Special Issues

Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antibiotic Treatment on Surgical Infections
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 14998 | Submission Open
Keywords: surgical site; infection; emergency surgery; prevention
Inappropriate Use of Antibiotics in Pediatrics
edited by Brian R. Lee
submission deadline 31 Dec 2025 | 4 articles | Viewed by 14669 | Submission Open
Keywords: antimicrobial stewardship; inappropriate antibiotic prescription; antimicrobial resistance; pediatrics
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antimicrobial Resistance in the Community Setting: The Other Side of the Coin
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 13594 | Submission Open
Keywords: emerging resistance; multidrug resistance; emerging virulence; community setting; Staphylococcus aureus; Enterococcus spp.; Streptococcus spp.; Haemophilus spp.; Moraxella spp.; Mycobacterium spp.; Neisseria spp.; Salmonella spp.; Shigella spp.; Campylobacter spp.; anaerobes; fungi
Natural Peptides to Combat Conventional Antibiotic Resistance submission deadline 31 Dec 2025 | 3 articles | Viewed by 11804 | Submission Open
Keywords: antimicrobial peptide; peptide modification; antibiotic resistance; structure– activity relationship; membrane selectivity; resistant strains
(This special issue belongs to the Section Antimicrobial Peptides)
Advancing the Discovery and Development of New Antibiotics through Drug Repurposing
edited by Songping Huang
submission deadline 31 Dec 2025 | 4 articles | Viewed by 11054 | Submission Open
(This special issue belongs to the Section Novel Antimicrobial Agents)
Biofilms and Urinary Tract Infections submission deadline 31 Dec 2025 | 1 articles | Viewed by 10055 | Submission Open
(This special issue belongs to the Section Antibiofilm Strategies)
Multitalented Synthetic Antimicrobial Compounds: From Design to Effect submission deadline 31 Dec 2025 | 4 articles | Viewed by 9533 | Submission Open
Keywords: antimicrobial resistance; antibiotic development; the design of antimicrobial compounds; the synthesis of antimicrobial compounds; medicinal chemistry; bioorganic chemistry; antimicrobial properties; the mechanisms of antimicrobial activity; bioinorganic
(This special issue belongs to the Section Novel Antimicrobial Agents)
A One Health Approach to Antimicrobial Resistance, 2nd Edition
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 9272 | Submission Open
Keywords: One Health; antibiotic; antimicrobial resistance; animal; food; environment
Antimicrobial Resistance in Veterinary Science, 2nd Edition
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 7351 | Submission Open
Keywords: AMR; veterinary animals; farm animals; food animals; wild animals; resistance
(This special issue belongs to the Section Antibiotics in Animal Health)
Therapy of Infectious Diseases Among Children and Adults: The Role of Antibiotics in Daily Practice submission deadline 31 Dec 2025 | 5 articles | Viewed by 7048 | Submission Open
Keywords: аntibiotic use among children; аntibiotic use among adults; аntibiotic use among outpatients; аntibiotic use among inpatients; antibiotic resistance; improper antibiotic use; antibiotic quality control
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Molecular Characterization and Antimicrobial Resistance of Pathogens Isolated from Animals
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 6765 | Submission Open
Keywords: antibiotic resistance; molecular biology; microbiology; genomics; multi-drug resistance; One Health; animals
(This special issue belongs to the Section Antibiotics in Animal Health)
Bioactive Natural Products in Antimicrobial Resistance Management submission deadline 31 Dec 2025 | 3 articles | Viewed by 5213 | Submission Open
Keywords: antimicrobials; antimicrobial resistance; bioactive natural products; novel antimicrobial agents; phytochemicals
(This special issue belongs to the Section Plant-Derived Antibiotics)
Antibiotic Stewardship in Ambulatory Care Settings
edited by Mary Elizabeth Sexton and Sharon V. Tsay
submission deadline 31 Dec 2025 | 4 articles | Viewed by 5146 | Submission Open
Keywords: ambulatory antimicrobial stewardship; antimicrobial resistance
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Research Advances in Antimicrobial Stewardship, Residues and Resistance in Veterinary and Environmental Science
edited by Justine S. Gibson and
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4890 | Submission Open
