Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancing Translational Science Using Bioinformatics and Big Data-Driven Approaches
edited by
submission deadline 30 Apr 2026 | 3 articles | Viewed by 2727 | Submission Open
Keywords: bioinformatics; big data analytics; artificial intelligence (AI); machine learning; deep learning; translational science; computational biology; drug repositioning; biomarker discovery; genomics; medical imaging; digital pathology; integrative analysis; disease mechanisms; functional genomics analysis; computational tool application; ethical and safety considerations; data-driven approaches
(This special issue belongs to the Section Bioinformatics)
Molecular Basis of Seed Germination and Dormancy
edited by , , and Yu Cheng
submission deadline 30 Apr 2026 | 2 articles | Viewed by 2455 | Submission Open
Keywords: molecular mechanism; genetic basis; seed germination; dormancy; genetic improvement
(This special issue belongs to the Section Plant Science)
Recent Advances in Animal Anatomy submission deadline 30 Apr 2026 | 1 articles | Viewed by 2238 | Submission Open
Keywords: animal anatomy; comparative morphology; imaging anatomy; molecular anatomy; veterinary anatomy; functional morphology; evolutionary biology; wildlife conservation; developmental anatomy; anatomical adaptations
(This special issue belongs to the Section Zoology)
Epigenetic and Genetic Control of Sperm Development and Function: From Fertility to Inheritance submission deadline 30 Apr 2026 | 1 articles | Viewed by 1815 | Submission Open
Keywords: spermatogenesis; epigenetics; sperm; male fertility; DNA methylation; histone modifications; small RNAs; epigenetic inheritance
(This special issue belongs to the Section Genetics and Genomics)
Natural Compounds Targeting 12 Hallmarks of Aging: A Path to Longevity Intervention submission deadline 30 Apr 2026 | Viewed by 851 | Submission Open
Keywords: natural compounds; antiaging interventions; hallmarks of aging; telomere; epigenetics; autophagy; cellular senescence; pharmaceuticals
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Advances in Cell and Experimental Biology: Cellular Organelle Stress and Homeostasis in Physiology and Diseases
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 587 | Submission Open
Keywords: autophagy; integrated stress response; proteotoxic stress response; organelle homeostasis; ubiquitination
(This special issue belongs to the Section Cell Biology)
Machine Learning in Pathogen Discovery
edited by
submission deadline 30 Apr 2026 | Viewed by 346 | Submission Open
Keywords: pathogen; machine learning; disease; antibiotic; virulence
(This special issue belongs to the Section Bioinformatics)
Effects of Aquatic Sediments on Marine Ecosystems
edited by Ehui Tan and Sibo Zhang
submission deadline 30 Apr 2026 | Viewed by 330 | Submission Open
Keywords: biogeochemical cycling processes; microbial activity; sediment– water interface; benthic organisms; pollutants; global change; nutrients; environmental issues
(This special issue belongs to the Section Ecology)
The Molecular Mechanisms of Chronic Inflammation Occurrence and Development
edited by Meixiu Jiang
submission deadline 30 Apr 2026 | Viewed by 320 | Submission Open
Keywords: atherosclerosis; vascular calcification; neointima; macrophage; inflammation; phenotypic transformation of smooth muscle cell; endothelial dysfunction
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Germplasm Resources and Molecular Breeding for Sustainable Aquatic Species Improvement
edited by Falin Zhou
submission deadline 30 Apr 2026 | Viewed by 156 | Submission Open
Keywords: germplasm resource evaluation; molecular marker; genomics; gene editing; selective breeding; environment adaptation
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Animal Models for Disease Mechanisms (2nd Edition)
edited by
submission deadline 30 Apr 2026 | Viewed by 140 | Submission Open
Keywords: animal models; spontaneous models; induced models; disease mechanisms; pathogenesis research
(This special issue belongs to the Section Zoology)
Research Progress in Microbial Genetics and Genomics
edited by and Udomluk Leungtongkam
submission deadline 30 Apr 2026 | Viewed by 139 | Submission Open
Keywords: antimicrobial resistance (AMR); microbial genetics and genomics; high-throughput DNA sequencing; comparative genomics and pan-genome; metagenomics and microbiome; mobilome; resistome and virulome; medical microbiology; environmental and food microbiology; probiotic genomics; bacteriology; mycology and virology
(This special issue belongs to the Section Microbiology)
Natural Compound–Drug Interactions Related to Metabolizing Enzymes and Transporters
edited by
submission deadline 30 Apr 2026 | Viewed by 124 | Submission Open
Keywords: drug transporters; drug-metabolizing enzymes; natural products; herb– drug interactions; food– drug interactions; nuclear receptors; kinases; expression regulation; protein targeting; functional regulation
