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Bioengineering, Volume 9, Issue 7

July 2022 - 68 articles

Cover Story: Hydrogels have been widely used for various biomedical applications. In particular, gelatin methacryloyl (GelMA)-based hydrogel has been extensively investigated as a promising biomaterial candidate for musculoskeletal tissue regeneration. In addition to its biocompatibility and ease of synthesis, the ability to use it as a therapeutic cargo carrier, and its compatibility with different biofabrication platforms, it can be used alone or in combination with other biomaterials to enhance tissue repair. View this paper
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Articles (68)

  • Article
  • Open Access
16 Citations
5,125 Views
9 Pages

Shock Acceleration and Attenuation during Running with Minimalist and Maximalist Shoes: A Time- and Frequency-Domain Analysis of Tibial Acceleration

  • Liangliang Xiang,
  • Yaodong Gu,
  • Ming Rong,
  • Zixiang Gao,
  • Tao Yang,
  • Alan Wang,
  • Vickie Shim and
  • Justin Fernandez

Tibial shock attenuation is part of the mechanism that maintains human body stabilization during running. It is crucial to understand how shock characteristics transfer from the distal to proximal joint in the lower limb. This study aims to investiga...

  • Review
  • Open Access
12 Citations
8,193 Views
19 Pages

Paradoxical Duel Role of Collagen in Rheumatoid Arthritis: Cause of Inflammation and Treatment

  • Jeevithan Elango,
  • Camilo Zamora-Ledezma,
  • Baolin Ge,
  • Chunyu Hou,
  • Zhilin Pan,
  • Bin Bao,
  • Carlos Pérez Albacete Martínez,
  • José Manuel Granero Marín,
  • José Eduardo Maté Sánchez de Val and
  • Chunling Bao
  • + 1 author

In biology, collagen-biomaterial regulates several signaling mechanisms of bone and immune cells involved in tissue repair and any imbalance in collagen turnover may affect the homeostasis of cells, becoming a major cause of several complications. In...

  • Review
  • Open Access
48 Citations
6,475 Views
28 Pages

Nano-Based Theranostic Platforms for Breast Cancer: A Review of Latest Advancements

  • Rabia Arshad,
  • Maria Hassan Kiani,
  • Abbas Rahdar,
  • Saman Sargazi,
  • Mahmood Barani,
  • Shirin Shojaei,
  • Muhammad Bilal,
  • Deepak Kumar and
  • Sadanand Pandey

Breast cancer (BC) is a highly metastatic multifactorial disease with various histological and molecular subtypes. Due to recent advancements, the mortality rate in BC has improved over the past five decades. Detection and treatment of many cancers a...

  • Article
  • Open Access
7 Citations
5,214 Views
14 Pages

Development of a Modular Tissue Phantom for Evaluating Vascular Access Devices

  • Emily N. Boice,
  • David Berard,
  • Jose M. Gonzalez,
  • Sofia I. Hernandez Torres,
  • Zechariah J. Knowlton,
  • Guy Avital and
  • Eric J. Snider

Central vascular access (CVA) may be critical for trauma care and stabilizing the casualty. However, it requires skilled personnel, often unavailable during remote medical situations and combat casualty care scenarios. Automated CVA medical devices h...

  • Article
  • Open Access
10 Citations
3,774 Views
20 Pages

The Effect of Mesenchymal Stem Cells, Adipose Tissue Derived Stem Cells, and Cellular Stromal Vascular Fraction on the Repair of Acute Anal Sphincter Injury in Rats

  • Wenbin Chen,
  • Zijian He,
  • Shuyu Li,
  • Zixin Wu,
  • Jin Tan,
  • Weifeng Yang,
  • Guanwei Li,
  • Xiaoting Pan,
  • Yuying Liu and
  • Feng-Juan Lyu
  • + 1 author

Background: Anal sphincter incontinence (ASI) can cause a serious decline in the quality of life and can cause a socioeconomic burden. Studies have shown that bone marrow mesenchymal stem cells (MSC) have significant therapeutic effects on ASI, but t...

  • Article
  • Open Access
7 Citations
3,868 Views
19 Pages

Development of an In Vivo Model for Eustachian Tube Dysfunction

  • Niels Oppel,
  • Malena Ezzat,
  • Philipp Krüger,
  • Katharina Schmitt,
  • Alexandra Napp,
  • Friederike Pohl,
  • Andre Bleich,
  • Thomas Lenarz,
  • Tobias Stein and
  • Gerrit Paasche
  • + 1 author

Otitis media is often connected to Eustachian tube dysfunction (ETD). Until now, there was no large animal model available for the examination of new treatment methods such as stents for the Eustachian tube (ET). Thus, the aim of the study was to dev...

  • Article
  • Open Access
12 Citations
4,109 Views
20 Pages

Background: Midpalatal suture maturation and ossification status is the basis for appraising maxillary transverse developmental status. Methods: We established a midpalatal suture cone-beam computed tomography (CBCT) normalized database of the growth...

  • Article
  • Open Access
12 Citations
4,084 Views
18 Pages

Quantification of Intra-Muscular Adipose Infiltration in Calf/Thigh MRI Using Fully and Weakly Supervised Semantic Segmentation

  • Rula Amer,
  • Jannette Nassar,
  • Amira Trabelsi,
  • David Bendahan,
  • Hayit Greenspan and
  • Noam Ben-Eliezer

Purpose: Infiltration of fat into lower limb muscles is one of the key markers for the severity of muscle pathologies. The level of fat infiltration varies in its severity across and within patients, and it is traditionally estimated using visual rad...

  • Article
  • Open Access
5 Citations
3,076 Views
8 Pages

Sealing Ability of Bioactive Root-End Filling Materials in Retro Cavities Prepared with Er,Cr:YSGG Laser and Ultrasonic Techniques

  • Ivona Bago,
  • Ružica Lucić,
  • Ana Budimir,
  • Valentina Rajić,
  • Merima Balić and
  • Ivica Anić

The aim of this in vitro study was to compare the apical sealing ability of total fill bioceramic root repair material (BC-RRM) and mineral trioxide aggregate (MTA), regarding the retrograde preparation technique used: ultrasonic or erbium, chromium:...

  • Brief Report
  • Open Access
3 Citations
2,476 Views
10 Pages

Dense collagen hydrogels are promising biomaterials for several tissue-engineering applications. They exhibit high mechanical properties, similar to physiological extracellular matrices, and do not shrink under cellular activity. However, they suffer...

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Bioengineering - ISSN 2306-5354