Antimicrobial Prescribing, Population Use and Resistance, Impact in Global Health, 3rd Edition

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotics Use and Antimicrobial Stewardship".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 652

Special Issue Editors


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Guest Editor
Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain
Interests: interventions in public health; active aging; care in chronic diseases; food and nutrition; antibiotics and bacterial resistance; community nursing; health research; epidemiology
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain
Interests: clinic epidemiology; public health; methodology; biostatistics; bioethics
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Departament of Psychiatry, Radiology, Public Health, Nursing and Medicine, University of Santiago de Compostela, 15702 Santiago de Compostela, Spain
Interests: pharmacology; public health; vaccines; methodology; ecological studies
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We have published two successful editions of the Special Issue “Antimicrobial Prescribing, Population Use and Resistance and Impact in Global Health", and this encouraged us to launch a third edition focused on the same topic.

As a continuation of the previous Special Issues, this third edition will continue to address various public health strategies and interventions, as well as the application of innovations in managing antibiotics at the hospital level, to reduce the rate of antimicrobial resistance in the future. This Special Issue welcomes original research papers, reviews, qualitative research, and perspectives.

Potential topics for this Special Issue include, but are not limited to, the following:

  1. Novel methods for promoting appropriate antibiotic utilization;
  2. Influence of antimicrobial utilization changes on antimicrobial resistance;
  3. Antimicrobial utilization in special populations (e.g., pediatrics, geriatrics, emergency medicine, chronic diseases at the primary care level, etc.);
  4. Knowledge, attitudes and practice regarding antibiotic utilization and antimicrobial resistance in public and/or healthcare workers;
  5. New strategies to reduce antimicrobial resistances in hospitalized patients;
  6. New approaches to public health interventions for improving antibiotic utilization;
  7. Risk-stratified approaches for treating common infections in hospitalized patients.

Dr. Juan Manuel Vázquez-Lago
Dr. Ana Estany-Gestal
Dr. Angel Salgado-Barreira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • epidemiology
  • social behavior
  • antibiotic resistance
  • social factors
  • attitudes
  • knowledge
  • practice
  • qualitative research
  • public health interventions
  • antibiotic prescription
  • community care

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Published Papers (1 paper)

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Research

15 pages, 633 KiB  
Article
Performance of Early Sepsis Screening Tools for Timely Diagnosis and Antibiotic Stewardship in a Resource-Limited Thai Community Hospital
by Wisanu Wanlumkhao, Duangduan Rattanamongkolgul and Chatchai Ekpanyaskul
Antibiotics 2025, 14(7), 708; https://doi.org/10.3390/antibiotics14070708 - 15 Jul 2025
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Abstract
Background: Early identification of sepsis is critical for improving outcomes, particularly in low-resource emergency settings. In Thai community hospitals, where physicians may not always be available, triage is often nurse-led. Selecting accurate and practical sepsis screening tools is essential not only for timely [...] Read more.
Background: Early identification of sepsis is critical for improving outcomes, particularly in low-resource emergency settings. In Thai community hospitals, where physicians may not always be available, triage is often nurse-led. Selecting accurate and practical sepsis screening tools is essential not only for timely clinical decision-making but also for timely diagnosis and promoting appropriate antibiotic use. Methods: This cross-sectional study analyzed 475 adult patients with suspected sepsis who presented to the emergency department of a Thai community hospital, using retrospective data from January 2021 to December 2022. Six screening tools were evaluated: Systemic Inflammatory Response Syndrome (SIRS), Quick Sequential Organ Failure Assessment (qSOFA), Modified Early Warning Score (MEWS), National Early Warning Score (NEWS), National Early Warning Score version 2 (NEWS2), and Search Out Severity (SOS). Diagnostic accuracy was assessed using International Classification of Diseases, Tenth Revision (ICD-10) codes as the reference standard. Performance metrics included sensitivity, specificity, predictive values, likelihood ratios, and the area under the receiver operating characteristic (AUROC) curve, all reported with 95% confidence intervals. Results: SIRS had the highest sensitivity (84%), while qSOFA demonstrated the highest specificity (91%). NEWS2, NEWS, and MEWS showed moderate and balanced diagnostic accuracy. SOS also demonstrated moderate accuracy. Conclusions: A two-step screening approach—using SIRS for initial triage followed by NEWS2 for confirmation—is recommended. This strategy enhances nurse-led screening and optimizes limited resources in emergency care. Early sepsis detection through accurate screening tools constitutes a feasible public health intervention to support appropriate antibiotic use and mitigate antimicrobial resistance, especially in resource-limited community hospital settings. Full article
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