Mitochondrial Dysfunction and Aging
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Medical Biology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 1084
Special Issue Editor
Special Issue Information
Dear Colleagues,
Biology is calling for submissions to our Special Issue on “Mitochondrial Dysfunction and Aging”. The mitochondria not only work in energy production but also play important roles in reactive oxygen species (ROS and RNS) production, calcium handling, metabolism, cell signaling, etc. Mitochondria have been increasingly recognized as important players in the aging process. Mitochondrial dysfunction is one of the hallmarks of aging and aging-related diseases, including cardiovascular dysfunction, neurodegenerative diseases, skeletal muscle decline, kidney dysfunction, skin aging, immune dysfunction, and stem cell dysfunction. As individuals age, they become increasingly susceptible to various clinical complications. There is an urgent need to elucidate the mechanisms of mitochondrial dysfunction and seek mitochondrial-targeted treatments in aging. In this Special Issue, we welcome submissions of original research, reviews, and mini-reviews. Subtopics of interests include, but are not limited to, the following:
1) Mitochondrial DNA damage, reactive species (ROS and RNS) production, dynamics, and metabolism disorders in aging;
2) Mitochondrial dysfunction in various diseases in aging, including cardiovascular diseases, neurodegenerative diseases, Alzheimer’s diseases and related dementia, etc.;
3) Mitochondria and immune dysfunction in aging;
4) Mitochondrial dysfunction in stem cell aging;
5) Mitochondria and skeletal muscle cell dysfunction in aging;
6) Epigenetic regulation and potential targets in mitochondria in aging;
7) Other mitochondrial dysfunction in aging research.
Dr. Huiliang Zhang
Guest Editor
Manuscript Submission Information
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Keywords
- mitochondrial dysfunction
- aging
- cardiovascular diseases
- Alzheimer’s disease and related dementia
- stem cell
- skeletal muscle
- kidney
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