Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Young Investigators in Biochemistry and Molecular Biology
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 1651 | Submission Open
Keywords: protein structure and function; DNA Methylation; apoptosis; computational biology; molecular development biology; molecular enzymology; molecular evolution; molecular immunology; molecular virology; systems biology; proteins and nucleic acids; protein trafficking; proteomics; structural and functional genomics; transcriptomics; signaling
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Feeding Biology and Nutrition in Insects
edited by and Christopher W. Weldon
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1275 | Submission Open
Keywords: diet; digestion; ecology; evolution; feeding; insects; mass-rearing; microbiome; nutrients; taste
(This special issue belongs to the Section Ecology)
Young Researchers in Plant Sciences
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1010 | Submission Open
Keywords: biodiversity; biogeography; biotic and abiotic stress responses; carbon sequestration; ecosystem functions; gene– function relationships; photosynthesis; phytohormones; phytoremediation; plant interactions with viruses; bacteria; fungi; plants; and animals; primary and secondary metabolism; seed development; signalling pathways; structure– function simulation modelling
(This special issue belongs to the Section Plant Science)
RNA Biology and mRNA in Diseases
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 896 | Submission Open
Keywords: stress granule; cRISPR/Cas13; vaccine; mRNA drug; antisense oligonucleotides; RNA methylation; microRNA; long non-coding RNA; RNA binding; RNA activation; circular RNA; fluorescent RNA; cell surface RNA; cancer; neurodegenerative disease
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Responses and Resistance Mechanisms of Plants Under Environmental Stress
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 825 | Submission Open
Keywords: disease resistance; cold tolerance; defense priming; pathogen perception
(This special issue belongs to the Section Plant Science)
Sustainable Management of Aquatic Animal Health: Advances in Immunology, Pathogenesis, and Innovative Disease Control Strategies
edited by and
submission deadline 31 Dec 2025 | 2 articles | Viewed by 802 | Submission Open
Keywords: aquatic animal health; immunology; pathogenesis; CRISPR-based innovations; sustainable aquaculture
(This special issue belongs to the Section Immunology)
Large Animal Experimental and Epidemiological Models for Diseases submission deadline 31 Dec 2025 | 1 articles | Viewed by 741 | Submission Open
Keywords: large animal model; dog; pig; ruminants; experimental study; epidemiological study; infectious diseases; non-infectious diseases; treatment; disease control; disease prediction
(This special issue belongs to the Section Medical Biology)
The Potential of Genetics and Plant Breeding in Crop Improvement
edited by Jianyan Zeng, and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 651 | Submission Open
Keywords: plants; plant signaling pathways; growth and development; genomics; transcriptomics; proteomics; metabolomics; gene transformation; molecular biology; biochemistry; molecular breeding; genome editing; CRISPR/Cas9; marker-assisted selection; genome-wide selection; crop improvement; genetic diversity; quality traits; yield; disease resistance; environmental stress; plant-microbe interactions; drought tolerance; salinity resistance; oxidative stress; phytohormone
(This special issue belongs to the Section Plant Science)
Unveiling Novel Gene Functions: Mechanisms, Evolution and Applications
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 640 | Submission Open
Keywords: Novel Gene Mechanisms; Molecular Pathways; Systems Biology; Moonlighting Genes; Adaptive Evolution; Synthetic Biology Applications
(This special issue belongs to the Section Genetics and Genomics)
Advances in Aquatic Ecological Disasters and Toxicology
edited by and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 579 | Submission Open
Keywords: aquatic ecological disasters; aquatic toxicology; aquatic ecosystem; algal blooms; pollutants
(This special issue belongs to the Section Ecology)
The Application of Microorganisms and Plants in Soil Improvement submission deadline 31 Dec 2025 | 2 articles | Viewed by 424 | Submission Open
Keywords: environmental microbiology; microbial diversity; microbial metabolism; nutrient transformation; plant growth promotion; rhizosphere effect; soil improvement
(This special issue belongs to the Section Microbiology)
Radiation and Biology: Investigating Cellular, Organismal, and Environmental Responses submission deadline 31 Dec 2025 | 1 articles | Viewed by 422 | Submission Open
