Exploring the Molecular Basis of Cancer: Perspectives from Genetics and Epigenetics
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Genetics and Genomics".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 1746
Special Issue Editor
Interests: cancer genetics; epigenetics; tumor heterogeneity; histone modification; next-generation sequencing (NGS); cancer transcriptomics; gene regulation; mouse model; chromatin remodeling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer remains a significant global health challenge, prompting extensive research into its molecular foundations to discover new therapeutic strategies. Advances in genetic and epigenetic analyses, along with integrated "omics" techniques—such as genomics, transcriptomics, proteomics, and epigenomics—are reshaping our understanding of cancer biology. The molecular basis of cancer involves complex genetic and epigenetic changes that drive tumor initiation, progression, and therapeutic resistance.
This Special Issue aims to enhance our understanding of these molecular mechanisms through innovative research in genetics, epigenetics, and integrated "omics" approaches, offering new insights into the diverse and dynamic biology of cancer. We invite submissions of original research, reviews, short communications, perspectives, and commentaries that explore the role of bioinformatics and machine learning in cancer biology. Relevant topics include, but are not limited to, tumor subtype classification, immunotherapy, T cell exhaustion, gene regulation, cancer prognosis, cancer transcriptomics, epigenomics, and predictive models for drug response.
The goal of this Special Issue is to highlight innovations that will improve precision medicine and deepen our understanding of cancer mechanisms. By showcasing recent discoveries in genetic and epigenetic mechanisms, we aim to foster insights that will lead to innovative therapies and personalized treatment approaches for cancer.
Dr. Shilpa Dhar
Guest Editor
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Keywords
- cancer genetics
- epigenetics
- tumor heterogeneity
- histone modification
- next-generation sequencing (NGS)
- cancer transcriptomics
- gene regulation
- mouse model
- chromatin remodeling
- CHIP-Seq
- ATAC-seq
- mutation
- amplification
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