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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Research Advances in Antimicrobial Stewardship, Residues and Resistance in Veterinary and Environmental Science

edited by Justine S. Gibson and

Ricardo J. Soares Magalhães

submission deadline 10 Sep 2026 | 3 articles | Viewed by 9196 | Submission Open

Keywords: antimicrobial resistance (AMR); antimicrobial stewardship (AMS); antimicrobial residues (ARs); diagnostic tools and therapeutics; epidemiology; sustainable AMR mitigation; one health; veterinary sciences

(This special issue belongs to the Section Antibiotics in Animal Health)

Nature-Inspired Scaffolds as Antimicrobial Hits in the AMR Era: Microbial Pathways, Biofilms and Resistance

edited by

Francesca Bonvicini

and

Alessandra Bisi

submission deadline 10 Sep 2026 | Viewed by 316 | Submission Open

Keywords: antimicrobial resistance (AMR); biofilm-related infections; nature-inspired scaffolds; hit-to-lead optimization; antibiofilm agents; anti-virulence agents; quorum sensing quenching agents

(This special issue belongs to the Section Novel Antimicrobial Agents)

Surveillance of Carbapenem-Resistant Microbes and Strategies to Combat Them

edited by Daniela Cejas and Marcela Radice

submission deadline 15 Sep 2026 | 3 articles | Viewed by 4321 | Submission Open

Keywords: antibiotic resistance; epidemiology; carbapenemases; carbapenem resistance; enterobacterales; acinetobacter baumannii; resistance plasmids; surveillance; genomics; high-risk clones

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Stewardship in Surgical Infection

edited by Nuno Rocha-Pereira

submission deadline 20 Sep 2026 | 6 articles | Viewed by 9806 | Submission Open

Keywords: antimicrobial stewardship; surgical infection; surgical site infection; antimicrobial resistance; diagnostic stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Hospital-Acquired Infections, Multidrug Resistant (MDR) Bacteria, AI, and Alternative Approaches to Antibiotic Therapy

edited by

Susu Zughaier

and

Nayeem Ahmad

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1200 | Submission Open

Keywords: antimicrobial resistance; hospital-acquired infections; multidrug resistant; artificial intelligence; nosocomial infection; molecular mechanism of resistant bacteria

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Inappropriate Use of Antibiotics in Pediatrics

edited by Brian R. Lee

submission deadline 30 Sep 2026 | 8 articles | Viewed by 28116 | Submission Open

Keywords: antimicrobial stewardship; inappropriate antibiotic prescription; antimicrobial resistance; pediatrics

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Resistance and Infections in Veterinary Settings

edited by Hatem Kittana and Tamara Gull

submission deadline 30 Sep 2026 | 4 articles | Viewed by 24921 | Submission Open

Keywords: veterinary medicine; antibiotics; antimicrobial resistance; infectious microorganims; food-producing animals; companion aniamls

(This special issue belongs to the Section Antibiotics in Animal Health)

Genomic Analysis of Drug-Resistant Pathogens

edited by

Erica Diani

submission deadline 30 Sep 2026 | 3 articles | Viewed by 22317 | Submission Open

Keywords: multi-drug resistant; mutation; bacteria; NGS; sequencing; mobile genetics elements; gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibacterial and Antibiofilm Properties of Biomaterial

edited by

Ziba Najmi

and Alessandro Calogero Scalia

submission deadline 30 Sep 2026 | 3 articles | Viewed by 12979 | Submission Open

Keywords: biomaterials surfaces; coating; biofilm formation; biofilm eradication

(This special issue belongs to the Section Antibiofilm Strategies)

Genomic Insights and Implications of Emerging Antimicrobial Resistance

edited by

Daniela Bencardino

and

Christian Berens

submission deadline 30 Sep 2026 | 6 articles | Viewed by 12844 | Submission Open

Keywords: antibiotic-resistance; molecular typing; genomic technologies; high-threat pathogens; epidemiological surveillance; emerging and re-emerging infectious diseases; one health approach

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Molecular Characterization and Antimicrobial Resistance of Pathogens Isolated from Animals

edited by

Isabel Carvalho

submission deadline 30 Sep 2026 | 3 articles | Viewed by 11147 | Submission Open

Keywords: antibiotic resistance; molecular biology; microbiology; genomics; multi-drug resistance; One Health; animals

(This special issue belongs to the Section Antibiotics in Animal Health)

Single-Stage Management of Musculo-Skeletal Infections: Local Antibacterial Protection, Antibiotics, and Surgical Treatments

edited by

Carlo L. Romanò

submission deadline 30 Sep 2026 | 3 articles | Viewed by 10841 | Submission Open

Keywords: knee arthroplasty; hip arthroplasty; shoulder arthroplasty; antibiotic treatment; one-stage revision arthroplasty; antibacterial coating