Keywords: radiation-induced DNA damage and repair pathways; oxidative stress and redox signaling in radiation response; radiation-induced epigenetic modifications; radiation-induced immunomodulation and inflammation; radiation-induced carcinogenesis and disease susceptibility; ecological consequences of ionizing radiation
(This special issue belongs to the Section Medical Biology)
Young Researchers in Immunology
edited by and Moses New-Aaron
submission deadline 31 Dec 2025 | Viewed by 420 | Submission Open
(This special issue belongs to the Section Immunology)
Adaptation and Protection Mechanisms in Marine Ecosystem Under Climate Change
edited by and Ya-Fan Chan
submission deadline 31 Dec 2025 | Viewed by 284 | Submission Open
Keywords: global climate change; seawater acidification; marine ecosystem; marine biology; marine biogeochemistry TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in Zulu   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate Zulu to Simplified Chinese Never translate Zulu Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
State of the Art in Fish Nutrition: Antimicrobials, Immunostimulants, Synbiotics and Alternative Protein Sources
edited by Jiun-Yan Loh
submission deadline 31 Dec 2025 | Viewed by 225 | Submission Open
Keywords: probiotics; prebiotics; synbiotics; immunostimulants; antimicrobial peptides; alternative protein/single-cell protein sources; insect meals; aquatic species; metabolisms; disease resistances
(This special issue belongs to the Section Zoology)
Human Papillomavirus (HPV) and Carcinogenesis: Recent Advances
edited by
submission deadline 31 Dec 2025 | Viewed by 215 | Submission Open
Keywords: mucosal and cutaneous HPVs; squamous cell carcinoma; tumorigenesis; therapy; prognostic and diagnostic markers
(This special issue belongs to the Section Medical Biology)
Experimental Biology, Life Science and One Health: From Basic to Translational Research
edited by
submission deadline 31 Dec 2025 | Viewed by 207 | Submission Open
Keywords: anatomy; histology; embryology; aquatic environment and ecosystem; biotechnology and bioengineering; cell stress; environment and health; extracellular vesicles; fight against cancer; movement and nutrition science; neuroscience; plant ecology and ecosystem; regenerative biomedicine
Protein Kinases: Key Players in Carcinogenesis
edited by Yingyu Cui
submission deadline 31 Dec 2025 | Viewed by 143 | Submission Open
Keywords: protein kinases; carcinogenesis; molecular mechanisms; kinase inhibitors; cancer stem cells
(This special issue belongs to the Section Cancer Biology)
Organ-on-a-Chip: Biology Meets Technology
edited by Julia Mantaj
submission deadline 31 Dec 2025 | Viewed by 143 | Submission Open
Keywords: human biology; disease modelling; drug development; novel therapies; personalized medicine; organ-on-a-chip technology; novel technology
(This special issue belongs to the Section Biotechnology)
Improving Knowledge of Pharmacotoxicology and Biomedical Analysis of Drugs of Abuse and New Psychoactive Substances
edited by Nunzia La Maida and
submission deadline 31 Dec 2025 | Viewed by 136 | Submission Open
Keywords: new psychoactive substances (NPSs); drug toxicity; LC-HRMS/MS; GC-MS/MS; bioassay
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Mode of Action of Allelopathic Compounds
edited by and Paweł Staszek
submission deadline 31 Dec 2025 | Viewed by 120 | Submission Open
Keywords: metabolomics; phytotoxic potential; mode of action; sustainable bioherbicides; root exudates; plant– plant interaction; plant– microbe interaction; metabolic malformations; biosynthesis of allelochemicals
(This special issue belongs to the Section Plant Science)
Mechanisms of Genetic and Epigenetic Regulation Underlying Plant Resistance to Biotic Stresses
edited by Feng Zhang, and
submission deadline 31 Dec 2025 | Viewed by 108 | Submission Open
Keywords: plant biotic stresses; multi-omics; genetic engineering; genome editing; epigenetic regulation
(This special issue belongs to the Section Plant Science)
Plant Developmental Transition Under Changing Climate
edited by Zeeshan Nasim
submission deadline 31 Dec 2025 | Viewed by 97 | Submission Open
Keywords: plant development; reproductive transition; flowering; climate change; global warming TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
Pathobiology of Cardiac Arrhythmias and Heart Failure Issues
edited by Mohit Hulsurkar
submission deadline 31 Dec 2025 | Viewed by 93 | Submission Open
Keywords: cardiac arrhythmias; atrial fibrillation; heart failure; ion channelopathy; cardiac fibrosis; cardiomyopathy
(This special issue belongs to the Section Physiology)
Research on Morphology and Sensorimotor Systems of Insect Antennae
edited by Lifeng Meng
submission deadline 31 Dec 2025 | Viewed by 83 | Submission Open
Keywords: antennae structure; sensilla; olfaction; olfactory receptors; sensory integration; antenna lobe; pheromones; predator avoidance; foraging behavior
