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Tomography, Volume 8, Issue 3

2022 June - 40 articles

Cover Story: Coronary optical coherence tomography (OCT) is a light-based, intravascular imaging modality that can visualise plaque components in high resolution. This resolution is critical when identifying vulnerable plaque features, such as thin cap fibroatheroma, which dramatically increase the risk of future major adverse cardiac events (MACE). However, extracting these features is often carried out manually, a tedious and time-consuming process that limits its clinical utility. Computational techniques are emerging to automate this process, enabling near-real time image analyses and subsequent three-dimensional simulation to assist in identifying patients most at risk of future MACE. Here, we discuss recent advances in these techniques and their ability to identify the coronary lumen, artery layers, plaque components, and subtypes and stents. View this paper
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Articles (40)

  • Article
  • Open Access
7 Citations
2,951 Views
11 Pages

20 June 2022

Coronary artery anomalies (CAAs) are rare anatomical variations characterized by abnormal origin, course, or termination of the coronary arteries. This study aims to identify incidental CAAs in patients who underwent multidetector computed tomography...

  • Article
  • Open Access
1 Citations
2,492 Views
13 Pages

20 June 2022

This app project was aimed to remotely deliver diagnoses and disease-progression information to COVID-19 patients to help minimize risk during this and future pandemics. Data collected from chest computed tomography (CT) scans of COVID-19-infected pa...

  • Article
  • Open Access
2 Citations
3,156 Views
10 Pages

Follow-Up Assessment of Intracranial Aneurysms Treated with Endovascular Coiling: Comparison of Compressed Sensing and Parallel Imaging Time-of-Flight Magnetic Resonance Angiography

  • Gianfranco Vornetti,
  • Fiorina Bartiromo,
  • Francesco Toni,
  • Massimo Dall’Olio,
  • Mario Cirillo,
  • Peter Speier,
  • Ciro Princiotta,
  • Michaela Schmidt,
  • Caterina Tonon and
  • Luigi Cirillo
  • + 2 authors

18 June 2022

The aim of our study was to compare compressed sensing (CS) time-of-flight (TOF) magnetic resonance angiography (MRA) with parallel imaging (PI) TOF MRA in the evaluation of patients with intracranial aneurysms treated with coil embolization or stent...

  • Article
  • Open Access
2,889 Views
13 Pages

Reclassification of Heart Failure with Preserved Ejection Fraction Following Cardiac Sympathetic Nervous System Activation: A New Cutoff Value of 58%

  • Toshihiko Goto,
  • Takafumi Nakayama,
  • Junki Yamamoto,
  • Kento Mori,
  • Yasuhiro Shintani,
  • Shohei Kikuchi,
  • Hiroshi Fujita,
  • Hidekatsu Fukuta and
  • Yoshihiro Seo

18 June 2022

Heart failure (HF) with preserved left ventricular ejection fraction (LVEF) is a heterogeneous syndrome. An LVEF of 50% is widely used to categorize patients with HF; however, this is controversial. Previously, we have reported that patients with an...

  • Article
  • Open Access
2 Citations
2,519 Views
9 Pages

Clinical Routine and Necessary Advances in Soft Tissue Tumor Imaging Based on the ESSR Guideline: Initial Findings

  • Alexander Korthaus,
  • Sebastian Weiss,
  • Alexej Barg,
  • Johannes Salamon,
  • Carsten Schlickewei,
  • Karl-Heinz Frosch and
  • Matthias Priemel

17 June 2022

Soft tissue sarcomas are malignant diseases with a complex classification and various histological subtypes, mostly clinically inconspicuous appearance, and a rare occurrence. To ensure safe patient care, the European Society of Musculoskeletal Radio...

  • Article
  • Open Access
1 Citations
2,798 Views
8 Pages

Quantitative Chest CT Analysis to Measure Short-Term Sequelae of COVID-19 Pneumonia: A Monocentric Prospective Study

  • Ezio Lanza,
  • Angela Ammirabile,
  • Maddalena Casana,
  • Daria Pocaterra,
  • Federica Maria Pilar Tordato,
  • Benedetta Varisco,
  • Costanza Lisi,
  • Gaia Messana,
  • Luca Balzarini and
  • Paola Morelli

17 June 2022

(1) Background: Quantitative CT analysis (QCT) has demonstrated promising results in the prognosis prediction of patients affected by COVID-19. We implemented QCT not only at diagnosis but also at short-term follow-up, pairing it with a clinical exam...

