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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Streptococcus spp. Research: Pathogenicity, Resistance, and Clinical Implications

edited by

Prescilla Emy Nagao

and

Louisy Sanches Dos Santos

submission deadline 30 Nov 2025 | Viewed by 37 | Submission Open

Keywords: Streptococcus; Corynebacterium; epidemiology; virulence; antimicrobial resistance

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Resistance and Antimicrobial Stewardship in Veterinary Medicine

edited by Tiana Florea,

Ilie Stelian

and

Degi Janos

submission deadline 30 Nov 2025 | Viewed by 30 | Submission Open

Keywords: antimicrobial stewardship; antibiotics; animals; sustainability; drugs; antimicrobial resistance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Small Intestinal Bacterial Overgrowth and Antimicrobials

edited by

Mislav Radić

and

Andrej Belančić

submission deadline 30 Nov 2025 | Viewed by 30 | Submission Open

Keywords: small intestine bacterial overgrowth; antibiotics; probiotics; gut microbiome

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Prescribing, Population Use and Resistance, Impact in Global Health, 3rd Edition

edited by

Juan Manuel Vázquez-Lago

Ana Estany-Gestal

and

Angel Salgado-Barreira

submission deadline 30 Nov 2025 | Viewed by 29 | Submission Open

Keywords: epidemiology; social behavior; antibiotic resistance; social factors; attitudes; knowledge; practice; qualitative research; public health interventions; antibiotic prescription; community care

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Surveillance and Molecular Diagnosis of Antimicrobial-Resistant Pathogens: From Laboratory to Clinical Practice

edited by Neena Kanwar

submission deadline 5 Dec 2025 | Viewed by 44 | Submission Open

Keywords: clinical microbiology; molecular diagnostics; infectious disease epidemiology; antimicrobial susceptibility; microbial culture

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Urinary Tract Infections and Antibiotic Intervention, 2nd Edition

edited by

Majid Mirzazadeh

submission deadline 10 Dec 2025 | Viewed by 264 | Submission Open

Keywords: UTI; antibiotic; microbiome; PCR; next-generation sequencing; urine culture; enhanced quantitative urine cultures; urinary sepsis

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

The Spread of Antibiotic Resistance in Natural Environments

edited by

Daniel Gyamfi Amoako

submission deadline 15 Dec 2025 | 3 articles | Viewed by 8469 | Submission Open

Keywords: antibiotic resistance dissemination; antibiotic pollution; environmental adaptation; mobile genetic elements; ecological impact; environmental microbiome; resistance gene transfer; resistance hotspot; genomic landscape; One Health approach; emerging contaminants; bioinformatics in environmental genomics

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Resistance and Environmental Health, 2nd Edition

edited by

Akebe Luther King Abia

submission deadline 15 Dec 2025 | 1 articles | Viewed by 1826 | Submission Open

Keywords: public health; environmental health; antibiotic resistance; environmental resistome; antibiotic-resistant bacteria; whole-genome sequencing; metagenomics; climate change and AMR; AMR models and One Health

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Challenges of Antibiotic Resistance: Biofilms and Anti-Biofilm Agents

edited by

María Melissa Gutiérrez-Pacheco

and

Luis Alberto Ortega-Ramirez

submission deadline 20 Dec 2025 | Viewed by 367 | Submission Open

Keywords: antibiotic resistance; biofilms; quorum sensing; virulence factors; resistance mechanisms; antibiofilm agents; natural compounds; synthetic drugs

(This special issue belongs to the Section Antibiofilm Strategies)

Antibiotic Surveillance and Rational Use in Special Populations: Enhancing Stewardship for Vulnerable Groups

edited by

Phumzile P Skosana

and

Filippo Mariano

submission deadline 20 Dec 2025 | Viewed by 102 | Submission Open

Keywords: antibiotic stewardship; surveillance systems; special populations; rational use of antibiotics; infectious disease management

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Environmental Risk and Antibiotic Resistance in Hospital-Acquired Infections

edited by

Catherine Neuwirth

submission deadline 20 Dec 2025 | Viewed by 36 | Submission Open

Keywords: nosocomial outbreak; environmental reservoir; investigation; corrective actions; short- and long-term outcomes

Phage Applications from Diagnostics to Treatment of Bacterial Infections in a One Health World

edited by

Mariagrazia Di Luca

and

Goran Vukotic

submission deadline 31 Dec 2025 | 8 articles | Viewed by 22685 | Submission Open

Keywords: phage therapy; antibiotic resistance; bacteriophages; regulatory framework; veterinary medicine; agriculture treatment; aquaculture

(This special issue belongs to the Section Bacteriophages)

Epidemiology and Mechanism of Bacterial Resistance to Antibiotics

edited by

Gabriela Loredana Popa

and

Mircea Ioan Popa

submission deadline 31 Dec 2025 | 9 articles | Viewed by 19603 | Submission Open

Keywords: multi-drug resistant (MDR); classic and molecular epidemiology; plasmids; resistance gene

