Lysosomes and Diseases Associated with Its Dysfunction
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cell Biology".
Deadline for manuscript submissions: 15 November 2025 | Viewed by 15453
Special Issue Editor
2. Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), 28049 Madrid, Spain
Interests: autophagy; Parkinson disease; acetylation; myotonic dystrophy
Special Issue Information
Dear Colleagues,
Lysosomes are metabolic sensors and play a key role in the regulation of metabolism. As degradative organelles, the catabolic function of lysosomes is accomplished by hydrolases, lipases, nucleases and proteases. Metabolites (nucleotides, amino acids sugars, lipids) generated by lysosomal degradation are exported to the cytoplasm to be reused. Moreover, lysosomes have the ability to tether with other membrane organelles, including endoplasmic reticulum and mitochondria, to coordinate the cellular metabolic response. Abnormalities in endosomes and lysosomes or dysregulation in their trafficking could be associated with various disorders. This Special Issue welcomes original research relating to this theme in the field of biology and biomedicine. Reviews describing signalling pathways and methodology articles highlighting recommendations and cautions for the study and characterization of these organelles are also welcome.
Dr. Sokhna M.S. Yakhine-Diop
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- activities
- mutations
- endocytosis
- autophagy
- metabolism
- proteins
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.