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Cutting-Edge Biomechanics: Unlocking the Future of Biomedical Engineering
edited by
submission deadline 30 Apr 2026 | Viewed by 110 | Submission Open
Keywords: computational biomechanics; experimental biomechanics; cellular and molecular biomechanics; tissue biomechanics and regenerative engineering; cardiovascular biomechanics; musculoskeletal biomechanics; sports and injury biomechanics; biomaterials and medical device innovation; medical robotics and haptics; AI and machine learning in biomechanics
(This special issue belongs to the Section Biophysics)
Advances in Cell Division and Chromosome Segregation Mechanisms
edited by
submission deadline 30 Apr 2026 | Viewed by 76 | Submission Open
Keywords: cell division; chromosome segregation; bacterial cell biology; mammalian cell cycle; genome stability; cytoskeletal dynamics; structural biology; advanced imaging
(This special issue belongs to the Section Cell Biology)
Population Genomics in Biodiversity Conservation in the Neotropics
edited by Rubens Pasa, Caroline Garcia and Karine Frehner Kavalco
submission deadline 30 Apr 2026 | Viewed by 9 | Submission Open
Keywords: biodiversity; genomics; conservation; bioinformatics; population genomics
(This special issue belongs to the Section Conservation Biology and Biodiversity)
The Impact of Climate Change on Quality, Yield, and Nutritional Properties of Cereals, Legumes, and Oilseeds
edited by
submission deadline 1 May 2026 | 1 articles | Viewed by 2154 | Submission Open
Keywords: climate change; cereals; legumes; oilseeds; grain quality; seed nutrition; yield; elevated temperatures; drought; salinity; atmospheric CO2; multi-omics; field trials; crop modelling; data integration; climate resilience; breed-ing strategies; agronomic practices; beneficial microorganisms; underutilised crops; orphan crops
(This special issue belongs to the Section Plant Science)
Microbial Contamination and Food Safety (Volume II)
edited by
submission deadline 15 May 2026 | 5 articles | Viewed by 16597 | Submission Open
Keywords: food contamination; food safety practices; microbial inactivation; microbial safety; microbiological hazards
(This special issue belongs to the Section Microbiology)
Internal Defense System and Evolution of Aquatic Animals
edited by
submission deadline 15 May 2026 | 8 articles | Viewed by 14540 | Submission Open
Keywords: internal defense system; evolution; aquatic animals; immunology; aquatic environment; biodiversity; pollution; ecosystems
(This special issue belongs to the Section Evolutionary Biology)
Genetic and Genomic Insights into Cardiovascular Disease
edited by Silvio Zaina and
submission deadline 15 May 2026 | Viewed by 120 | Submission Open
Keywords: coronary and carotid atheroma; lipids; thrombosis; inflammation; vascular calcification; vascular smooth muscle cells; foam cells; endothelium; immune cells; epigenetics; genetic variation; gene expression and proteomics; cell and disease models
(This special issue belongs to the Section Genetics and Genomics)
The Biology of Animal Reproduction
edited by
submission deadline 30 May 2026 | 9 articles | Viewed by 13223 | Submission Open
Keywords: the regulation of animal reproduction; follicular development and atresia; gamete and embryo development; hormonal control of reproductive processes; epigenetic regulation in reproductive biology
(This special issue belongs to the Section Developmental and Reproductive Biology)
Genetic Variability within and between Populations
edited by
submission deadline 31 May 2026 | 18 articles | Viewed by 15383 | Submission Open
Keywords: genetic structure; population differentiation; FST or fixation index; migration; gene flow; admixture; heterozygosity; inbreeding; coalescence time; allele frequency; random mating
(This special issue belongs to the Section Evolutionary Biology)
Aquatic Animal Nutrition and Feed
edited by
submission deadline 31 May 2026 | 8 articles | Viewed by 10670 | Submission Open
Keywords: aquaculture; aquatic animals; nutrition; aquatic feed; immunity; metabolism
Application of Bioinformatics to Unravel the Molecular Mechanisms of Cancer Biology
edited by
submission deadline 31 May 2026 | 6 articles | Viewed by 10280 | Submission Open
Keywords: cancer biology; bioinformatics; genetics; epigenetics; transcriptomics
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Artificial Intelligence Research for Complex Biological Systems submission deadline 31 May 2026 | 7 articles | Viewed by 9114 | Submission Open
Keywords: deep learning; generative artificial intelligence; bioinformatics; complex biological systems; cancer; neuroscience; next-generation sequencing; single-cell and bulk omics; genomics
(This special issue belongs to the Section Bioinformatics)
Stem Cells in Experimental Medicine
edited by Xinhua Liao and