  • Case Report
  • Open Access
8 Citations
3,041 Views
8 Pages

Imaging Neurodegenerative Metabolism in Amyotrophic Lateral Sclerosis with Hyperpolarized [1-13C]pyruvate MRI

  • Nikolaj Bøgh,
  • Christoffer Laustsen,
  • Esben S. S. Hansen,
  • Hatice Tankisi,
  • Lotte B. Bertelsen and
  • Jakob U. Blicher

14 June 2022

The cause of amyotrophic lateral sclerosis (ALS) is still unknown, and consequently, early diagnosis of the disease can be difficult and effective treatment is lacking. The pathology of ALS seems to involve specific disturbances in carbohydrate metab...

  • Article
  • Open Access
5 Citations
2,440 Views
18 Pages

The Influence of Data-Driven Compressed Sensing Reconstruction on Quantitative Pharmacokinetic Analysis in Breast DCE MRI

  • Ping Ni Wang,
  • Julia V. Velikina,
  • Leah C. Henze Bancroft,
  • Alexey A. Samsonov,
  • Frederick Kelcz,
  • Roberta M. Strigel and
  • James H. Holmes

14 June 2022

Radial acquisition with MOCCO reconstruction has been previously proposed for high spatial and temporal resolution breast DCE imaging. In this work, we characterize MOCCO across a wide range of temporal contrast enhancement in a digital reference obj...

  • Article
  • Open Access
26 Citations
3,865 Views
8 Pages

Magnetic Susceptibility Source Separation Solely from Gradient Echo Data: Histological Validation

  • Alexey V. Dimov,
  • Kelly M. Gillen,
  • Thanh D. Nguyen,
  • Jerry Kang,
  • Ria Sharma,
  • David Pitt,
  • Susan A. Gauthier and
  • Yi Wang

14 June 2022

Quantitative susceptibility mapping (QSM) facilitates mapping of the bulk magnetic susceptibility of tissue from the phase of complex gradient echo (GRE) MRI data. QSM phase processing combined with an R2* model of magnitude of multiecho gradient ech...

  • Article
  • Open Access
3,056 Views
10 Pages

Alert Germ Infections: Chest X-ray and CT Findings in Hospitalized Patients Affected by Multidrug-Resistant Acinetobacter baumannii Pneumonia

  • Raffaella Capasso,
  • Antonio Pinto,
  • Nicola Serra,
  • Umberto Atripaldi,
  • Adele Corcione,
  • Giorgio Bocchini,
  • Salvatore Guarino,
  • Roberta Lieto,
  • Gaetano Rea and
  • Tullio Valente
  • + 1 author

14 June 2022

Acinetobacter baumannii (Ab) is an opportunistic Gram-negative pathogen intrinsically resistant to many antimicrobials. The aim of this retrospective study was to describe the imaging features on chest X-ray (CXR) and computed tomography (CT) scans i...

  • Article
  • Open Access
9 Citations
4,984 Views
12 Pages

Visual Evaluation of Ultrafast MRI in the Assessment of Residual Breast Cancer After Neoadjuvant Systemic Therapy: A Preliminary Study Association with Subtype

  • Maya Honda,
  • Masako Kataoka,
  • Mami Iima,
  • Rie Ota,
  • Akane Ohashi,
  • Ayami Ohno Kishimoto,
  • Kanae Kawai Miyake,
  • Marcel Dominik Nickel,
  • Yosuke Yamada and
  • Yuji Nakamoto
  • + 1 author

10 June 2022

The purpose of this study was to investigate the diagnostic performance of ultrafast DCE (UF-DCE) MRI after the completion of neoadjuvant systemic therapy (NST) in breast cancer. In this study, MR examinations of 55 post-NST breast cancers were retro...

  • Article
  • Open Access
2 Citations
3,304 Views
13 Pages

Dynamic Contrast Enhanced Study in Multiparametric Examination of the Prostate—Can We Make Better Use of It?