Bacterial Detection, Identification, and Antimicrobial Susceptibility Testing

edited by

Gabriele Bianco

submission deadline 31 Dec 2025 | 7 articles | Viewed by 19501 | Submission Open

Keywords: identification methods; rapid diagnostics; MALDI-TOF MS; molecular testing; rapid antimicrobial susceptibility testing; antimicrobial susceptibility; synergy testing; β -lactam/β -lactamase inhibitor; fosfomycin; colistin

Antibiotic Resistance: A One-Health Approach, 2nd Edition

edited by

Piera Anna Martino

submission deadline 31 Dec 2025 | 8 articles | Viewed by 16846 | Submission Open

Keywords: antibiotic-resistance; One Health; virulence factors; genomics; novel natural molecules; antimicrobial stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Advancing the Discovery and Development of New Antibiotics through Drug Repurposing

edited by Songping Huang

submission deadline 31 Dec 2025 | 4 articles | Viewed by 8773 | Submission Open

(This special issue belongs to the Section Novel Antimicrobial Agents)

Preventing Antimicrobial Resistance in Hospitals: Infection Control and Antibiotic Use

edited by Dorota Pastuszak-Lewandoska,

Filip Bielec

and Małgorzata Brauncajs

submission deadline 31 Dec 2025 | 6 articles | Viewed by 7460 | Submission Open

Keywords: clinical antibiotic use; hospital infection control; healthcare-associated infections; resistance mitigation strategies; alternative therapies; antibiotic stewardship; molecular mechanisms of AMR; new therapeutic combinations of antibiotics; antimicrobial synergy

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Multitalented Synthetic Antimicrobial Compounds: From Design to Effect

edited by

Tsz Tin Yu

and

Maria Fernanda N. N. Carvalho

submission deadline 31 Dec 2025 | 4 articles | Viewed by 6426 | Submission Open

Keywords: antimicrobial resistance; antibiotic development; the design of antimicrobial compounds; the synthesis of antimicrobial compounds; medicinal chemistry; bioorganic chemistry; antimicrobial properties; the mechanisms of antimicrobial activity; bioinorganic

(This special issue belongs to the Section Novel Antimicrobial Agents)

Bacteriophage Therapy a Renaissance Weapon Recent Developments and Application, 2nd Edition

edited by

Aneta Skaradzińska

and

Paulina Śliwka

submission deadline 31 Dec 2025 | 4 articles | Viewed by 5286 | Submission Open

Keywords: bacteriophages; phage therapy; application of phages; antibiotic-resistance; antibacterial therapies

(This special issue belongs to the Section Bacteriophages)

Molecular Characterization and Antimicrobial Resistance of Pathogens Isolated from Animals

edited by

Isabel Carvalho

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4326 | Submission Open

Keywords: antibiotic resistance; molecular biology; microbiology; genomics; multi-drug resistance; One Health; animals

(This special issue belongs to the Section Antibiotics in Animal Health)

Antimicrobial Resistance in Veterinary Science, 2nd Edition

edited by

Nahla O. Eltai

submission deadline 31 Dec 2025 | 4 articles | Viewed by 4206 | Submission Open

Keywords: AMR; veterinary animals; farm animals; food animals; wild animals; resistance

(This special issue belongs to the Section Antibiotics in Animal Health)

Antimicrobial Activity of Plants Against Emerging or Drug-Resistant Human Pathogens

edited by

Andrés H. Uc-Cachón

and

Gloria María Molina-Salinas

submission deadline 31 Dec 2025 | 4 articles | Viewed by 3402 | Submission Open

Keywords: anti-infective agents; antimicrobial activity; human pathogens; medicinal plants; natural products; phytodrugs

(This special issue belongs to the Section Plant-Derived Antibiotics)

Research Advances in Antimicrobial Stewardship, Residues and Resistance in Veterinary and Environmental Science

edited by Justine S. Gibson and

Ricardo J. Soares Magalhães

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2760 | Submission Open

Keywords: antimicrobial resistance (AMR); antimicrobial stewardship (AMS); antimicrobial residues (ARs); diagnostic tools and therapeutics; epidemiology; sustainable AMR mitigation; one health; veterinary sciences

(This special issue belongs to the Section Antibiotics in Animal Health)

The Issue of Multidrug-Resistant Pathogens in Nosocomial Infections, 2nd Edition

edited by

Alberto Enrico Maraolo

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2245 | Submission Open

Keywords: antimicrobial resistance; MDR; XDR; DTR; nosocomial infections

The One Health Action Plan Against Antimicrobial Resistance

edited by

Anna Maria Spagnolo

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2177 | Submission Open

Keywords: one health approach; antimicrobial resistance; healthcare-associated infections; food contamination; environment and antibiotic resistance; surveillance; prevention and control