submission deadline 31 May 2026 | 1 articles | Viewed by 8830 | Submission Open
Keywords: adult stem cells; induced pluripotent stem cells (iPSs); embryonic stem cells; progenitor cells; stem-cell-derived organoids; stem-cell-derived exosomes; stem-cell-based therapy; stem-cell-based disease modeling; stem-cell-based tissue engineering
(This special issue belongs to the Section Cell Biology)
Young Researchers in Conservation Biology and Biodiversity
edited by
submission deadline 31 May 2026 | 4 articles | Viewed by 5188 | Submission Open
Keywords: population genomics and diversity; heterozygosity; inbreeding; hybridization; adaptive introgression; natural selection; speciation; bottleneck and population fragmentation; genetic drift; gene flow; extinction risk; evolvability; paleogenomics; phylogeography; conservation units; ecotypes; phylogenetics and systematics; eDNA; non-invasive genetic sampling; environmental monitoring
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Mechanisms Underlying Neuronal Network Activity
edited by Jorge Flores-Hernandez
submission deadline 31 May 2026 | 2 articles | Viewed by 4621 | Submission Open
Keywords: neurons; brain circuits; NMDA receptors; acetylcholine; excitability; Parkinson’ s; schizophrenia; learning; attention
(This special issue belongs to the Section Neuroscience)
Research Progress on Salt Stress in Plants
edited by
submission deadline 31 May 2026 | 3 articles | Viewed by 2666 | Submission Open
Keywords: salt stress; plants; crops; soil salinization; salt tolerance; abiotic stress; plant protection; plant breeding
(This special issue belongs to the Section Plant Science)
New Insights in Cancer Genetics—2nd Edition
edited by , Isabel Marques Carreira and
submission deadline 31 May 2026 | 1 articles | Viewed by 2593 | Submission Open
Keywords: genomic and epigenetic characterization; diagnosis and prognosis biomarkers; omics profiles; genetic and genomic signature; molecular heterogeneity; molecular targeted therapy; oncogenic signaling pathways; copy number alterations and mutational landscape; chromosome abnormalities
(This special issue belongs to the Section Cancer Biology)
The Biology and Behavior of Bees
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 2259 | Submission Open
Keywords: pollinators; bee anatomy; bee foraging behavior; bee communication; bee social structure; environmental stressors of bees; effect of pesticide on bees’ behavior; bees’ habitat loss; natural enemies of bees; bees’ disease management
(This special issue belongs to the Section Zoology)
Impact of Climate Change on Structural and Functional Characteristics of Freshwater Ecosystems and Its Implications for Their Resources’ Management submission deadline 31 May 2026 | 1 articles | Viewed by 2258 | Submission Open
Keywords: AI applications; biodiversity; biological assemblages; climate change; ecological resilience; ecosystem ser-vices; freshwater ecosystems; nutrient cycling; temperature
(This special issue belongs to the Section Ecology)
Recent Advances in Metabolic Disorders
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 1762 | Submission Open
Keywords: iron; mitochondria; oxidative stress; inflammation; metabolism; free radicals; alcohol; treatment   TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Physiology)
The Role of Lipids in Cardiovascular and Neurodegenerative Diseases
edited by , and Yaxin Li
submission deadline 31 May 2026 | 1 articles | Viewed by 1572 | Submission Open
Keywords: lipid biology; lipid peroxidation; lipidomics; lipid foods or nutrients; cardiovascular disease; neurodegenerative diseases
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Recent Advances in Biological Research on Prostate Cancer
edited by Samson Mashele and Pakiso Makhoahle
submission deadline 31 May 2026 | 1 articles | Viewed by 1428 | Submission Open
Keywords: prostate cancer; biological research; molecular mechanisms; biomarkers; precision medicine; therapeutic targets; tumor microenvironment; therapeutic resistance; genomics; quality of life
(This special issue belongs to the Section Cancer Biology)
Head and Neck Cancer: Current Advances and Future Perspectives
edited by Ana Jotic
submission deadline 31 May 2026 | 1 articles | Viewed by 1004 | Submission Open
Keywords: head and neck cancer; tumor microenvironment; genetic and epigenetic alterations; oncogenes and tumor suppressor genes; signal transduction pathways; immune evasion; metastasis; drug resistance mechanisms; molecular etiology; cancer biology
(This special issue belongs to the Section Cancer Biology)
Coping with Temperature Increase Induced by Climate Warming: Trends in Ectothermic Species—2nd Edition
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 802 | Submission Open
Keywords: biodiversity; climate warming; ectothermic species; geographic ranges; heat waves; evolutionary adaptations; phenotypic plasticity; species interactions; thermal acclimation