  • Silva Guljaš,
  • Mirta Benšić,
  • Zdravka Krivdić Dupan,
  • Oliver Pavlović,
  • Vinko Krajina,
  • Deni Pavoković,
  • Petra Šmit Takač,
  • Matija Hranić and
  • Tamer Salha

9 June 2022

We sought to investigate whether quantitative parameters from a dynamic contrast-enhanced study can be used to differentiate cancer from normal tissue and to determine a cut-off value of specific parameters that can predict malignancy more accurately...

  • Case Report
  • Open Access
1 Citations
2,698 Views
6 Pages

Atypical Cognitive Impairment and Recovery in Two Colorectal Cancer Patients

  • Hui Su Lee,
  • Hwan Ho Jo,
  • Ko Woon Kim,
  • Byoung-Soo Shin and
  • Hyun Goo Kang

9 June 2022

Cognitive impairment in cancer patients can be caused by various factors; in approximately 30% of cancer patients, the symptoms appear before starting treatment. Paraneoplastic limbic encephalitis (PLE) is a rare disease associated with an autoimmune...

  • Article
  • Open Access
4 Citations
3,231 Views
10 Pages

9 June 2022

Purpose: The purpose of this study was to investigate which findings were delayed in diagnosis with respect to chest CT findings of paragonimiasis. Methods: This retrospective, informed questionnaire study was conducted to evaluate chest CT scans of...

  • Article
  • Open Access
2 Citations
3,251 Views
8 Pages

Changes of Brain Structures and Psychological Characteristics in Predatory, Affective Violent and Nonviolent Offenders

  • Ming-Chung Chou,
  • Tien-Cheng Cheng,
  • Pinchen Yang,
  • Rueih-Chin Lin and
  • Ming-Ting Wu

8 June 2022

Purpose: Violent subjects were demonstrated to exhibit abnormal brain structures; however, the brain changes may be different between criminals committing affective (VA), predatory violence (VP), and non-violence (NV). Therefore, the purpose of this...

  • Article
  • Open Access
1 Citations
4,265 Views
8 Pages

3 June 2022

Background: 18F-fluciclovine is a positron emission tomography (PET) radiotracer approved for the detection of prostate cancer recurrence. No effect of androgen deprivation therapy (ADT) on its performance has been established. Purpose: To study the...

  • Article
  • Open Access
40 Citations
4,906 Views
11 Pages

Image Quality and Radiation Dose of Contrast-Enhanced Chest-CT Acquired on a Clinical Photon-Counting Detector CT vs. Second-Generation Dual-Source CT in an Oncologic Cohort: Preliminary Results

  • Florian Hagen,
  • Lukas Walder,
  • Jan Fritz,
  • Ralf Gutjahr,
  • Bernhard Schmidt,
  • Sebastian Faby,
  • Fabian Bamberg,
  • Stefan Schoenberg,
  • Konstantin Nikolaou and
  • Marius Horger

3 June 2022

Our aim was to compare the image quality and patient dose of contrast-enhanced oncologic chest-CT of a first-generation photon-counting detector (PCD-CT) and a second-generation dual-source dual-energy CT (DSCT). For this reason, one hundred consecut...

  • Article
  • Open Access
6 Citations
5,602 Views
10 Pages

Web-Based Application for Biomedical Image Registry, Analysis, and Translation (BiRAT)

  • Rahul Pemmaraju,
  • Robert Minahan,
  • Elise Wang,
  • Kornel Schadl,
  • Heike Daldrup-Link and
  • Frezghi Habte

30 May 2022

Imaging has become an invaluable tool in preclinical research for its capability to non-invasively detect and monitor disease and assess treatment response. With the increased use of preclinical imaging, large volumes of image data are being generate...

  • Article
  • Open Access
2 Citations
2,890 Views
16 Pages

Characterization of Cognitive Function in Survivors of Diffuse Gliomas Using Morphometric Correlation Networks

  • Chencai Wang,
  • Nicholas S. Cho,
  • Kathleen Van Dyk,
  • Sabah Islam,
  • Catalina Raymond,
  • Justin Choi,
  • Noriko Salamon,
  • Whitney B. Pope,
  • Albert Lai and
  • Benjamin M. Ellingson
  • + 2 authors

26 May 2022

This pilot study investigates structural alterations and their relationships with cognitive function in survivors of diffuse gliomas. Twenty-four survivors of diffuse gliomas (mean age 44.5 ± 11.5), from whom high-resolution T1-weighted images...