Keywords: antimicrobial resistance (AMR); antimicrobial stewardship (AMS); antimicrobial residues (ARs); diagnostic tools and therapeutics; epidemiology; sustainable AMR mitigation; one health; veterinary sciences
(This special issue belongs to the Section Antibiotics in Animal Health)
The Issue of Multidrug-Resistant Pathogens in Nosocomial Infections, 2nd Edition submission deadline 31 Dec 2025 | 2 articles | Viewed by 4866 | Submission Open
Keywords: antimicrobial resistance; MDR; XDR; DTR; nosocomial infections
Clostridioides difficile Infection, 3rd Edition
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 4211 | Submission Open
Keywords: Clostridioides difficile; Clostridioides difficile infection recurrence; antimicrobial use; host and microbiota interaction; CDI
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Gram-Negative Multidrug-Resistant Pathogens and Their Treatment, 2nd Edition submission deadline 31 Dec 2025 | 2 articles | Viewed by 4185 | Submission Open
Keywords: carbapenemase-producing enterobacteriaceae; multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa; gram-negative bacteria and antibiotic resistance mechanisms; multidrug resistant; extended-spectrum beta-lactamase (ESBL) producers; antibacterial potential of novel compounds; biofilm inhibition strategies; quorum sensing disruption as a therapeutic approach
Antibacterial Utilisation from Different Perspectives: An Effective Tool to Develop and Evaluate Antimicrobial Stewardship Interventions submission deadline 31 Dec 2025 | 1 articles | Viewed by 4097 | Submission Open
Keywords: quality of antibiotic use; scale of antibiotic use; pattern of antibiotic use; prevalence of antibiotic use; specific patient populations; safety of use; antibacterial; antivirals; antifungals; anti-TBC
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Prevention and Antimicrobial Surveillance of Hospital-Associated Infections
edited by Theodouli Stergiopoulou
submission deadline 31 Dec 2025 | 2 articles | Viewed by 3741 | Submission Open
Keywords: infection monitoring; surveillance program; antimicrobial surveillance; healthcare-associated infections
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Global Strategies for Antimicrobial Surveillance: Country, Regional and Global Perspectives
edited by and Gabriel Levy-Hara
submission deadline 31 Dec 2025 | 3 articles | Viewed by 3508 | Submission Open
Keywords: antimicrobial; stewardship; resistance; consumption; use
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Hospital-Associated Infectious Diseases and Antibiotic Therapy
edited by Carola Mauri and
submission deadline 31 Dec 2025 | 2 articles | Viewed by 3454 | Submission Open
Keywords: hospital-associated infectious diseases; epidemiology; treatment; antibiotic stewardship; antimicrobial resistance; multi-drug resistance
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Multidrug-Resistant Pathogens: Genomic Analysis, Resistance Mechanisms, and Clinical Challenges
edited by and Nemanja Stanisavljevic
submission deadline 31 Dec 2025 | 1 articles | Viewed by 3144 | Submission Open
Keywords: multidrug-resistant pathogens; genomic analysis; antimicrobial resistance; resistance mechanisms; antimicrobial therapy challenges; new antimicrobial drugs and therapies; clinical antimicrobial guidelines
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Tackling Multidrug-Resistant Bacteria with New Antimicrobial Strategies
edited by and
submission deadline 31 Dec 2025 | 2 articles | Viewed by 3117 | Submission Open
Keywords: multidrug-resistant (MDR); antimicrobial resistance (AMR); novel antibiotics; drug discovery; AMR surveillance; epidemiology
(This special issue belongs to the Section Novel Antimicrobial Agents)
Recent Advances in Efflux Pump Inhibitors and Their Role in Combatting Multidrug Resistance submission deadline 31 Dec 2025 | 1 articles | Viewed by 2892 | Submission Open
Keywords: multidrug resistance; multidrug efflux pump; efflux pump inhibitor (EPI); accumulation assay; efflux assay; fluorochromes; ethidium bromide; quorum sensing; biofilm
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Origins and Evolution of Antibiotic Resistance in the Environment submission deadline 31 Dec 2025 | 2 articles | Viewed by 2885 | Submission Open
Keywords: surface water; soil; wastewater; antibiotic resistance genes; antibiotic resistant bacteria; One Health; WHO pathogens; anthropogenic pressure