Understanding and Targeting Biological Mechanisms of Heart Failure (2nd Edition)
edited by and
submission deadline 31 May 2026 | Viewed by 698 | Submission Open
Keywords: developmental biology; genetics; stem cells; heart failure; cell therapy
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Molecular and Neurological Aspects of Sensory Processing Disorders submission deadline 31 May 2026 | Viewed by 556 | Submission Open
Keywords: sensory processing; sensory processing disorders; SPDs; sensory stimuli; brain activity; genetic; functional neuroimaging studies
(This special issue belongs to the Section Neuroscience)
Studies on Antioxidant Activity of Natural Products from Plants submission deadline 31 May 2026 | Viewed by 393 | Submission Open
Keywords: plant natural products; phytochemicals; antioxidant activity; free radical scavenging; functional foods; oxidative stress-accelerated diseases
(This special issue belongs to the Section Plant Science)
Understanding Syncope: Multidisciplinary Approaches to Diagnosis and Management
edited by and Sérgio Laranjo
submission deadline 31 May 2026 | Viewed by 342 | Submission Open
Keywords: syncope; diagnostic strategies; prognostication; treatment options; quality of life; wearable devices; artificial intelligence; autonomic dysfunction; orthostatic hypotension; POTS (postural orthostatic tachycardia syndrome)
(This special issue belongs to the Section Neuroscience)
Machine Learning Advanced Research on Ecosystem Carbon and Nitrogen Cycles
edited by Fenghui Yuan and
submission deadline 31 May 2026 | Viewed by 167 | Submission Open
Keywords: machine learning; biogeochemical cycles; ecosystem modeling; carbon cycling; nitrogen cycling; greenhouse gas; climate change; land-use change; data assimilation
(This special issue belongs to the Section Ecology)
Pluripotent Stem Cells in Development and Disease
edited by
submission deadline 31 May 2026 | Viewed by 151 | Submission Open
Keywords: pluripotent stem cells (PSCs); early development; regenerative medicine; genetic/epigenetic factors; differentiation; cell fate determination; disease modelling; organoids; genomic editing; single-cell omics
(This special issue belongs to the Section Developmental and Reproductive Biology)
Animal Models for Immune and Infectious Diseases
edited by Shijun Zheng
submission deadline 31 May 2026 | Viewed by 145 | Submission Open
Keywords: animal models; immune responses; autoimmunity; infectious diseases; host– pathogen interaction; immunotherapies
Studies on Insect Genetics and Genomics
edited by Ying Lin
submission deadline 31 May 2026 | Viewed by 129 | Submission Open
Keywords: novel sequencing technologies; genome-editing methods; sex chromosome origins; horizontal gene transfer; resource insects; eco-friendly insect control technologies; genomics; ecology; molecular biology; insect
(This special issue belongs to the Section Genetics and Genomics)
Wetland Ecosystems (2nd Edition)
edited by , Chenglang Pan and Qiang Wang
submission deadline 1 Jun 2026 | 17 articles | Viewed by 37600 | Submission Open
Keywords: biological invasion; pollution; carbon sink function; the biogeochemical cycle of biogenic elements; population and community ecology; global climate change; coastal zone management; the structure and function of the microbiome; environmental adaptation mechanisms of wetland organisms; wetland landscape; wetland degradation
(This special issue belongs to the Section Ecology)
Animal Models of Neurodegenerative Diseases
edited by Xiangyu Guo
submission deadline 1 Jun 2026 | 6 articles | Viewed by 17544 | Submission Open
Keywords: neurodegenerative diseases; Alzheimer's disease; amyotrophic lateral sclerosis; Parkinson's disease; Huntington's disease; neuroscience; animal models; pathogenesis
(This special issue belongs to the Section Neuroscience)
Biomarkers in Stress Biology and Ecology submission deadline 1 Jun 2026 | 4 articles | Viewed by 9781 | Submission Open
Keywords: biomarkers; ecotoxicology; environmental contamination; stress ecology; neurotoxicity; oxidative stress; pollution
Interactions and Cross-Kingdom Regulation of Hosts and Pathogens/Parasites
edited by and Jianfeng Qiu
submission deadline 1 Jun 2026 | Viewed by 159 | Submission Open
Keywords: host; pathogen; parasite; interaction; cross-kingdom regulation; immune response; infection
(This special issue belongs to the Section Microbiology)
Sustainable Waste Management: Application of Biotechnology to Reduce Waste
edited by and Hande Ermis
submission deadline 1 Jun 2026 | Viewed by 100 | Submission Open
Keywords: sustainable waste management; environmental biotechnology; microbial waste treatment; bioresource valorization; circular economy; waste-to-energy; bioreactors and bioprocesses; enzymatic degradation; industrial and municipal waste treatment
(This special issue belongs to the Section Biotechnology)
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