  • Article
  • Open Access
12 Citations
7,152 Views
8 Pages

Temporal Horn Enlargements Predict Secondary Hydrocephalus Diagnosis Earlier than Evans’ Index

  • Paolo Missori,
  • Sergio Paolini,
  • Simone Peschillo,
  • Cristina Mancarella,
  • Anthony Kevin Scafa,
  • Emanuela Rastelli,
  • Stefano Martini,
  • Francesco Fattapposta and
  • Antonio Currà

25 May 2022

The aim of this study was to identify early radiological signs of secondary hydrocephalus. We retrieved neuroradiological data from scans performed at various times in patients who underwent surgery for secondary hydrocephalus due to severe traumatic...

  • Article
  • Open Access
5 Citations
2,451 Views
16 Pages

Imaging of Transmetallation and Chelation Phenomena Involving Radiological Contrast Agents in Mineral-Rich Fruits

  • Subhendra Sarkar,
  • Zoya Vinokur,
  • Bleidis Buitrago,
  • Lin Mousa,
  • Hayley Sanchez,
  • Analia Basilicata,
  • Jodi-Ann Douglas and
  • Seanetta Reddock

23 May 2022

Exogenous heavy metals or non-metallic waste products, for example lanthanide or iodinated contrast media for radiological procedures, may interfere with the biochemical pools in patients and in common food sources, creating an excess buildup of exog...

  • Article
  • Open Access
5 Citations
4,068 Views
12 Pages

Patient Comfort in Modern Computed Tomography: What Really Counts

  • Julius Henning Niehoff,
  • Andreas Heuser,
  • Arwed Elias Michael,
  • Simon Lennartz,
  • Jan Borggrefe and
  • Jan Robert Kroeger

23 May 2022

Background: The purpose of the present study is to evaluate the patient comfort during CT examinations with a modern CT scanner (Photon-Counting CT (PCCT)) and to compare the perceived patient comfort with a standard CT scanner. Methods: A total of 1...

  • Review
  • Open Access
9 Citations
5,245 Views
15 Pages

Role of CT and MRI in Cardiac Emergencies

  • Carlo Liguori,
  • Stefania Tamburrini,
  • Giovanni Ferrandino,
  • Silvio Leboffe,
  • Nicola Rosano and
  • Ines Marano

23 May 2022

Current strategies for the evaluation of patients with chest pain have significantly changed thanks to the implemented potentiality of CT and MRI. The possible fatal consequences and high malpractice costs of missed acute coronary syndromes lead to u...

  • Article
  • Open Access
1 Citations
3,535 Views
12 Pages

22 May 2022

This study aimed to select the pulse sequence providing the optimal MRCP image quality by applying various reduction and denoising level parameters—which could improve image quality and shorten examination time—to BH-2D-SSh TSE, RT- 2D-SE...

  • Article
  • Open Access
6 Citations
2,694 Views
11 Pages

Analysis of Spatial Heterogeneity of Responses in Metastatic Sites in Renal Cell Carcinoma Patients Treated with Nivolumab

  • Ankush Jajodia,
  • Varun Goel,
  • Nivedita Patnaik,
  • Sunil Pasricha,
  • Gurudutt Gupta,
  • Ullas Batra and
  • Vineet Talwar

20 May 2022

Background: The purpose was to determine whether tumor response to CPI varies by organ and to characterize response patterns in a group of surgically treated metastatic RCC patients treated with Nivolumab. Methods: A retrospective analysis was undert...

  • Article
  • Open Access
7 Citations
3,984 Views
13 Pages

Prognostic Accuracy of CTP Summary Maps in Patients with Large Vessel Occlusive Stroke and Poor Revascularization after Mechanical Thrombectomy—Comparison of Three Automated Perfusion Software Applications

  • Iris Muehlen,
  • Matthias Borutta,
  • Gabriela Siedler,
  • Tobias Engelhorn,
  • Stefan Hock,
  • Michael Knott,
  • Philip Hoelter,
  • Bastian Volbers,
  • Stefan Schwab and
  • Arnd Doerfler

17 May 2022

Background: Innovative automated perfusion software solutions offer support in the management of acute stroke by providing information about the infarct core and penumbra. While the performance of different software solutions has mainly been investig...

