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Toxics, Volume 9, Issue 12

December 2021 - 44 articles

Cover Story: We investigated the association of prenatal co-exposure to organochlorines and metals with cognitive flexibility among a diverse group of adolescents living near a Superfund site in Massachusetts. We observed adverse associations of the chemical mixture and manganese with the Delis Kaplan Executive Function System Trail-Making and Color-Word Interference measures of cognitive flexibility. This study is among the first to provide evidence of an adverse association of prenatal exposure to a chemical mixture with cognitive flexibility in adolescence, a time of substantial executive function development. View this paper.
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Articles (44)

  • Article
  • Open Access
6 Citations
4,123 Views
13 Pages

Diacetyl Vapor Inhalation Induces Mixed, Granulocytic Lung Inflammation with Increased CD4+CD25+ T Cells in the Rat

  • Emma L. House,
  • So-Young Kim,
  • Carl J. Johnston,
  • Angela M. Groves,
  • Eric Hernady,
  • Ravi S. Misra and
  • Matthew D. McGraw

20 December 2021

Diacetyl (DA) is a highly reactive alpha diketone associated with flavoring-related lung disease. In rodents, acute DA vapor exposure can initiate an airway-centric, inflammatory response. However, this immune response has yet to be fully characteriz...

  • Review
  • Open Access
152 Citations
17,075 Views
19 Pages

Heavy Metal Accumulation in Rice and Aquatic Plants Used as Human Food: A General Review

  • Mohammad Main Uddin,
  • Mohamed Cassim Mohamed Zakeel,
  • Junaida Shezmin Zavahir,
  • Faiz M. M. T. Marikar and
  • Israt Jahan

20 December 2021

Aquatic ecosystems are contaminated with heavy metals by natural and anthropogenic sources. Whilst some heavy metals are necessary for plants as micronutrients, others can be toxic to plants and humans even in trace concentrations. Among heavy metals...

  • Feature Paper
  • Article
  • Open Access
3 Citations
3,067 Views
12 Pages

17 December 2021

Because of the unique geographical, climate, and anthropogenic emission characteristics, it is meaningful to explore the air pollution in the Harbin-Changchun (HC) metropolitan area. In this study, the Air Quality Index (AQI) and the corresponding ma...

  • Article
  • Open Access
14 Citations
3,347 Views
18 Pages

17 December 2021

Wuhan was locked down from 23 January to 8 April 2020 to prevent the spread of the novel coronavirus disease 2019 (COVID-19). Both public and private transportation in Wuhan and its neighboring cities in Hubei Province were suspended or restricted, a...

  • Feature Paper
  • Case Report
  • Open Access
11 Citations
3,709 Views
9 Pages

Forensic Toxicological and Medico-Legal Evaluation in a Case of Incongruous Drug Administration in Terminal Cancer Patients

  • Pascale Basilicata,
  • Pasquale Giugliano,
  • Giuseppe Vacchiano,
  • Angela Simonelli,
  • Rossella Guadagni,
  • Angela Silvestre and
  • Maria Pieri

16 December 2021

Background: In most cases, palliative care is prescribed to adults diagnosed with cancer. The definition of the most suitable therapy for an effective sedation in terminal cancer patients still represents one of the most challenging goals in medical...

  • Article
  • Open Access
5 Citations
3,508 Views
11 Pages

The Research of Toxicity and Sensitization Potential of PEGylated Silver and Gold Nanomaterials

  • Dong-Han Lee,
  • Seo-Yoon Choi,
  • Ki-Kyung Jung,
  • Jun-Young Yang,
  • Ja-young Jeong,
  • Jae-Ho Oh,
  • Sung-Hyun Kim and
  • Jin-Hee Lee

16 December 2021

Polyethylene glycol (PEG) is a polymer used for surface modification of important substances in the modern pharmaceutical industry and biopharmaceutical fields. Despite the many benefits of PEGylation, there is also the possibility that the applicati...

  • Article
  • Open Access
11 Citations
4,610 Views
14 Pages

15 December 2021

To clarify the influence of dioxin exposure on brain morphometry, the present study investigated associations between dioxin exposure at high levels and brain structural irregularities in 32 Vietnamese men. Two exposure markers were used: blood dioxi...

  • Article
  • Open Access
11 Citations
4,813 Views
11 Pages

Toxicity Assessment of a Single Dose of Poly(ethylene glycol) Diglycidyl Ether (PEGDE) Administered Subcutaneously in Mice

  • Do-Hyun Kim,
  • Jong-Hyeon Han,
  • Hyuk-Cheol Kwon,
  • Su-Jin Lim,
  • Seo-Gu Han,
  • Hyun-Su Jung,
  • Keyong-Ho Lee,
  • Ju-Hee Kang and
  • Sung-Gu Han

15 December 2021

Poly(ethylene glycol) diglycidyl ether (PEGDE) is widely used to cross-link polymers, particularly in the pharmaceutical and biomaterial sectors. However, the subcutaneous toxicity of PEGDE has not yet been assessed. PEGDE samples (500–40,000 &...

  • Feature Paper
  • Article
  • Open Access
4 Citations
3,208 Views
11 Pages

Spatially and Temporally Resolved Ambient PM2.5 in Relation to Preterm Birth

  • Whitney Cowell,
  • Elena Colicino,
  • Xueying Zhang,
  • Rachel Ledyard,
  • Heather H. Burris,
  • Michele R. Hacker,
  • Itai Kloog,
  • Allan Just,
  • Robert O. Wright and
  • Rosalind J. Wright

14 December 2021

Growing evidence suggests that maternal exposure to ambient fine particulate matter (PM2.5) during pregnancy is associated with preterm birth; however, few studies have examined critical windows of exposure, which can help elucidate underlying biolog...

  • Article
  • Open Access
12 Citations
3,516 Views
12 Pages

Association between Levels of Urine Di-(2-ethylhexyl)phthalate Metabolites and Heart Rate Variability in Young Adults

  • Ching-Way Chen,
  • Shu-Yu Tang,
  • Jin-Shiang Hwang,
  • Chang-Chuan Chan,
  • Cheng-Chih Hsu,
  • Chien-Yu Lin and
  • Ta-Chen Su

12 December 2021

Phthalate exposure is associated with cardiovascular risk. Among the various phthalates, di-(2-ethylhexyl) phthalate (DEHP) is a deleterious plasticizer in our daily lives. This study investigated the association between DEHP exposure and the alterat...

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Toxics - ISSN 2305-6304