental health; artificial intelligence; machine learning; biomarkers; drug discovery; therapeutic targets; neuroscience research

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Urothelial Carcinoma: Role of Biomarkers in Diagnosis, Prognosis and Treatment (2nd Edition)

edited by Ioannis Zachos and

Panagiotis Vlachostergios

submission deadline 30 Sep 2026 | 2 articles | Viewed by 4207 | Submission Open

Keywords: urothelial carcinoma; biomarker; diagnosis; treatment; prognosis

(This special issue belongs to the Section Molecular and Translational Medicine)

New Insights into Breast Cancer Management: From Tumorigenesis to Personalized Treatments—2nd Edition

edited by

Rita De Sanctis

and

Paola Tiberio

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4139 | Submission Open

Keywords: breast cancer; diagnosis; prognosis; treatment response prediction; biomarkers; risk factors; new therapies

(This special issue belongs to the Section Cancer Biology and Oncology)

New Insights in Respiratory Diseases (2nd Edition)

edited by

Diego Bagnasco

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4002 | Submission Open

Keywords: asthma; COPD; bronchiectasis; genetic; therapeutics

(This special issue belongs to the Section Molecular and Translational Medicine)

Obesity and Obesity-Related Pathology

edited by

Adriana Grigoraș

submission deadline 30 Sep 2026 | 4 articles | Viewed by 3902 | Submission Open

Keywords: obesity; obesity-related cardiovascular diseases; obesity-related chronic kidney diseases; diabetes mellitus; depression; obesity-related cancer; adipose tissue; adipocytes; cancer-associated adipocytes; obesity therapies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Next-Generation Approaches to Hepatobiliary Disorders

edited by

Lorenzo Petagna

submission deadline 30 Sep 2026 | 2 articles | Viewed by 3572 | Submission Open

Keywords: hepatobiliary disorders; interventional radiology; interventional endoscopy; advances in HPB surgery; advances in liver transplantation; liver transplant viability biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms, Implications and Therapeutic Targets in Infectious Diseases—2nd Edition

edited by

Mihai Lazăr

and

Oana Săndulescu

submission deadline 30 Sep 2026 | 3 articles | Viewed by 3302 | Submission Open

Keywords: infectious diseases; virus; antibiotics; pathophysiology; molecular mechanism; therapeutic management

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research in Liver Diseases

edited by

Marta Melis

submission deadline 30 Sep 2026 | 3 articles | Viewed by 3163 | Submission Open

Keywords: liver; obesity; alcohol; oxidative stress; nutrients; vitamins; metabolism; homeostasis

(This special issue belongs to the Section Cell Biology and Pathology)

The Tumor Microenvironment and Heterogeneity: Challenges and Opportunities in Multiple Myeloma Immunotherapy

edited by

Enze Liu

submission deadline 30 Sep 2026 | 2 articles | Viewed by 3160 | Submission Open

Keywords: multiple myeloma; immunotherapies; tumor microenvironment; novel targets; surfaceome; expression heterogeneity

(This special issue belongs to the Section Cancer Biology and Oncology)

Recent Advances in Chronic Rhinosinusitis and Asthma: 2nd Edition

edited by

Giuseppe Guida

and Cristiano Caruso

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2956 | Submission Open

Keywords: asthma; chronic rhinosinusitis; nasal polyps; severe asthma; type-2 inflammation; phenotypes; endotypes; biologics; epithelial disfunction; remodeling

(This special issue belongs to the Section Molecular and Translational Medicine)

Sepsis and Systemic Inflammation: Mechanisms and Therapeutic Innovations

edited by

Christian Lehmann

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2874 | Submission Open

Keywords: sepsis; systemic inflammation; microcirculation; intravital imaging; immune dysregulation; septic shock; therapeutic innovations

(This special issue belongs to the Section Immunology and Immunotherapy)

The Pivotal Role of Mucosal Immunity in Health and Disease

edited by Eunsoo Kim

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2562 | Submission Open

Keywords: mucosal immunity; gut–organ axis; immune homeostasis; environmental pollutants; vaccine adjuvants and delivery; immunomodulation

(This special issue belongs to the Section Immunology and Immunotherapy)

Supraventricular and Ventricular Cardiac Arrhythmias Systemic Implications: From Mechanisms to Clinical Treatment

edited by

Alina Negru

and

Gabriel Cismaru

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2452 | Submission Open

Keywords: cardiac arrhythmias; atrial fibrillation; ventricular tachycardia; AVNRT; PVC; supraventricular tachycardia; catheter ablation; electrophysiological study; heart failure; arrhythmias diagnostic; antiarrhythmic treatment; biomarkers; ion channels; cardiac resynchronization therapy; ICD

(This special issue belongs to the Section Molecular and Translational Medicine)

Applications of Mass Spectrometry in Biomedical Research

edited by Robin Joshi

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2215 | Submission Open

Keywords: metabolomics; multiomics; method development; mass spectrometry; proteomics and post-translational modifications in disease; translational medicines

(This special issue belongs to the Section Molecular and Translational Medicine)

Natural Product for the Interventions of Chronic Diseases: From Source to Therapy—2nd Edition

edited by

Qilei Chen

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2074 | Submission Open

Keywords: natural products; chronic diseases; drug discovery; pharmacodynamics; pharmacokinetics; nanotechnology

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advances in Neurological Diseases: Pathogenesis, Diagnosis and Therapeutic Strategies (2nd Edition)

edited by

Foteini Christidi

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2029 | Submission Open

Keywords: neurological diseases; neurodegenerative diseases; stroke; multiple sclerosis; epilepsy; neuromuscular disorders; demyelinating diseases; traumatic brain injury; clinical neurophysiology; neuroimaging; genetics; neuropsychological tests; molecular and cellular mechanisms; biomarkers; diagnosis and therapeutics; prognosis; neurorehabilitation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Biomarker Discovery for Cardiovascular Disease—2nd Edition

edited by

Qin Fu

and

Haijun Liu

submission deadline 30 Sep 2026 | 3 articles | Viewed by 1814 | Submission Open

Keywords: cardiovascular disease; genomics; transcriptomics; proteomics; metabolomics; multiomics; gene sequencing; liquid chromatography/gas chromatography tandem mass spectrometry; diagnostic biomarkers; biomedicine; insulin resistance; hyperinsulinemia

(This special issue belongs to the Section Molecular and Translational Medicine)

Signaling of Protein Kinases in Development and Disease (2nd Edition)

edited by

John Zheng Fu

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1781 | Submission Open

Keywords: kinase; phosphorylation; signaling; mutation; mechanism; development; inhibitor; disease

(This special issue belongs to the Section Cell Biology and Pathology)

Genetic Insights and Pharmacogenomic Approaches in Cancer Treatment

edited by

Ana Fernández-Santander

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1621 | Submission Open

Keywords: pharmacogenetics; genetic basis; cancer treatments

(This special issue belongs to the Section Cancer Biology and Oncology)

Precision Approaches in the Diagnosis and Management of Inflammatory Bowel Disease

edited by

Jiayu Ye

and Andrea Verdugo-Meza

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1586 | Submission Open

Keywords: inflammatory bowel disease; ulcerative colitis; Crohn’s disease; precision medicine; microbiome-based therapy; noninvasive diagnostics; stratified therapeutic response; immunometabolism; system immunology; therapeutic repurposing

(This special issue belongs to the Section Cell Biology and Pathology)

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