  • Review
  • Open Access
17 Citations
6,503 Views
43 Pages

Automated Coronary Optical Coherence Tomography Feature Extraction with Application to Three-Dimensional Reconstruction

  • Harry J. Carpenter,
  • Mergen H. Ghayesh,
  • Anthony C. Zander,
  • Jiawen Li,
  • Giuseppe Di Giovanni and
  • Peter J. Psaltis

17 May 2022

Coronary optical coherence tomography (OCT) is an intravascular, near-infrared light-based imaging modality capable of reaching axial resolutions of 10–20 µm. This resolution allows for accurate determination of high-risk plaque features,...

  • Article
  • Open Access
14 Citations
7,324 Views
14 Pages

11 May 2022

This study aims to determine the correlation between the mean value of bone density measured on the CBCT device and the primary stability of dental implants determined by resonant frequency analysis. An experimental study was conducted on a material...

  • Article
  • Open Access
9 Citations
3,056 Views
16 Pages

Chemical Exchange Saturation Transfer for Lactate-Weighted Imaging at 3 T MRI: Comprehensive In Silico, In Vitro, In Situ, and In Vivo Evaluations

  • Karl Ludger Radke,
  • Daniel B. Abrar,
  • Miriam Frenken,
  • Lena Marie Wilms,
  • Benedikt Kamp,
  • Matthias Boschheidgen,
  • Patrick Liebig,
  • Alexandra Ljimani,
  • Timm Joachim Filler and
  • Anja Müller-Lutz
  • + 3 authors

7 May 2022

Based on in silico, in vitro, in situ, and in vivo evaluations, this study aims to establish and optimize the chemical exchange saturation transfer (CEST) imaging of lactate (Lactate-CEST—LATEST). To this end, we optimized LATEST sequences usin...

  • Article
  • Open Access
7 Citations
3,274 Views
7 Pages

The Role of Transperineal Ultrasound for the Assessment of the Anorectal Angle and Its Relationship with Levator Ani Muscle Avulsion

  • José Antonio García-Mejido,
  • Sara García-Pombo,
  • Cristina Fernández-Conde,
  • Carlota Borrero,
  • Ana Fernández-Palacín and
  • José Antonio Sainz-Bueno

6 May 2022

The relationship between the anorectal angle (ARA) and the levator ani muscle (LAM) is well known. In this study, we aimed to demonstrate that the ARA changes when LAM avulsion occurs after vaginal delivery. This was a secondary, observational retros...

  • Article
  • Open Access
1 Citations
2,867 Views
10 Pages

5 May 2022

Background: To compare a model-based iterative reconstruction (MBIR) versus a hybrid iterative reconstruction (HIR) for initial and final Alberta Stroke Program Early Ct Score (ASPECT) scoring in acute ischemic stroke (AIS). We hypothesized that MBIR...

  • Article
  • Open Access
5 Citations
3,355 Views
16 Pages

Generation of Synthetic-Pseudo MR Images from Real CT Images

  • Isam F. Abu-Qasmieh,
  • Ihssan S. Masad,
  • Hiam H. Al-Quran and
  • Khaled Z. Alawneh

3 May 2022

This study aimed to generate synthetic MR images from real CT images. CT# mean and standard deviation of a moving window across every pixel in the reconstructed CT images were mapped to their corresponding tissue-mimicking types. Identification of th...

  • Article
  • Open Access
19 Citations
6,173 Views
13 Pages

Spontaneous Retroperitoneal Hematoma Treated with Percutaneous Transarterial Embolization in COVID-19 Era: Diagnostic Findings and Procedural Outcome

  • Francesco Tiralongo,
  • Salvatore Seminatore,
  • Stefano Di Pietro,
  • Giulio Distefano,
  • Federica Galioto,
  • Francesco Vacirca,
  • Francesco Giurazza,
  • Stefano Palmucci,
  • Massimo Venturini and
  • Antonio Basile
  • + 1 author

1 May 2022

(1) Background: Spontaneous retroperitoneal hematomas are a relatively common occurrence in hospitalized patients with COVID-19 related pneumonia, and endovascular treatment of trans-arterial embolization (TAE) may be a life-saving procedure after fa...