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Clostridioides difficile Infection, 3rd Edition

edited by

Guido Granata

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1962 | Submission Open

Keywords: Clostridioides difficile; Clostridioides difficile infection recurrence; antimicrobial use; host and microbiota interaction; CDI

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Stewardship in Ambulatory Care Settings

edited by Mary Elizabeth Sexton and Sharon V. Tsay

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1772 | Submission Open

Keywords: ambulatory antimicrobial stewardship; antimicrobial resistance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Bans and Antimicrobial Resistance: Progress, Challenges, and Future Strategies

edited by

Abdelaziz Ed-Dra

and

Min Yue

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1515 | Submission Open

Keywords: impact of antibiotic bans; antibiotic use; antimicrobial resistance; antibiotic restrictions

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Bioactive Natural Products in Antimicrobial Resistance Management

edited by

Ljubiša Šarić

Zorica Tomičić

and

Ružica Tomičić

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1134 | Submission Open

Keywords: antimicrobials; antimicrobial resistance; bioactive natural products; novel antimicrobial agents; phytochemicals

(This special issue belongs to the Section Plant-Derived Antibiotics)

Therapy of Infectious Diseases Among Children and Adults: The Role of Antibiotics in Daily Practice

edited by

Magdalena Baymakova

and

Valeri R. Velev

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1084 | Submission Open

Keywords: аntibiotic use among children; аntibiotic use among adults; аntibiotic use among outpatients; аntibiotic use among inpatients; antibiotic resistance; improper antibiotic use; antibiotic quality control

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Repositioning Drugs as a Strategy to Combat Infections

edited by

Hélcio Silva Dos Santos

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1025 | Submission Open

Keywords: repositioning drugs; efflux pump inhibitors; resistant microorganisms; microbial biofilm; antibacterial resistance; antifungal potential

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Biofilm-Associated Oral Diseases: Advances in Diagnosis and Challenges in Treatment

edited by

Naiera Zayed

and Cher Farrugia

submission deadline 31 Dec 2025 | 1 articles | Viewed by 649 | Submission Open

Keywords: oral diseases; oral biofilms; host– biofilm interactions; novel antimicrobial strategies; molecular dynamics

(This special issue belongs to the Section Antibiofilm Strategies)

Combatting Dental Infections: Insights into Oral Microbiota and Antibiotic Therapy

edited by

Biao Ren

and

Jaya Seneviratne

submission deadline 31 Dec 2025 | Viewed by 474 | Submission Open

Keywords: oral microbiota; dental diseases; systematic disease; antimicrobial; therapeutic strategies; oral biomaterials; oral probiotics; infectious disease; oral microecology; targets

Antibacterial Treatment in Periodontal and Endodontic Therapy, 3rd Edition

edited by

Andreas Braun

and

Felix Krause

submission deadline 31 Dec 2025 | 1 articles | Viewed by 468 | Submission Open

Keywords: periodontology; endodontology; cariology; photodynamics; laser dentistry

Tackling Multidrug-Resistant Bacteria with New Antimicrobial Strategies

edited by

Vivek Keshri

and

Marc Maresca

submission deadline 31 Dec 2025 | Viewed by 343 | Submission Open

Keywords: multidrug-resistant (MDR); antimicrobial resistance (AMR); novel antibiotics; drug discovery; AMR surveillance; epidemiology

(This special issue belongs to the Section Novel Antimicrobial Agents)

Global Perspectives on Antimicrobial Stewardship and Food Safety

edited by

Mahmoud Eltholth

submission deadline 31 Dec 2025 | Viewed by 260 | Submission Open

Keywords: antimicrobial resistance; antimicrobial use; food systems; food safety; antimicrobial stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibacterial Utilisation from Different Perspectives: An Effective Tool to Develop and Evaluate Antimicrobial Stewardship Interventions

edited by

Gyöngyvér Soós

and

Ria Benkő

submission deadline 31 Dec 2025 | Viewed by 249 | Submission Open

Keywords: quality of antibiotic use; scale of antibiotic use; pattern of antibiotic use; prevalence of antibiotic use; specific patient populations; safety of use; antibacterial; antivirals; antifungals; anti-TBC

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Foodborne Pathogens: Detection, Resistance Mechanisms, and Control Strategies

edited by

Joana Campos

submission deadline 31 Dec 2025 | Viewed by 247 | Submission Open

Keywords: foodborne pathogens; antimicrobial resistance; rapid detection methods; control strategies; food safety interventions; One Health