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Stewardship—from Projects to Standard of Care

edited by Gesche Först and Franky Buyle

submission deadline 30 Sep 2026 | 5 articles | Viewed by 10772 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial use; antibiotics; implementation; efficacy; quality; antimicrobial prescribing

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Veterinary Antibiotics in Food-Producing Animals: Residue Detection, Risk Assessment and Regulatory Advances

edited by

Liliana J.G. Silva

and

Marta Leite

submission deadline 30 Sep 2026 | 6 articles | Viewed by 10310 | Submission Open

Keywords: veterinary drugs; analytical chemistry; food safety; risk assessment; regulatory frameworks

(This special issue belongs to the Section Antibiotics in Animal Health)

Hospital-Associated Infectious Diseases and Antibiotic Therapy

edited by Carola Mauri and

Alessandra Consonni

submission deadline 30 Sep 2026 | 2 articles | Viewed by 10212 | Submission Open

Keywords: hospital-associated infectious diseases; epidemiology; treatment; antibiotic stewardship; antimicrobial resistance; multi-drug resistance

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Prevention and Antimicrobial Surveillance of Hospital-Associated Infections

edited by Theodouli Stergiopoulou

submission deadline 30 Sep 2026 | 6 articles | Viewed by 9282 | Submission Open

Keywords: infection monitoring; surveillance program; antimicrobial surveillance; healthcare-associated infections

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Urinary Tract Infections: Diagnosis, Etiology, Antibiotic Treatment, and Current Trends in Antimicrobial Resistance

edited by Michael Mihailov Petrov

submission deadline 30 Sep 2026 | 6 articles | Viewed by 8194 | Submission Open

Keywords: urinary tract infections (UTIs); etiology; epidemiology; microbiological diagnosis; antimicrobial resistance; treatment; molecular genetic methods; resistotypes; rapid identification; uropathogens

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

New Advances in Antibiotic Therapy in the Gastroenterology Field

edited by

Giuseppe Guido Maria Scarlata

and Francesca Serapide

submission deadline 30 Sep 2026 | 4 articles | Viewed by 6589 | Submission Open

Keywords: antibiotic therapy; antimicrobial resistance; gastroenterology; infectious diseases; microbiology; gut–liver axis; antimicrobial stewardship; infection control; biomarkers; diagnosis; epidemiology

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Current Advances and Innovations in Anti-Infective Agents Discovery

edited by

Valnês da Silva Rodrigues-Junior

submission deadline 30 Sep 2026 | 4 articles | Viewed by 5621 | Submission Open

Keywords: drug development; antiviral; antibacterial; antifungal; antiparasitic

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotics for Primary Care Practice

edited by Reza Nassiri

submission deadline 30 Sep 2026 | 2 articles | Viewed by 5301 | Submission Open

Keywords: primary care practice; nursing home practice; remote practice; antibiotic prescription habits; antibiotic resistance in clinical practice; public health consequences of antibiotic resistance; antibiotics stewardship practices; elements of safe practice

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Resistance and One Health: Environmental Health, Food Safety, and Practice of Health Professionals

edited by

Teresa Letra Mateus

and

Francisco Cortez Nunes

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4452 | Submission Open

Keywords: antibiotics; antibiotic resistance; guidelines compliance; health communication; One Health; public awareness

Pioneering the Microbiome—Infections, Inflammation, Inflammatory Bowel Disease and the Role of Antibiotic Therapy

edited by

Gaurav Agrawal

and

Roger Pickup

submission deadline 30 Sep 2026 | 1 articles | Viewed by 3812 | Submission Open

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Resistance and Epidemiological Study of Clinically Relevant Pathogens, 2nd Edition

edited by

Florin George Horhat

Adrian Man

and

Delia Muntean

submission deadline 30 Sep 2026 | 4 articles | Viewed by 3395 | Submission Open

Keywords: antibacterial activity; antimicrobial resistance; infections; multidrug-resistant pathogens; virulence gene expression; drug discovery; epidemiological study

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

A Themed Issue in Honor of Professor Stefan Schwarz—Antimicrobial Resistance of Bacteria of Animal Origin: Diagnostics, Monitoring, Mechanisms and Epidemiology

edited by

Igor Loncaric

and Séamus Fanning

submission deadline 30 Sep 2026 | 2 articles | Viewed by 3011 | Submission Open

Keywords: antimicrobial resistance; animals; resistance genes; mechanism of resistance; MRSA; ESBL; staphylococci; enterobacterales

