Diagnostics, Antibiotic Usage and Surgery Related Techniques in Prevention and Treatment of Prosthetic Joint and Implant Related Infections
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotic Therapy in Infectious Diseases".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 21
Special Issue Editors
Interests: primary and revision joint arthroplasty of hip and knee; diagnostics and therapy of bone and joint infections
Special Issues, Collections and Topics in MDPI journals
Interests: the care of severe injuries; orthopedics and trauma surgery; special trauma surgery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Prosthetic joint infections (PJIs) remain among the most serious and complex complications that can follow joint arthroplasty, particularly in hip and knee replacements. With the global increase in both primary and revision joint arthroplasty procedures, the incidence and clinical burden of PJIs are growing. These infections not only compromise patient outcomes but also pose substantial challenges to orthopedic surgeons and infectious disease specialists alike.
The accurate and timely diagnosis of PJIs is crucial. Advances in imaging, molecular diagnostics, and biomarker identification are improving our ability to detect infections early and implement targeted therapy. Still, there remains a need for standardized diagnostic criteria and personalized treatment strategies, especially in the setting of multidrug-resistant organisms and recurrent infections.
Antibiotic usage plays a pivotal role throughout the continuum of care—from prophylaxis during primary arthroplasty to salvage procedures in complex revision cases. While perioperative antibiotic prophylaxis has significantly reduced infection rates in primary procedures, managing infections in revision arthroplasty is markedly more complicated due to factors such as antibiotic resistance and the formation of biofilms on implants.
Equally critical are surgical techniques for preventing and treating PJI and FRI. Skin preparation, irrigation solutions, and debridement techniques are some examples of these.
This Special Issue focuses on antibiotic strategies in primary and revision joint arthroplasty and the evolving landscape of diagnostics and therapies for bone and joint infections. Original articles and meta-analyses in both clinical and basic research are welcome, as well as review articles that summarize the newest knowledge in the field.
Prof. Dr. Bernd Fink
Prof. Dr. Steffen Ruchholtz
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- periprosthetic joint infection
- implant-related infection
- antibiotics
- spacer
- diagnosis
- septic revision arthroplasty
- irrigation
- debridement
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