(This special issue belongs to the Section Zoology)
Insecticide Resistance: Molecular Mechanisms and Ecological Implications
edited by Kaikai Mao
submission deadline 31 Dec 2025 | Viewed by 77 | Submission Open
Keywords: insecticide resistance; molecular mechanism; regulatory network; ecological impact; non-target impact; resistance genes; pest resistance management
(This special issue belongs to the Section Ecology)
Mammalian Oocyte Biology
edited by Jingcai Liu
submission deadline 31 Dec 2025 | Viewed by 74 | Submission Open
Keywords: oocyte; oogenesis; meiosis; oocyte maturation; oocyte quality; activation; oocyte metabolism; aneuploidy
(This special issue belongs to the Section Developmental and Reproductive Biology)
Sickle Cell Disease: Molecular Mechanisms, Pathogenesis and Therapies
edited by Chithra Palani
submission deadline 31 Dec 2025 | Viewed by 51 | Submission Open
Keywords: SCD; anemia; erythrocyte development; erythroid progenitors; CD34 cells; vaso-occlusion; pain crisis; hemolysis; oxidative stress; sickling; inflammation; ER stress; fetal hemoglobin; hematopoiesis; ischemia and tissue damage; organ damage; drug development; SCD diagnosis; gene therapy; cell therapy
(This special issue belongs to the Section Medical Biology)
Living Resources of the Deep Sea: Biological Profiles and Environmental Linkages
edited by and
submission deadline 31 Dec 2025 | Viewed by 39 | Submission Open
Keywords: deep-sea fisheries; spawning-ground shifts; habitat– environment coupling; rare deep-sea biodiversity; molecular adaptation; environmental DNA (eDNA); acoustic monitoring; fishery remote-sensing
(This special issue belongs to the Section Marine Biology)
Molecular Mechanisms of Bone Metastasis in Cancer
edited by Ana Carolina Dos Santos Monteiro
submission deadline 15 Jan 2026 | Viewed by 18 | Submission Open
Keywords: bone metastasis; osteoimmunology; tumor– immunity interactions; myeloid-derived suppressor cells; RANKL/OPG signaling; TGF-β ; Wnt; immune evasion; extracellular vesicles; metastatic niche; cancer cell dormancy; preclinical models
(This special issue belongs to the Section Cancer Biology)
Genetic and Epigenetic Regulation of Gene Expression
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 585 | Submission Open
Keywords: allele-specific expression; cis-regulatory elements; RNA maturation and stability; DNA methylation; histone modifications; chromatin remodeling; transcription factors; non-coding RNA; small RNA
(This special issue belongs to the Section Genetics and Genomics)
Fungal Biodiversity and Ecology: Unraveling Ecological Roles, Interactions, and Environmental Adaptations
edited by Xin Qian, Junzhi Qiu and Yonglong Wang
submission deadline 31 Jan 2026 | Viewed by 89 | Submission Open
Keywords: fungal biodiversity; fungal ecology; ecosystem functioning; community assembly; fungal interactions; taxonomy and systematics; extreme environments; biogeography; fungal conservation; biotechnology applications
(This special issue belongs to the Section Ecology)
Tumor Biomechanics and Mechanobiology
edited by Xinbin Zhao
submission deadline 31 Jan 2026 | Viewed by 71 | Submission Open
Keywords: tumor migration; cancer cell invasion; cancer metastasis; biomechanics; tumor microenvironment; extracellular matrix; matrix degradation
(This special issue belongs to the Section Cancer Biology)
Sexual Determination and Reproductive Regulation in Aquatic Organisms
edited by Liang Guo
submission deadline 31 Jan 2026 | Viewed by 67 | Submission Open
Keywords: sex-determining gene; sex chromosome; sex control breeding; sex-determining pathway
(This special issue belongs to the Section Developmental and Reproductive Biology)
Molecular Interactions and Biological Functions of Bioactive Compounds in Food and Health submission deadline 31 Jan 2026 | Viewed by 60 | Submission Open
Keywords: bioactive compounds; nutraceuticals; food function; healthy effects; antidiabetic action; anti-inflammatory properties; antioxidants
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Advances in Animal Functional Genomics
edited by Chugang Mei
submission deadline 31 Jan 2026 | Viewed by 21 | Submission Open
Keywords: functional genomics; gene editing; phenomics; epigenetics; livestock; conservation; CRISPR; host– microbiome interactions
(This special issue belongs to the Section Zoology)
Synaptic Function and Energy Use
edited by
submission deadline 15 Feb 2026 | Viewed by 694 | Submission Open
Keywords: presynapse; postsynapse; ATP; mitochondria; glia; pericyte; vasculature; fatty acids; ketone bodies; leptin; insulin; glucose; lactate
(This special issue belongs to the Section Neuroscience)
Cell Self-Destruction (Programmed Cell Death), Immunonutrition and Metabolism (2nd Edition) submission deadline 15 Feb 2026 | 1 articles | Viewed by 662 | Submission Open
