Molecular Epidemiology and Antibiotic Resistance in MRSA: Recent Advances in Surveillance and Control

Dear Colleagues,

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the leading causes of healthcare-associated MRSA (HA-MRSA) infections, and its prevalence is increasing in community-associated MRSA (CA-MRSA) infections. MRSA is responsible for a variety of infections, ranging from simple skin and soft tissue infections to life-threatening bacteremia, pneumonia, and sepsis. Also of concern is the fact that MRSA exhibits resistance to nearly all β-lactams as well as to other antibiotic classes. This has serious implications for the treatment of severe infections with the potential to cause substantial mortality. Genomic analysis has revealed the distinct genetic origins, antimicrobial resistance determinants, and mobile genetic elements of several different MRSA clones and has also been used to monitor the spread of MRSA in healthcare and community settings. Hence, successful tracking of antibiotic resistance profiles at the molecular level and knowledge of MRSA prevalence are important to direct treatment therapies.

This Special Issue aims to present up-to-date research on the molecular epidemiology and antibiotic resistance of MRSA clinical isolates. Original research articles or reviews addressing the molecular epidemiology, evolution, and spread of MRSA, as well as surveillance and antibiotic resistance in MRSA are welcome.

Dr. Jae-Seok Kim
Guest Editor

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