Antimicrobial Activity of Medical Materials, 2nd Edition

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antimicrobial Materials and Surfaces".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 635

Special Issue Editors


E-Mail Website
Guest Editor
Universidade do Minho, Braga, Portugal
Interests: microbial biofilms; biofilm prevention; alternative therapies; antimicrobial materials

E-Mail Website
Guest Editor
Universidade do Minho, Braga, Portugal
Interests: microbial biofilms; biofilm prevention; alternative therapies; antimicrobial materials

Special Issue Information

Dear Colleagues,

The first edition of this Special Issue, entitled “Antimicrobial Activity of Medical Materials”, was published in 2022. It is a collection with seven excellent papers, and its success has encouraged us to open a second edition with the same topic.

As a continuation of the first Special Issue, this second edition aims to publish review and research papers touching on any antimicrobial medical devices/surfaces, as well as on the various methods and preclinical and clinical trials developed to assess their efficiency.

Dr. Tânia Grainha
Dr. Susana Lopes
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial surfaces
  • copper
  • silver
  • surface functionalization/modifications
  • biofilm prevention
  • medical textiles
  • efficiency

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Published Papers (1 paper)

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Research

16 pages, 23452 KB  
Article
Effects of Different Zinc Modulations in Glass Ionomer Cements on Multi-Species Biofilm Formation and Human Tooth Demineralization: An In Vitro Study
by İpek Ören Bozyer, Khairul Matin, Tijen Pamir, Sema Belli and Yasushi Shimada
Antibiotics 2026, 15(5), 489; https://doi.org/10.3390/antibiotics15050489 - 12 May 2026
Viewed by 238
Abstract
Background: Biofilm formation and associated tooth demineralization are key factors influencing the clinical performance of dental materials. Methods: This study compared the antibiofilm and demineralization preventive effects of two zinc-modified glass ionomer cements (Zn-GICs) with a conventional GIC. Disk-shaped specimens of Caredyne Restore [...] Read more.
Background: Biofilm formation and associated tooth demineralization are key factors influencing the clinical performance of dental materials. Methods: This study compared the antibiofilm and demineralization preventive effects of two zinc-modified glass ionomer cements (Zn-GICs) with a conventional GIC. Disk-shaped specimens of Caredyne Restore (CR), ChemFil Rock (CFR), and Ketac Molar (KM) (n = 6) were evaluated in a multi-species biofilm model using an oral biofilm reactor. Early biofilm formation was analyzed by scanning electron microscopy (after 2 h and 4 h), bacterial accumulation and water-insoluble glucan (WIG) production were quantified (after 12 h). For demineralization assessment, restored human enamel and dentin specimens (n = 6) including an additional resin-based control group (Dura Seal, DS) were subjected to a 14-day biofilm challenge and lesion depth was measured using swept-source optical coherence tomography and confocal microscopy. Results: CR showed significantly lower bacterial accumulation and WIG production than the other materials (p < 0.05). CFR demonstrated lower bacterial levels than KM (p < 0.05), whereas no significant differences were observed between CFR and KM in WIG production (p > 0.05). CR produced the shallowest enamel and dentin lesions, whereas DS exhibited the deepest (p < 0.05); however, no statistically significant differences were observed between CFR and KM in lesion depth (p > 0.05). Conclusions: CR demonstrated superior biofilm suppression and reduced demineralization, whereas CFR showed limited differences compared with the conventional GIC. Full article
(This article belongs to the Special Issue Antimicrobial Activity of Medical Materials, 2nd Edition)
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