Natural Compounds as Antimicrobial Agents, 3rd Edition

edited by

Carlos M. Franco

submission deadline 31 Dec 2025 | Viewed by 243 | Submission Open

Keywords: new natural antimicrobial compounds; antimicrobial effects; clinical applications; animal production applications; antifungal properties; antiviral properties; food applications; new formulations; antibacterial mechanisms; antifungal mechanisms; MICs; activity as disinfectants; activity against biofilms; effects on transcriptomics; combination with other antimicrobials; global microbiome changes

(This special issue belongs to the Section Novel Antimicrobial Agents)

Global Trends in Antimicrobial Resistance: Epidemiology and Public Health Implications

edited by Louise Teixeira Cerdeira

submission deadline 31 Dec 2025 | Viewed by 216 | Submission Open

Keywords: antimicrobial resistance (AMR); antibiotic misuse; global health; epidemiology; antibiotic stewardship

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Hospital-Associated Infectious Diseases and Antibiotic Therapy

edited by Carola Mauri and

Alessandra Consonni

submission deadline 31 Dec 2025 | Viewed by 173 | Submission Open

Keywords: hospital-associated infectious diseases; epidemiology; treatment; antibiotic stewardship; antimicrobial resistance; multi-drug resistance

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

ESKAPEE: Mechanisms, Spread, and Evolution of Antimicrobial Resistance

edited by Ning Dong and Yarong Wu

submission deadline 31 Dec 2025 | Viewed by 149 | Submission Open

Keywords: ESKAPE pathogens; antimicrobial resistance; genomic epidemiology

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Resistance in the Wildlife

edited by

Francesca Piras

submission deadline 31 Dec 2025 | Viewed by 140 | Submission Open

Keywords: wildlife; wild animal; antimicrobial resistance; transmission; spread; One Health

Advanced Antimicrobial and Bioactive Coatings for Broad-Spectrum Protection

edited by

José Roberto Souza Almeida Leite

and

Andreanne Gomes Vasconcelos

submission deadline 31 Dec 2025 | Viewed by 125 | Submission Open

Keywords: antimicrobial coatings; bioactive surfaces; smart coatings for health; broad-spectrum antimicrobial materials; nanotechnology in antimicrobial coatings; disinfectant-compatible coatings; surface functionalization for microbial control; sustainable antimicrobial strategies

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Bacterial Extracellular Vesicles: Vehicles for Pathogenesis and Antibiotic Resistance

edited by

Eva Sapi

submission deadline 31 Dec 2025 | Viewed by 115 | Submission Open

Keywords: bacterial extracellular vesicles (BEVs); outer membrane vesicles (OMVs); antibiotic resistance; pathogenesis; host-pathogen interaction

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Advances in Antimicrobial Compounds: Exploring Natural, Synthetic, and Repositioned Drugs

edited by

Alessia Carocci

and Alexia Barbarossa

submission deadline 31 Dec 2025 | Viewed by 102 | Submission Open

Keywords: antimicrobial compounds; natural products; synthetic agents; drug repositioning; antimicrobial resistance; synergistic approaches; mechanisms of action; drug development

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Phage Therapy and Antimicrobial Innovation

edited by Ronen Hazan and

Lilach Gavish

submission deadline 31 Dec 2025 | Viewed by 101 | Submission Open

Keywords: antimicrobial resistance (AMR); antimicrobial innovation; phage therapy; phage engineering; synergistic strategies; chronic infections; biofilm; clinical phage microbiology; personalized medicine

(This special issue belongs to the Section Bacteriophages)

The One Health Perspective: Unveiling Animal and Zoonotic Microbiota in the Frame of Antimicrobial Resistance

edited by

Athina S. Tzora

and

Chrysoula Voidarou

submission deadline 31 Dec 2025 | Viewed by 99 | Submission Open

Keywords: antimicrobial resistance (AMR); One Health approach; veterinary medicine; livestock production; foodborne pathogen reservoirs; epidemiological mapping; resistance mechanisms; microbiome; resistome; intervention

(This special issue belongs to the Section Antibiotics in Animal Health)

Gram-Negative Multidrug-Resistant Pathogens and Their Treatment, 2nd Edition

edited by

Ramón Pérez-Tanoira

submission deadline 31 Dec 2025 | Viewed by 97 | Submission Open

Keywords: carbapenemase-producing enterobacteriaceae; multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa; gram-negative bacteria and antibiotic resistance mechanisms; multidrug resistant; extended-spectrum beta-lactamase (ESBL) producers; antibacterial potential of novel compounds; biofilm inhibition strategies; quorum sensing disruption as a therapeutic approach

Gram-Negative Infections in Humans and Companion Animals: A Global Threat

edited by

Gabriele Meroni

submission deadline 31 Dec 2025 | Viewed by 95 | Submission Open

Keywords: antimicrobial resistance; Gram-negative infections; humans; companion animals; essential oils; nanoparticles; pro-biotics; antimicrobial peptides; genomics; metagenomics

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Displaying special issue 251-300 on page 6 of 8.

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