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Antibiotics
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Antimicrobial Prescribing, Population Use and Resistance, Impact in Global Health,...
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Antimicrobial Prescribing, Population Use and Resistance, Impact in Global Health, 3rd Edition

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotics Use and Antimicrobial Stewardship".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 5814

Special Issue Editors

Dr. Juan Manuel Vázquez-Lago

E-Mail Website
Guest Editor
Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain
Interests: interventions in public health; active aging; care in chronic diseases; food and nutrition; antibiotics and bacterial resistance; community nursing; health research; epidemiology
Special Issues, Collections and Topics in MDPI journals
Dr. Ana Estany-Gestal

E-Mail Website
Guest Editor
Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain
Interests: clinic epidemiology; public health; methodology; biostatistics; bioethics
Special Issues, Collections and Topics in MDPI journals
Dr. Angel Salgado-Barreira

E-Mail Website
Guest Editor
Departament of Psychiatry, Radiology, Public Health, Nursing and Medicine, University of Santiago de Compostela, 15702 Santiago de Compostela, Spain
Interests: pharmacology; public health; vaccines; methodology; ecological studies
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We have published two successful editions of the Special Issue “Antimicrobial Prescribing, Population Use and Resistance and Impact in Global Health", and this encouraged us to launch a third edition focused on the same topic.

As a continuation of the previous Special Issues, this third edition will continue to address various public health strategies and interventions, as well as the application of innovations in managing antibiotics at the hospital level, to reduce the rate of antimicrobial resistance in the future. This Special Issue welcomes original research papers, reviews, qualitative research, and perspectives.

Potential topics for this Special Issue include, but are not limited to, the following:

  1. Novel methods for promoting appropriate antibiotic utilization;
  2. Influence of antimicrobial utilization changes on antimicrobial resistance;
  3. Antimicrobial utilization in special populations (e.g., pediatrics, geriatrics, emergency medicine, chronic diseases at the primary care level, etc.);
  4. Knowledge, attitudes and practice regarding antibiotic utilization and antimicrobial resistance in public and/or healthcare workers;
  5. New strategies to reduce antimicrobial resistances in hospitalized patients;
  6. New approaches to public health interventions for improving antibiotic utilization;
  7. Risk-stratified approaches for treating common infections in hospitalized patients.

Dr. Juan Manuel Vázquez-Lago
Dr. Ana Estany-Gestal
Dr. Angel Salgado-Barreira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • epidemiology
  • social behavior
  • antibiotic resistance
  • social factors
  • attitudes
  • knowledge
  • practice
  • qualitative research
  • public health interventions
  • antibiotic prescription
  • community care

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  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Related Special Issue

Published Papers (2 papers)

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Research

11 pages, 626 KB  
Article
Knowledge and Confidence of Physician Assistant Students in Managing Patients with a Documented Penicillin Allergy
by Kayla Moody, David Weil, Sarah Jane O’Neal, Nicole Sunshine and P. Brandon Bookstaver
Antibiotics 2026, 15(1), 94; https://doi.org/10.3390/antibiotics15010094 - 16 Jan 2026
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Abstract
Objective: Physician assistants (PAs) are frequently involved in managing acute bacterial infections in patients with documented penicillin (PCN) allergies. Inappropriate antibiotic choice in patients with existing allergies may place them at undue risk. This study aimed to assess the knowledge and confidence among [...] Read more.
Objective: Physician assistants (PAs) are frequently involved in managing acute bacterial infections in patients with documented penicillin (PCN) allergies. Inappropriate antibiotic choice in patients with existing allergies may place them at undue risk. This study aimed to assess the knowledge and confidence among PA students in managing patients with documented PCN allergies. Methods: An electronic survey was distributed to enrolled students in participating PA programs in North and South Carolina. The survey tool consisted of 20 questions with 13 focused on knowledge and confidence primarily scored on a 5-point Likert scale. Data were collected and protected via the REDCap® database. Primary objectives were knowledge of penicillin allergies and confidence in management decisions. Sufficient knowledge was considered a score of 80% or greater; adequate knowledge was considered 70% or greater on relevant assessments. Results: Overall, 406 students from 10 unique programs completed the survey. They were predominantly female (76%) with 43% in the first year of their program. The mean student knowledge score was 25.9%, and 30% of respondents achieved adequate knowledge. Respondents reported an average cross reactivity between penicillin and beta-lactams of 29% (10–63%), cefazolin 50% (24–75), ceftriaxone 29% (11–60), and carbapenems 26% (8–50). The majority of respondents (66.5%) reported high levels of confidence in managing patients with penicillin allergies. Conclusions: The study found significant discordance between PA students’ high level of confidence in assessing patients with a PCN allergy and their comparative knowledge. PA students are likely to avoid beta-lactam antibiotics when there is a documented penicillin allergy, regardless of the documented reaction or low likelihood of cross-reactivity. Further training and education will help to encourage appropriate prescribing in these high-risk patients. Full article
(This article belongs to the Special Issue Antimicrobial Prescribing, Population Use and Resistance, Impact in Global Health, 3rd Edition)
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15 pages, 633 KB  
Article
Performance of Early Sepsis Screening Tools for Timely Diagnosis and Antibiotic Stewardship in a Resource-Limited Thai Community Hospital
by Wisanu Wanlumkhao, Duangduan Rattanamongkolgul and Chatchai Ekpanyaskul
Antibiotics 2025, 14(7), 708; https://doi.org/10.3390/antibiotics14070708 - 15 Jul 2025
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Abstract
Background: Early identification of sepsis is critical for improving outcomes, particularly in low-resource emergency settings. In Thai community hospitals, where physicians may not always be available, triage is often nurse-led. Selecting accurate and practical sepsis screening tools is essential not only for timely [...] Read more.
Background: Early identification of sepsis is critical for improving outcomes, particularly in low-resource emergency settings. In Thai community hospitals, where physicians may not always be available, triage is often nurse-led. Selecting accurate and practical sepsis screening tools is essential not only for timely clinical decision-making but also for timely diagnosis and promoting appropriate antibiotic use. Methods: This cross-sectional study analyzed 475 adult patients with suspected sepsis who presented to the emergency department of a Thai community hospital, using retrospective data from January 2021 to December 2022. Six screening tools were evaluated: Systemic Inflammatory Response Syndrome (SIRS), Quick Sequential Organ Failure Assessment (qSOFA), Modified Early Warning Score (MEWS), National Early Warning Score (NEWS), National Early Warning Score version 2 (NEWS2), and Search Out Severity (SOS). Diagnostic accuracy was assessed using International Classification of Diseases, Tenth Revision (ICD-10) codes as the reference standard. Performance metrics included sensitivity, specificity, predictive values, likelihood ratios, and the area under the receiver operating characteristic (AUROC) curve, all reported with 95% confidence intervals. Results: SIRS had the highest sensitivity (84%), while qSOFA demonstrated the highest specificity (91%). NEWS2, NEWS, and MEWS showed moderate and balanced diagnostic accuracy. SOS also demonstrated moderate accuracy. Conclusions: A two-step screening approach—using SIRS for initial triage followed by NEWS2 for confirmation—is recommended. This strategy enhances nurse-led screening and optimizes limited resources in emergency care. Early sepsis detection through accurate screening tools constitutes a feasible public health intervention to support appropriate antibiotic use and mitigate antimicrobial resistance, especially in resource-limited community hospital settings. Full article
(This article belongs to the Special Issue Antimicrobial Prescribing, Population Use and Resistance, Impact in Global Health, 3rd Edition)
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