Keywords: autoimmunity; cell self-destruction; infection; inflammation; immunonutrition; lipotoxicity; metabolism; programmed cell death
(This special issue belongs to the Section Immunology)
Gut Microbiota in Aquatic Animals Nutrition, Immunity, and Host–Microbe Interactions
edited by Qunlan Zhou
submission deadline 15 Feb 2026 | Viewed by 20 | Submission Open
Keywords: gut microbiota; aquatic animal health; host– microbe interactions; functional probiotics; immunomodulation; nutrient metabolism; multi-omics integration; microbial ecology; environmental adaptation
(This special issue belongs to the Section Microbiology)
Plant Nutrition—Molecular Biology and Genetics
edited by Guohua Mi and
submission deadline 24 Feb 2026 | 1 articles | Viewed by 303 | Submission Open
Keywords: plant nutrition physiology; root development and regulation; plant genetics; high-efficiency crop agronomy technologies
(This special issue belongs to the Section Plant Science)
Roles and Functions of Neurotrophins and Their Receptors in the Brain (2nd Edition) submission deadline 24 Feb 2026 | Viewed by 68 | Submission Open
Keywords: aging; behavior; learning; memory; mental disorders; neuroanatomy; neurobiology; neuronal plasticity; neurophysiology; synaptic plasticity
(This special issue belongs to the Section Neuroscience)
Physiology and Pathophysiology of Skin
edited by Seon-Pil Jin
submission deadline 28 Feb 2026 | 6 articles | Viewed by 10684 | Submission Open
Keywords: epidermal barrier; melanogenesis; wound healing; skin immunity; sensory perception; dermatitis; psoriasis; atopic dermatitis; autoimmune skin disorders; therapeutic approaches
(This special issue belongs to the Section Physiology)
Bioavailability, Metabolism, and Health Effects of Phenolic Compounds
edited by and Alice Cattivelli
submission deadline 28 Feb 2026 | 3 articles | Viewed by 4669 | Submission Open
Keywords: phenolic compounds; gut microbiota; metabolism; cardiovascular diseases; cancer; anti-proliferative activity; bioavailability; bioaccessibility
(This special issue belongs to the Section Biochemistry and Molecular Biology)
RNA Biology and Roles in Diseases
edited by Nan Wu and
submission deadline 28 Feb 2026 | 2 articles | Viewed by 2597 | Submission Open
Keywords: RNA biology; diseases; circRNA; mRNA; non-coding RNA
(This special issue belongs to the Section Biochemistry and Molecular Biology)
AI Deep Learning Approach to Study Biological Questions (2nd Edition) submission deadline 28 Feb 2026 | 1 articles | Viewed by 2490 | Submission Open
Keywords: OpenCV; Mask RCNN; YOLO; U-Net; StarDist; ImageJ; MATLAB; image segmentation; image classification; locomotion trajectory analysis; volumetric prediction; plants; animals; protozoa; invertebrates; animal behavior; developmental biology; toxicology; zebrafish; medaka; daphnia
(This special issue belongs to the Section Bioinformatics)
Nutraceutical and Bioactive Compounds in Foods
edited by and
submission deadline 28 Feb 2026 | 2 articles | Viewed by 2157 | Submission Open
Keywords: bioactive compounds; functional food ingredients; nutraceuticals; antioxidant and anti-inflammatory agents; metabolic regulation; biotechnology in food science; gut microbiota interactions   This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Biotechnology)
Animal Models of Autoimmune Diseases
edited by Feng Zhu and Keqiang Chen
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1704 | Submission Open
Keywords: autoimmune disease; infection; innate immunity; inflammation; cancer risk; therapeutic target; adaptive immunity
(This special issue belongs to the Section Physiology)
Advancements in Mesenchymal Stem Cell-Derived Secretome
edited by Chiara Giannasi
submission deadline 28 Feb 2026 | Viewed by 188 | Submission Open
Keywords: mesenchymal stem cells; secretome; extracellular vesicles; conditioned medium; cell-free therapeutics; regeneration; immunomodulation; inflammation
(This special issue belongs to the Section Cell Biology)
Uncovering the Intricate Relationship Between the Human Microbiome and Chronic Diseases
edited by
submission deadline 28 Feb 2026 | Viewed by 88 | Submission Open
Keywords: gut microbiome; oral microbiome; metabolomics; proteomics; inflammation; multi-omics; diet; cardiovascular diseases; type 2 diabetes mellitus
(This special issue belongs to the Section Medical Biology)
Photomorphogenesis and Stress Response Mechanisms Involving Light in Plants
edited by Ilektra Sperdouli
submission deadline 28 Feb 2026 | Viewed by 79 | Submission Open
Keywords: light quality and quantity; photoprotection; photoinhibition; chlorophyll; photoreceptors; abiotic stress; antioxidant defense; hormonal interactions; growth responses
(This special issue belongs to the Section Plant Science)
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