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Biofilm-Associated Oral Diseases: Advances in Diagnosis and Challenges in Treatment
edited by and Cher Farrugia
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2760 | Submission Open
Keywords: oral diseases; oral biofilms; host– biofilm interactions; novel antimicrobial strategies; molecular dynamics
(This special issue belongs to the Section Antibiofilm Strategies)
Antibiotic Bans and Antimicrobial Resistance: Progress, Challenges, and Future Strategies
edited by and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 2595 | Submission Open
Keywords: impact of antibiotic bans; antibiotic use; antimicrobial resistance; antibiotic restrictions
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Impact of Antibiotic Residues in Wastewater
edited by Jose Sanchez-Salas
submission deadline 31 Dec 2025 | 1 articles | Viewed by 2496 | Submission Open
Keywords: antibiotic residues; wastewater treatment; environmental antibiotics; pharmaceutical contaminants; antimicrobial resistance
Veterinary Antibiotics in Food-Producing Animals: Residue Detection, Risk Assessment and Regulatory Advances submission deadline 31 Dec 2025 | 3 articles | Viewed by 2481 | Submission Open
Keywords: veterinary drugs; analytical chemistry; food safety; risk assessment; regulatory frameworks
(This special issue belongs to the Section Antibiotics in Animal Health)
Antimicrobial Extracts and Compounds Derived from Plants
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1904 | Submission Open
Keywords: antibacterial; antifungal; plant extract; plant compounds; antibiotic-resistant strains; virulence factors; synergistic interactions
(This special issue belongs to the Section Plant-Derived Antibiotics)
Repositioning Drugs as a Strategy to Combat Infections submission deadline 31 Dec 2025 | 1 articles | Viewed by 1834 | Submission Open
Keywords: repositioning drugs; efflux pump inhibitors; resistant microorganisms; microbial biofilm; antibacterial resistance; antifungal potential
(This special issue belongs to the Section The Global Need for Effective Antibiotics)
Foodborne Pathogens: Detection, Resistance Mechanisms, and Control Strategies
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1692 | Submission Open
Keywords: foodborne pathogens; antimicrobial resistance; rapid detection methods; control strategies; food safety interventions; One Health
Antimicrobial Resistance from a One Health Perspective submission deadline 31 Dec 2025 | 1 articles | Viewed by 1471 | Submission Open
Keywords: antimicrobial resistance mechanisms; bacterial virulence; clonal diversity; molecular epidemiology; antibiotic use; infectious diseases; One Health
New Insights Toward the Development of Novel Inhibitors of S. aureus and P. aeruginosa Factors
edited by Que Chi Truong-Bolduc, Leon G. Leanse, and
submission deadline 31 Dec 2025 | 2 articles | Viewed by 1471 | Submission Open
Keywords: MSSA; MRSA; P. aeruginosa; coinfection; antibiotic resistance; therapeutic strategy; anti-virulence; quorum-sensing; virulence factors; biofilms
(This special issue belongs to the Section Novel Antimicrobial Agents)
Antibacterial Treatment in Periodontal and Endodontic Therapy, 3rd Edition
edited by and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1460 | Submission Open
Keywords: periodontology; endodontology; cariology; photodynamics; laser dentistry
ESKAPEE: Mechanisms, Spread, and Evolution of Antimicrobial Resistance
edited by Ning Dong and Yarong Wu
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1316 | Submission Open
Keywords: ESKAPE pathogens; antimicrobial resistance; genomic epidemiology
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Genomic Insights into Dissemination of Multi-Drug Resistance Pathogens submission deadline 31 Dec 2025 | 1 articles | Viewed by 1233 | Submission Open
Keywords: antimicrobial resistance; genomic surveillance; MDR; gene transfer; One Health
Innovative Treatments for Hospital-Acquired Multidrug-Resistant Bacterial Infections
edited by , , Hugo Vigerelli and Florence Carrouel
submission deadline 31 Dec 2025 | 1 articles | Viewed by 964 | Submission Open
Keywords: antimicrobial agents; gram-negative aerobic rods and cocci; vancomycin resistance; cross-infection; infection control
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Gram-Negative Infections in Humans and Companion Animals: A Global Threat
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 831 | Submission Open
