Animal Models in Toxicology

Dear Colleagues,

For an animal model of toxicology to be relevant to human health, the route of administration/exposure, the exposure dose(s) and the pattern/frequency of doses should all be justified and defined in terms of overall applicability to human physiology and potential physiological disruption and then ideally similar across studies to allow for comparisons between and among studies. This set of statements should be arguably true independent of chemical, drug, etc. being scientifically assessed/studied. However, complexities will, of course, exist and include questions surrounding route of exposure, e.g., dermal, ingestion or inhalation. In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: studies aimed at the development and/or use of (novel) animal models to address human health concerns related to chemically defined substances, such as drugs, with regard to well-perceived or as of yet not perceived toxicological effects; using animal models to study or derive new biomarkers of harm; or studies aimed at exploring or defining the numerous routes of exposure of a single chemical. Appropriate and thorough reviews of existing animal models of toxicology would also be especially welcomed.

Dr. Rob U. Onyenwoke
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• animal model
• biomarker of harm
• pharmacokinetics
• route of exposure
• toxicology
• toxin