Special Issue "Update Reproductive Toxicology Research Associated with Air Pollutions"

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Toxicology".

Deadline for manuscript submissions: 31 October 2021.

Special Issue Editor

Prof. Dr. Stefan Hansson
E-Mail Website
Guest Editor
Inst. Clinical Sciences Lund, Dep Obstetrics and Gynecology, Lund University, Lund, Sweden
Interests: placenta function; preeclampsia; air pollution

Special Issue Information

Dear Colleagues,

Recent findings have demonstrated an association between exposure to air pollutants and an increased risk of developing preeclampsia (PE). Air pollution in low- and middle-income countries (LMIC) is a tremendous health problem, where exposure to airborne particle matter < 2.5 µm (PM2.5), both outdoors and indoors, is much higher than the health limit value of 10 µg/m3 suggested by the WHO, thus posing a significant threat to human health in general and to pregnant women in particular. At the same time, these countries have the highest maternal mortality rate in the world. Preeclampsia is a leading cause of maternal and perinatal morbidity and mortality, responsible for about 18% of all maternal deaths and up to 40% of neonatal deaths. Recent findings have demonstrated an association between exposure to air pollutants and an increased risk of developing PE. Evidence indicates that exposure to pollutants in general and air pollution specifically induces oxidative stress and consequently inflammation. Furthermore, exposure to PM is associated with mitochondrial oxidative DNA damage both in normal state and in pregnancy, resulting in increased systemic oxidative stress in blood and placenta. Increased insight into pregnancy outcome in relation to pollutants exposure is crucial to combat an increasing problem on maternal and child health and morbidity in general and in LMIC in particular.

The overarching aim of this Special Issue is to highlight the negative effects of environmental factors and air pollution during pregnancy. Increased insight into pregnancy outcomes in relation to air pollution exposure is crucial to combat an increasing air pollution problem on maternal and child health and long-term morbidity.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following theme: air pollution and environmental toxins in relation to placental function, pregnancy outcomes, long-term maternal and fetal morbidity. The articles may span from molecular to epidemiological aspects of the main theme.

I look forward to receiving your contributions.

Prof. Dr. Stefan Hansson
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • implantation
  • placenta
  • syncytiotrophoblast
  • oxidative stress
  • inflammation
  • miscarriage
  • fetal growth restriction
  • preeclampsia
  • cardiovascular disease
  • air pollution

Published Papers

This special issue is now open for submission.
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