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Case Report

Overdose of Quetiapine—A Case Report with QT Prolongation

Research Unit U.R.I.To.N., University of Firenze, 50134 Firenze, Italy
Forensic Toxicology Division, Department of Health Sciences, University of Firenze, 50134 Firenze, Italy
Department of Health Promotion, Maternal Child Care and Medical Specialties, University of Palermo, 90151 Palermo, Italy
Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy
School of Specialization of Legal Medicine, University Hospital of Padova, Via Falloppio 50, 35121 Padova, Italy
Legal Medicine and Toxicology, University Hospital of Padova, Via Falloppio 50, 35121 Padova, Italy
Author to whom correspondence should be addressed.
Academic Editor: Guido Cavaletti
Toxics 2021, 9(12), 339;
Received: 25 October 2021 / Revised: 30 November 2021 / Accepted: 4 December 2021 / Published: 7 December 2021
(This article belongs to the Special Issue Poisoning Caused by Medicines and Drugs of Abuse)
Quetiapine is an atypical antipsychotic drug used to treat bipolar disorder, schizophrenia, and major depressive disorder. Although several studies describe the adverse effects of intoxication with Quetiapine, only a few report an extreme overdose without comedications that lead to a life threat. We present a case of a 75-year-old male who tried to attempt suicide by ingesting 28 g of Quetiapine. During the management in the emergency department, both serum and urine samples were collected, allowing a complete pharmacokinetic analysis to be conducted, from the admission to the discharge. View Full-Text
Keywords: quetiapine; intoxication; QT-prolongation quetiapine; intoxication; QT-prolongation
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MDPI and ACS Style

Bertol, E.; Vaiano, F.; Argo, A.; Zerbo, S.; Trignano, C.; Protani, S.; Favretto, D. Overdose of Quetiapine—A Case Report with QT Prolongation. Toxics 2021, 9, 339.

AMA Style

Bertol E, Vaiano F, Argo A, Zerbo S, Trignano C, Protani S, Favretto D. Overdose of Quetiapine—A Case Report with QT Prolongation. Toxics. 2021; 9(12):339.

Chicago/Turabian Style

Bertol, Elisabetta, Fabio Vaiano, Antonina Argo, Stefania Zerbo, Claudia Trignano, Simone Protani, and Donata Favretto. 2021. "Overdose of Quetiapine—A Case Report with QT Prolongation" Toxics 9, no. 12: 339.

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