The Antimicrobial Activity of Metal-Based Nanoparticles

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antimicrobial Materials and Surfaces".

Deadline for manuscript submissions: 15 October 2025 | Viewed by 1042

Special Issue Editor


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Guest Editor
Multidisciplinary Laboratory on Health and Environment, Federal University of São Paulo, Diadema, Brazil
Interests: antibiotic resistance; metal-based nanoparticles; biocides; antisseptics; bioactives; biopolymers; bioeconomy

Special Issue Information

Dear Colleagues,

Metal-based nanoparticles have been widely used for their versatility for multiple purposes, including environmental, clinical, urban and industrial applications. They can be prepared from many metal sources, as well as via various routes, including chemical, physical–chemical and biogenic synthesis. To identify efficient alternative materials, including nanomaterials and composites, this Special Issue will give specific attention to biocides, antiseptics, pesticides and/or inhibitors preventing microbial growth by using any well-known or completely new mechanisms to promote the deactivation of microbial replication.  Submissions describing metal-based nanoparticles, with effective antiseptic, disinfectant, biocide, or pesticide actions that can be used to reduce the transmission and propagation of microorganisms in different contexts and environments, are especially encouraged.

Dr. Suzan Pantaroto de Vasconcellos
Guest Editor

Manuscript Submission Information

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Keywords

  • metal-nanoparticle
  • microbicide
  • virucide
  • phytopathogens
  • disinfectant
  • synthesis
  • antibiotic resistance

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Published Papers (1 paper)

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Research

9 pages, 924 KiB  
Article
Does the Silver Nanoparticles Production Route Affect the Proliferation of Antibiotic Resistance in Soil Ecosystem?
by Jana Sedlakova-Kadukova, Miroslava Sincak and Veronika Demčakova
Antibiotics 2025, 14(1), 15; https://doi.org/10.3390/antibiotics14010015 - 29 Dec 2024
Viewed by 860
Abstract
Introduction: Silver nanoparticles (AgNPs) are widely utilized for their exceptional antimicrobial properties, but concerns persist regarding their environmental impacts, particularly in soil and water ecosystems. This study compared the effects of chemically and biologically synthesized AgNPs and ionic silver on bacterial communities commonly [...] Read more.
Introduction: Silver nanoparticles (AgNPs) are widely utilized for their exceptional antimicrobial properties, but concerns persist regarding their environmental impacts, particularly in soil and water ecosystems. This study compared the effects of chemically and biologically synthesized AgNPs and ionic silver on bacterial communities commonly present in soil and the proliferation of antibiotic resistance in the soil ecosystem. Results and Discussion: Biologically synthesized AgNPs exhibited the strongest antimicrobial activity, significantly reducing bacterial populations within a day, and demonstrated minimal impacts on the development of antibiotic resistance in long-term. Notably, resistance to ampicillin was lower by 72% in comparison with a control after 90 days in the presence of biologically produced AgNPs, while resistance to tetracycline and kanamycin dropped to nearly negligible levels. In contrast, chemically synthesized AgNPs and ionic silver substantially increased antibiotic resistance in long-term, particularly to ampicillin and chloramphenicol, where resistance levels were 11 to 13 times higher than the controls, respectively. Chemically synthesized AgNPs caused a gradual rise in resistance, while ionic silver induced consistently elevated resistance throughout the study. Conclusions: These differences highlight the complex interplay between nanoparticle composition and bacterial adaptation. The findings suggest that biologically synthesized AgNPs are a promising environmentally friendly alternative, reducing bacterial resistance and mitigating the risks associated with silver-induced antibiotic resistance in soil ecosystems. They have greater potential for sustainable applications while addressing critical concerns about antimicrobial resistance and environmental safety. Full article
(This article belongs to the Special Issue The Antimicrobial Activity of Metal-Based Nanoparticles)
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