ESKAPEE: Mechanisms, Spread, and Evolution of Antimicrobial Resistance
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Mechanism and Evolution of Antibiotic Resistance".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 810
Special Issue Editors
Interests: antimicrobial resistance; genomic epidemiology of infectious agents; One Health; drug discovery
Interests: population genomics of bacteria; bacterial evolution
Special Issue Information
Dear Colleagues,
ESKAPE consists of six bacterial pathogens that contribute to a considerable amount of antibiotic-resistant infections identified in clinical medicine, including Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. These highly virulent and antibiotic-resistant ESKAPE pathogens are the leading cause of nosocomial infection around the globe, particularly among critically ill and immunocompromised individuals. Their capacity to harbor intrinsic or acquired resistance determinants under both natural and anthropogenic selective pressures has led to the widespread emergence of multidrug-resistant strains, enabling these bacteria to evade or withstand conventional antibiotic therapies. Consequently, infections caused by ESKAPE pathogens are frequently associated with limited treatment options, higher risks of therapeutic failure, and increased morbidity and mortality. The growing burden of these infections imposes significant challenges on healthcare systems, necessitating urgent efforts to develop more effective strategies for prevention, diagnosis, and treatment.
This Special Issue aims to provide an in-depth discussion of the mechanisms of resistance among ESKAPE pathogens and the spread and evolution of such pathogens, integrating insights from molecular microbiology, evolutionary biology, and epidemiology. It critically examines the genetic determinants, biochemical pathways, and adaptive strategies that underpin the emergence and dissemination of antimicrobial resistance. Through rigorous scientific analysis, this collection of articles hopes to enhance the understanding of the epidemiological dynamics of ESKAPE pathogens and to inform effective clinical practices and public health policies.
Dr. Ning Dong
Dr. Yarong Wu
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- ESKAPE pathogens
- antimicrobial resistance
- genomic epidemiology
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
