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Veterinary Sciences, Volume 6, Issue 2

June 2019 - 24 articles

Cover Story: Cytokines are produced by both cancer cells and the tumour microenvironment, and play an important role in many processes underlining cancer growth and progression, including but not limited to angiogenesis, cell proliferation, and cell adhesion. Using a comparative approach, this review explores the pro- and occasionally anti-tumourigenic potential of cytokines in those canine tumours that are considered excellent translational models: lymphoma, osteosarcoma, mammary gland tumours, and melanoma. In veterinary oncology, cytokines may thus provide a reliable contribution in setting up new screening tests, defining the prognostic signature of selected cancers and designing new therapeutic strategies. View this paper
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Articles (24)

  • Article
  • Open Access
6 Citations
5,031 Views
9 Pages

Mycobacterium avium subsp. paratuberculosis ELISA Responses in Milk Samples from Vaccinated and Nonvaccinated Dairy Goat Herds in The Netherlands

  • Saskia Luttikholt,
  • Karianne Lievaart-Peterson,
  • Maaike Gonggrijp,
  • Marian Aalberts,
  • Gerdien van Schaik and
  • Piet Vellema

The aims of our study were to calculate the most appropriate cut-off value for milk samples in a serum-validated Mycobacterium avium subsp. paratuberculosis (MAP) ELISA and to analyze MAP ELISA responses in milk samples from vaccinated and nonvaccina...

  • Communication
  • Open Access
46 Citations
6,495 Views
9 Pages

This survey was conducted to investigate the contamination by multiple mycotoxins, aflatoxins (AFB1, AFB2, AFG1, and AFG2), ochratoxin A (OTA), and zearalenone (ZEA) in 61 samples of maize and 17 commercial animal feed samples, and of aflatoxin M1 (A...

  • Case Report
  • Open Access
4 Citations
6,404 Views
9 Pages

A twelve-year-old male castrated Chihuahua with a severe, microcytic, hypochromic, and nonregenerative direct antiglobulin test positive anemia characterized by marked spherocytosis was referred to the veterinary hospital. Abdominal ultrasound reveal...

  • Case Report
  • Open Access
27 Citations
6,224 Views
6 Pages

Characterisation of the First Bovine Parainfluenza Virus 3 Isolate Detected in Cattle in Turkey

  • Harun Albayrak,
  • Zafer Yazici,
  • Emre Ozan,
  • Cuneyt Tamer,
  • Ahmed Abd El Wahed,
  • Stefanie Wehner,
  • Kristina Ulrich and
  • Manfred Weidmann

A respiratory disease outbreak on a cattle farm in northern Turkey produced respiratory tract symptoms and severe pneumonia symptoms in 20 calves. Eight calves died, and a lung specimen from one carcass was analysed for bacteria and for viruses of th...

  • Article
  • Open Access
20 Citations
6,074 Views
19 Pages

A prior study in bovine mammary (MACT) cells indicated that long-chain fatty acids (LCFA) C16:0 and C18:0, but not unsaturated LCFA, control transcription of milk fat-related genes partly via the activation of peroxisome proliferator-activated recept...

  • Communication
  • Open Access
21 Citations
7,216 Views
8 Pages

Canine mast cell tumours (MCTs) present a wide variety of challenging clinical behaviours in terms of predicting the prognosis and choosing appropriate treatment. This study investigated the frequency, risk, and prognostic factors of MCTs in dogs adm...

  • Article
  • Open Access
3 Citations
5,462 Views
17 Pages

2,4-Thiazolidinedione in Well-Fed Lactating Dairy Goats: II. Response to Intra-Mammary Infection

  • Fernanda Rosa,
  • Misagh Moridi,
  • Johan S. Osorio,
  • Jayant Lohakare,
  • Erminio Trevisi,
  • Shelby Filley,
  • Charles Estill and
  • Massimo Bionaz

In a prior experiment, treatment of goats with the putative PPARγ agonist 2,4-thiazolidinedione (2,4-TZD) ameliorated the response to intramammary infection without evidence of PPARγ activation. The lack of PPARγ activation was poss...

  • Case Report
  • Open Access
3 Citations
5,586 Views
6 Pages

A seven-year-old spayed female Labrador retriever presented for necropsy following an acute history of thrombocytopenia, anemia, leukocytosis and abdominal effusion. A 2 × 3 × 10 cm, cylindrical to tubular, mottled red-to-tan mass extende...

  • Brief Report
  • Open Access
4,366 Views
6 Pages

Recent reports suggest that antibiotic therapy may either reduce or enhance the immune response to various porcine vaccines. Based upon these findings, we asked if antibiotic therapy alters immune cell populations, as measured by flow cytometry and/o...

  • Feature Paper
  • Article
  • Open Access
3 Citations
6,128 Views
11 Pages

Mortality Patterns in a Commercial Wean-To Finish Swine Production System

  • Samantha Mehling,
  • Alexandra Henao-Diaz,
  • Jeremy Maurer,
  • Ed Kluber,
  • Rachel Stika,
  • Christopher Rademacher,
  • Jeff Zimmerman,
  • Luis Giménez-Lirola,
  • Chong Wang and
  • Derald J. Holtkamp
  • + 6 authors

Modern commercial pig production is a complex process that requires successful producers to understand and resolve factors associated with perturbations in production. One important perturbation is inventory loss due to mortality. In this study, data...

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Vet. Sci. - ISSN 2306-7381