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Bioengineering, Volume 9, Issue 3

March 2022 - 43 articles

Cover Story: The word “microbiota” refers to all the microorganisms that reside within the human body. An alteration of the human gut microbiota composition seems to have a relevant role in the development of several diseases, ranging from dementia to autism, from renal (e.g., pyelonephritis) to hepatic diseases (non-alcoholic fatty liver disease). Fabricating an in vitro model of the human gut microbiota is an enabling step to shed light on the intricate relationship between microorganisms and human host. Here, we present a novel approach to the culture of the human gut microbiota using an electrospun scaffold to support the adhesion and proliferation of microorganisms. View this paper
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Articles (43)

  • Article
  • Open Access
5 Citations
4,902 Views
15 Pages

Modular Bioreactor Design for Directed Tendon/Ligament Tissue Engineering

  • Axel J. Delakowski,
  • Jared D. Posselt and
  • Christopher T. Wagner

Functional tissue-engineered tendons and ligaments remain to be prepared in a reproducible and scalable manner. This study evaluates an acellular 3D extracellular matrix (ECM) scaffold for tendon/ligament tissue engineering and their ability to suppo...

  • Article
  • Open Access
10 Citations
5,700 Views
13 Pages

Three-dimensional cell culture has been extensively involved in biomedical applications due to its high availability and relatively mature biochemical properties. However, single 3D cell culture models based on hydrogel or various scaffolds do not me...

  • Article
  • Open Access
11 Citations
4,542 Views
26 Pages

Volatile fatty acid (VFA) rich streams from fermentation of organic residuals and wastewater are suitable feedstocks for mixed microbial culture (MMC) Polyhydroxyalkanoate (PHA) production. However, many such streams have low total VFA concentration...

  • Article
  • Open Access
33 Citations
5,530 Views
14 Pages

LASSO Regression Modeling on Prediction of Medical Terms among Seafarers’ Health Documents Using Tidy Text Mining

  • Nalini Chintalapudi,
  • Ulrico Angeloni,
  • Gopi Battineni,
  • Marzio di Canio,
  • Claudia Marotta,
  • Giovanni Rezza,
  • Getu Gamo Sagaro,
  • Andrea Silenzi and
  • Francesco Amenta

Generally, seafarers face a higher risk of illnesses and accidents than land workers. In most cases, there are no medical professionals on board seagoing vessels, which makes disease diagnosis even more difficult. When this occurs, onshore doctors ma...

  • Review
  • Open Access
30 Citations
9,125 Views
15 Pages

Disinfection Procedures and Their Effect on the Microorganism Colonization of Dental Impression Materials: A Systematic Review and Meta-Analysis of In Vitro Studies

  • Louis Hardan,
  • Rim Bourgi,
  • Carlos Enrique Cuevas-Suárez,
  • Monika Lukomska-Szymanska,
  • Elizabeth Cornejo-Ríos,
  • Vincenzo Tosco,
  • Riccardo Monterubbianesi,
  • Sara Mancino,
  • Ammar Eid and
  • Davide Mancino
  • + 2 authors

Dental impressions are contaminated with potentially pathogenic microorganisms when they come into contact with patient blood, saliva, and plaque. Numerous disinfectants are used; however, no sole disinfectant can be designated as universal for all t...

  • Article
  • Open Access
21 Citations
6,499 Views
11 Pages

Cell Retention as a Viable Strategy for PHA Production from Diluted VFAs with Bacillus megaterium

  • Milos Kacanski,
  • Lukas Pucher,
  • Carlota Peral,
  • Thomas Dietrich and
  • Markus Neureiter

The production of biodegradable and biocompatible materials such as polyhydroxyalkanoates (PHAs) from waste-derived volatile fatty acids (VFAs) is a promising approach towards implementing a circular bioeconomy. However, VFA solutions obtained via ac...

  • Review
  • Open Access
52 Citations
10,852 Views
25 Pages

Present Application and Perspectives of Organoid Imaging Technology

  • Keyi Fei,
  • Jinze Zhang,
  • Jin Yuan and
  • Peng Xiao

An organoid is a miniaturized and simplified in vitro model with a similar structure and function to a real organ. In recent years, the use of organoids has increased explosively in the field of growth and development, disease simulation, drug screen...

  • Article
  • Open Access
25 Citations
4,209 Views
11 Pages

A Study on Lower Limb Asymmetries in Parkinson’s Disease during Gait Assessed through Kinematic-Derived Parameters

  • Federico Arippa,
  • Bruno Leban,
  • Marco Monticone,
  • Giovanni Cossu,
  • Carlo Casula and
  • Massimiliano Pau

Unilaterality of motor symptoms is a distinctive feature of Parkinson’s Disease (PD) and represents an important co-factor involved in motor deficits and limitations of functional abilities including postural instability and asymmetrical gait....

  • Article
  • Open Access
8 Citations
3,194 Views
12 Pages

Meniscus Matrix Structural and Biomechanical Evaluation: Age-Dependent Properties in a Swine Model

  • Lucia Aidos,
  • Silvia Clotilde Modina,
  • Valentina Rafaela Herrera Millar,
  • Giuseppe Maria Peretti,
  • Laura Mangiavini,
  • Marco Ferroni,
  • Federica Boschetti and
  • Alessia Di Giancamillo

The analysis of the morphological, structural, biochemical, and mechanical changes of the Extracellular Matrix (ECM), which occur during meniscus development, represents the goal of the present study. Medial fully developed menisci (FD, 9-month-old p...

  • Article
  • Open Access
15 Citations
2,938 Views
7 Pages

Hypertension (HTN) is a leading risk factor for cardiovascular (CV) disease. Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are thought to be actively involved in the remodeling of the CV extracellular matrix (ECM) during hypert...

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Bioengineering - ISSN 2306-5354