Resistance, Treatment and Prevention of ESKAPE Pathogens

edited by

Steven E. Fiester

and

William Penwell

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2581 | Submission Open

Keywords: antibiotic resistance; prevention methods; treatment strategies; ESKAPE pathogens

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Periprosthetic Joint Infections: Antimicrobial Biomaterials and Antibiotic Treatment

edited by

Konstantinos Anagnostakos

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2579 | Submission Open

Keywords: periprosthetic joint infection (PJI); local antibiotic therapy; systemic antibiotic therapy; bone cement; antibiotic carrier; one-stage treatment; two-stage treatment

Feature Reviews in Mechanism and Evolution of Antibiotic Resistance 2026

edited by

Krisztina M. Papp-Wallace

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2029 | Submission Open

Keywords: antibiotic resistance mechanisms; intrinsic and acquired resistance; antimicrobial selective pressure; bacterial evolutionary dynamics; omics and molecular epidemiology

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Limits and Risks of Quorum Quenching in Medicine

edited by

Emil Paluch

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1860 | Submission Open

Keywords: quorum quenching; quorum sensing; biofilm; Pseudomonas aeruginosa; Staphylococcus aureus; antimicrobial resistance; anti-virulence therapy

(This special issue belongs to the Section Novel Antimicrobial Agents)

Genetic Blueprints of Resistance, Persistence and Tolerance: Biochemical and Omic Perspectives on Antibiotic Activity

edited by

Viviana Cafiso

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1763 | Submission Open

Keywords: AMR; persistence; tolerance genetic plasticity; genomics; transcriptomics proteomics; biochemical mechanisms; biomarkers

(This special issue belongs to the Section Genetic and Biochemical Studies of Antibiotic Activity and Resistance)

Bacteriocins and Antimicrobial Peptides in the Era of Antimicrobial Resistance

edited by

Umme Laila Urmi

and

Shyam Kumar Mishra

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1586 | Submission Open

Keywords: bacteriocins; antimicrobial peptides; antimicrobial resistance; multidrug-resistant pathogens; novel therapeutics

Novel Antimicrobials for ESKAPE Pathogens: From Research to Treatment

edited by

Nalin Abeydeera

, Bishnu Pant and

Sara Scutera

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1539 | Submission Open

Keywords: antimicrobial resistance; ESKAPE pathogens; novel antibiotics; metal-based antimicrobials; antibiofilm agents; drug discovery; nanomaterials; host-directed therapy; combination therapy

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Resistance in Neonatal Infections: Challenges and Strategies

edited by

Vasilios Giapros

, Maria Baltogianni and Niki Dermitzaki

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1084 | Submission Open

Keywords: antibiotic resistance; neonatal intensive care unit; neonatal sepsis; antibiotic stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Molecular and Therapeutic Insights into Antimicrobial Candidates and Antibiotics

edited by

Fabio Aguiar Alves

and

Bruno de Araujo Penna

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1053 | Submission Open

Keywords: antimicrobial resistance; novel antimicrobial agents; molecular mechanisms; therapeutic applications

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Resistance Detection and Surveillance

edited by Célia Nogueira

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1029 | Submission Open

Keywords: antimicrobial resistance; resistance gene detection; surveillance systems; molecular diagnostics; One Health; bioinformatics

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Hydrogel Coatings and Bioactive Molecules for Wound Healing and Cosmetic Applications

edited by

Skander Hathroubi

submission deadline 30 Sep 2026 | 1 articles | Viewed by 475 | Submission Open

Keywords: hydrogel-based coatings; hydroge-coated materials; antioxidant ant-inlammatory; antimicrobial peptides; bloactive molecules

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Aquatic AMR Hotspots: Antibiotic Contamination, Resistance Gene Flow, and Environmental Reservoirs

edited by

Ertugrul Terzi

submission deadline 30 Sep 2026 | Viewed by 362 | Submission Open

Keywords: aquatic environment; multidrug-resistant bacteria; plasmids; horizontal gene transfer; mobile genetic elements; antimicrobial resistance genes; MAR index

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Therapeutic Drug Monitoring for Antimicrobial Agents

edited by

Dario Cattaneo

and

Giammarco Baiardi

submission deadline 30 Sep 2026 | Viewed by 323 | Submission Open

Keywords: therapeutic drug monitoring; antibiotics; antifungal agents; pharmacokinetics; pharmacodynamics; drug-drug interactions; bioanalytical techiques