Keywords: antimicrobial resistance; Gram-negative infections; humans; companion animals; essential oils; nanoparticles; pro-biotics; antimicrobial peptides; genomics; metagenomics
(This special issue belongs to the Section The Global Need for Effective Antibiotics)
Combatting Dental Infections: Insights into Oral Microbiota and Antibiotic Therapy
edited by and
submission deadline 31 Dec 2025 | Viewed by 767 | Submission Open
Keywords: oral microbiota; dental diseases; systematic disease; antimicrobial; therapeutic strategies; oral biomaterials; oral probiotics; infectious disease; oral microecology; targets
Bacterial Extracellular Vesicles: Vehicles for Pathogenesis and Antibiotic Resistance
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 755 | Submission Open
Keywords: bacterial extracellular vesicles (BEVs); outer membrane vesicles (OMVs); antibiotic resistance; pathogenesis; host-pathogen interaction
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Antibiotic Resistance in Agricultural Environments: Emergence, Drivers and Mitigation
edited by and Juan Wang
submission deadline 31 Dec 2025 | 1 articles | Viewed by 670 | Submission Open
Keywords: antibiotic resistance (AMR); animal husbandry; environmental resistome; livestock microbiome; co-selection; agricultural environments; One Health; antibiotic resistance genes (ARGs); heavy metals; selective pressures
(This special issue belongs to the Section Antibiotics in Animal Health)
Carbapenem-Resistant Acinetobacter baumannii: From Molecular Mechanisms to Clinical Practice
edited by , David L. Paterson and Luca Pipitò
submission deadline 31 Dec 2025 | Viewed by 603 | Submission Open
Keywords: CRAB; XDR; MDR; Acinetobacter baumannii; antimicrobial resistance; molecular mechanisms; clinical practice
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Epidemiology, Impact and Mitigation of Antimicrobial Resistance in Veterinary Medicine, 3rd Edition
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 577 | Submission Open
Keywords: antimicrobial resistance; veterinary medicine; antibiotics; One Health; epidemiology
The One Health Perspective: Unveiling Animal and Zoonotic Microbiota in the Frame of Antimicrobial Resistance submission deadline 31 Dec 2025 | 1 articles | Viewed by 484 | Submission Open
Keywords: antimicrobial resistance (AMR); One Health approach; veterinary medicine; livestock production; foodborne pathogen reservoirs; epidemiological mapping; resistance mechanisms; microbiome; resistome; intervention
(This special issue belongs to the Section Antibiotics in Animal Health)
Phage Therapy and Antimicrobial Innovation
edited by Ronen Hazan and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 439 | Submission Open
Keywords: antimicrobial resistance (AMR); antimicrobial innovation; phage therapy; phage engineering; synergistic strategies; chronic infections; biofilm; clinical phage microbiology; personalized medicine
(This special issue belongs to the Section Bacteriophages)
Natural Compounds as Antimicrobial Agents, 3rd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 383 | Submission Open
Keywords: new natural antimicrobial compounds; antimicrobial effects; clinical applications; animal production applications; antifungal properties; antiviral properties; food applications; new formulations; antibacterial mechanisms; antifungal mechanisms; MICs; activity as disinfectants; activity against biofilms; effects on transcriptomics; combination with other antimicrobials; global microbiome changes
(This special issue belongs to the Section Novel Antimicrobial Agents)
Global Trends in Antimicrobial Resistance: Epidemiology and Public Health Implications
edited by Louise Teixeira Cerdeira
submission deadline 31 Dec 2025 | Viewed by 354 | Submission Open
Keywords: antimicrobial resistance (AMR); antibiotic misuse; global health; epidemiology; antibiotic stewardship
(This special issue belongs to the Section The Global Need for Effective Antibiotics)
Global Perspectives on Antimicrobial Stewardship and Food Safety
edited by
submission deadline 31 Dec 2025 | Viewed by 342 | Submission Open
Keywords: antimicrobial resistance; antimicrobial use; food systems; food safety; antimicrobial stewardship
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antimicrobial Resistance in the Wildlife
edited by and Giuliana Siddi
submission deadline 31 Dec 2025 | Viewed by 320 | Submission Open
Keywords: wildlife; wild animal; antimicrobial resistance; transmission; spread; One Health
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