  • Article
  • Open Access
12 Citations
3,368 Views
7 Pages

Diagnostic Accuracy of Chest Digital Tomosynthesis in Patients Recovering after COVID-19 Pneumonia

  • Elisa Baratella,
  • Barbara Ruaro,
  • Cristina Marrocchio,
  • Gabriele Poillucci,
  • Caterina Pigato,
  • Alessandro Marco Bozzato,
  • Francesco Salton,
  • Paola Confalonieri,
  • Filippo Crimi and
  • Maria Assunta Cova
  • + 2 authors

24 April 2022

Purpose: To assess the diagnostic accuracy of traditional chest X-ray (CXR) and digital tomosynthesis (DTS) compared to computed tomography (CT) in detecting pulmonary interstitial changes in patients having recovered from severe COVID-19. Materials...

  • Article
  • Open Access
6 Citations
3,187 Views
13 Pages

Effect of Inter-Reader Variability on Diffusion-Weighted MRI Apparent Diffusion Coefficient Measurements and Prediction of Pathologic Complete Response for Breast Cancer

  • Nu N. Le,
  • Wen Li,
  • Natsuko Onishi,
  • David C. Newitt,
  • Jessica E. Gibbs,
  • Lisa J. Wilmes,
  • John Kornak,
  • Savannah C. Partridge,
  • Barbara LeStage and
  • Nola M. Hylton
  • + 3 authors

22 April 2022

This study evaluated the inter-reader agreement of tumor apparent diffusion coefficient (ADC) measurements performed on breast diffusion-weighted imaging (DWI) for assessing treatment response in a multi-center clinical trial of neoadjuvant chemother...

  • Article
  • Open Access
3 Citations
5,403 Views
12 Pages

Predictors of Metastatic Lymph Nodes at Preoperative Staging CT in Gastric Adenocarcinoma

  • Filippo Crimì,
  • Quoc Riccardo Bao,
  • Valentina Mari,
  • Chiara Zanon,
  • Giulio Cabrelle,
  • Gaya Spolverato,
  • Salvatore Pucciarelli and
  • Emilio Quaia

22 April 2022

Background. The aim of this study was to identify the most accurate computed-tomography (CT) dimensional criteria of loco-regional lymph nodes (LNs) for detecting nodal metastases in gastric cancer (GC) patients. Methods. Staging CTs of surgically re...

  • Article
  • Open Access
33 Citations
4,984 Views
12 Pages

Follow-Up CT Patterns of Residual Lung Abnormalities in Severe COVID-19 Pneumonia Survivors: A Multicenter Retrospective Study

  • Giulia Besutti,
  • Filippo Monelli,
  • Silvia Schirò,
  • Francesca Milone,
  • Marta Ottone,
  • Lucia Spaggiari,
  • Nicola Facciolongo,
  • Carlo Salvarani,
  • Stefania Croci and
  • Nicola Sverzellati
  • + 1 author

20 April 2022

Prior studies variably reported residual chest CT abnormalities after COVID-19. This study evaluates the CT patterns of residual abnormalities in severe COVID-19 pneumonia survivors. All consecutive COVID-19 survivors who received a CT scan 5–7...

  • Case Report
  • Open Access
8 Citations
5,199 Views
12 Pages

Breath-Hold Diving-Related Decompression Sickness with Brain Involvement: From Neuroimaging to Pathophysiology

  • José Manuel Sánchez-Villalobos,
  • María Lorenza Fortuna-Alcaraz,
  • Laura Serrano-Velasco,
  • Ángel Pujante-Escudero,
  • Carmen María Garnés-Sánchez,
  • Jorge Edverto Pérez-Garcilazo,
  • Agustín Olea-González and
  • José Antonio Pérez-Vicente

19 April 2022

Central nervous system involvement related to decompression sickness (DCS) is a very rare complication of breath-hold diving. So far, it has been postulated that repeated dives with short surface intervals represent a key factor in the development of...

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Tomography - ISSN 2379-139X