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Innovative Drug Development for Combating Antibiotic Resistance

edited by

Zeinab Khalil

submission deadline 30 Sep 2026 | Viewed by 260 | Submission Open

Keywords: antibiotic resistance; antimicrobial drug discovery; β-lactamases; efflux pumps; biofilms and persistence; adjuvant/combination therapy; anti-virulence strategies; bacteriophage therapy; AI-enabled antibiotic design

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotic Resistance and Antimicrobial Use in Pediatric Wards

edited by

Evanthia Botsa

and

Spyridon Karageorgos

submission deadline 1 Oct 2026 | Viewed by 438 | Submission Open

Keywords: antimicrobial resistance (AMR); pediatric infectious diseases; hospital-acquired infections; antimicrobial stewardship; multidrug-resistant organisms (MDROs); diagnostic innovations in pediatrics

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Advances in the Field of Biofilm-Associated Musculoskeletal Infections

edited by

Kordo Saeed

submission deadline 10 Oct 2026 | 5 articles | Viewed by 23731 | Submission Open

Keywords: musculoskeletal infections; biofilm-associated; mycobacterial-associated; implant-related infections

(This special issue belongs to the Section Antibiofilm Strategies)

Antibiotic Prophylaxis and Stewardship in Surgical Infection

edited by

Arda Isik

submission deadline 10 Oct 2026 | 1 articles | Viewed by 1629 | Submission Open

Keywords: surgical site infection; antibiotic prophylaxis; antimicrobial stewardship; postoperative infection; perioperative care; infection control; antibiotic resistance; surgical outcomes

Antibiotic Resistance: The Role of Aquatic Environments

edited by

Jason W. Marion

and Matthew D. Stocker

submission deadline 15 Oct 2026 | 3 articles | Viewed by 7850 | Submission Open

Keywords: antibiotic resistance; water; wastewater; One Health; antibiotic misuse; antimicrobial resistance genes; microbiology; fecal indicator bacteria; mobile genetic elements; resistome; pollution; environment; water bodies; water treatment; waterborne disease; public health; risk assessment; sanitation; hygiene; aquatic environments

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Resistance in Hospital-Acquired Infections, 2nd Edition

edited by Andreea-Loredana Golli and

Ovidiu Zlatian

submission deadline 15 Oct 2026 | 1 articles | Viewed by 1401 | Submission Open

Keywords: healthcare-associated infections; multi-drug resistance; epidemiology; antimicrobial therapy; patient outcomes; infection prevention and control strategies

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Resistance: A One-Health Approach, 3rd Edition

edited by

Piera Anna Martino

submission deadline 20 Oct 2026 | Viewed by 335 | Submission Open

Keywords: antibiotic-resistance; One Health; virulence factors; genomics; novel natural molecules; antimicrobial stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Phage-Based Biotechnologies for Targeted Bacterial Control: From Phage Biology to Sustainable Applications

edited by

Jaime Romero

submission deadline 30 Oct 2026 | 1 articles | Viewed by 2161 | Submission Open

Keywords: bacteriophages; targeted bacterial control; phage-based biotechnologies; phage–host interactions; endolysins and phage-derived enzymes; antimicrobial alternatives; microbial ecology; sustainable biocontrol; phage engineering

(This special issue belongs to the Section Bacteriophages)

Antibiotic Stewardship Implementation Strategies

edited by

Massimo Sartelli

submission deadline 31 Oct 2026 | 9 articles | Viewed by 14261 | Submission Open

Keywords: antibiotic stewardship; implementation; hospital settings

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Bioactive Natural Products in Antimicrobial Resistance Management

edited by

Ljubiša Šarić

Zorica Tomičić

and

Ružica Tomičić

submission deadline 31 Oct 2026 | 4 articles | Viewed by 13641 | Submission Open

Keywords: antimicrobials; antimicrobial resistance; bioactive natural products; novel antimicrobial agents; phytochemicals

(This special issue belongs to the Section Plant-Derived Antibiotics)

Mechanisms of Microbial Biofilm Resistance and New Methods for Biofilm Control

edited by

Gianmarco Mangiaterra

submission deadline 31 Oct 2026 | 4 articles | Viewed by 11643 | Submission Open

Keywords: quorum sensing; chronic infections; antibiotic resistance; persistence; efflux pumps

(This special issue belongs to the Section Antibiofilm Strategies)

Antibiotic Therapy in Respiratory Tract Infections (RTIs)

edited by Ágnes Tóth and

Attila Csaba Nagy

submission deadline 31 Oct 2026 | 4 articles | Viewed by 10910 | Submission Open

Keywords: antibiotic therapy; respiratory tract infections; clinical guidelines; prescribing practices; antibacterial resistance; antimicrobial stewardship

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Biofilm-Associated Oral Diseases: Advances in Diagnosis and Challenges in Treatment

edited by