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Processes, Volume 6, Issue 5

2018 May - 24 articles

Cover Story: The prognosis is grim for patients who have metastasis, where cancer cells spread from a localized tumor to other regions in the body. Cancer cells and the surrounding extracellular matrix (ECM) interact to facilitate migration of cancer cells during early metastasis. Cancer cells secrete particular enzymes to cut and align collagen fibers of the ECM. These ECM remodeling activities transform the ECM from a random fiber matrix into an oriented "fibrous highway" that enhances cancer cell migration. This paper addresses remodeling of the ECM during metastasis via mathematical modeling using partial differential equations. View this paper.
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Articles (24)

  • Article
  • Open Access
23 Citations
7,702 Views
21 Pages

22 May 2018

Critical infrastructure such as power and water delivery is growing rapidly in the developing world and there are developed assets that must be maintained in developed nations. One underground component that is difficult to inspect is water supply pi...

  • Feature Paper
  • Article
  • Open Access
2 Citations
5,513 Views
22 Pages

21 May 2018

Due to insufficient endogenous production of erythropoietin, chronic kidney disease patients with anemia are often treated by the administration of recombinant human erythropoietin (EPO). The target of the treatment is to keep the patient’s hemoglobi...

  • Article
  • Open Access
51 Citations
9,523 Views
14 Pages

A Facile Synthesis of Hexagonal Spinel λ-MnO2 Ion-Sieves for Highly Selective Li+ Adsorption

  • Fan Yang,
  • Sichong Chen,
  • Chentao Shi,
  • Feng Xue,
  • Xiaoxian Zhang,
  • Shengui Ju and
  • Weihong Xing

17 May 2018

Ion-sieves are a class of green adsorbent for extraction Li+ from salt lakes. Here, we propose a facile synthesis of hexagonal spinel LiMn2O4 (LMO) precursor under mild condition which was first prepared via a modified one-pot reduction hydrothermal...

  • Article
  • Open Access
29 Citations
7,334 Views
17 Pages

16 May 2018

Medical data classification is an important factor in improving diagnosis and treatment and can assist physicians in making decisions about serious diseases by collecting symptoms and medical analyses. In this work, hybrid classification optimization...

  • Feature Paper
  • Article
  • Open Access
22 Citations
11,262 Views
16 Pages

16 May 2018

The spreading of cancer cells, also known as metastasis, is a lethal hallmark in cancer progression and the primary cause of cancer death. Recent cancer research has suggested that the remodeling of collagen fibers in the extracellular matrix (ECM) o...

  • Feature Paper
  • Review
  • Open Access
16 Citations
7,537 Views
23 Pages

The Spectrum of Mechanism-Oriented Models and Methods for Explanations of Biological Phenomena

  • C. Anthony Hunt,
  • Ahmet Erdemir,
  • William W. Lytton,
  • Feilim Mac Gabhann,
  • Edward A. Sander,
  • Mark K. Transtrum and
  • Lealem Mulugeta

14 May 2018

Developing and improving mechanism-oriented computational models to better explain biological phenomena is a dynamic and expanding frontier. As the complexity of targeted phenomena has increased, so too has the diversity in methods and terminologies,...

  • Review
  • Open Access
111 Citations
17,515 Views
15 Pages

12 May 2018

The growing demand for lithium necessitates the development of an efficient process to recover it from three kinds of solutions, namely brines as well as acid and alkaline leach liquors of primary and secondary resources. Therefore, the separation of...

  • Article
  • Open Access
16 Citations
5,732 Views
14 Pages

11 May 2018

The ampholytic chitosan based flocculant carboxylated chitosan graft-(3-chloro-2-hydroxypropyl) trimethylammonium chloride-dimethyl diallyl ammonium chloride (CPCTS-g-P (CTA-DMDAAC)) was synthesized by photo polymerization using carboxylated chitosan...

  • Feature Paper
  • Article
  • Open Access
22 Citations
14,139 Views
21 Pages

A Systematic Framework for Data Management and Integration in a Continuous Pharmaceutical Manufacturing Processing Line

  • Huiyi Cao,
  • Srinivas Mushnoori,
  • Barry Higgins,
  • Chandrasekhar Kollipara,
  • Adam Fermier,
  • Douglas Hausner,
  • Shantenu Jha,
  • Ravendra Singh,
  • Marianthi Ierapetritou and
  • Rohit Ramachandran

10 May 2018

As the pharmaceutical industry seeks more efficient methods for the production of higher value therapeutics, the associated data analysis, data visualization, and predictive modeling require dependable data origination, management, transfer, and inte...

  • Feature Paper
  • Article
  • Open Access
35 Citations
8,289 Views
26 Pages

8 May 2018

Shale gas production is associated with significant usage of fresh water and discharge of wastewater. Consequently, there is a necessity to create proper management strategies for water resources in shale gas production and to integrate conventional...

  • Article
  • Open Access
34 Citations
4,854 Views
14 Pages

7 May 2018

Gob-side entry retaining (GER) employed in a thin coal seam (TCS) can increase economic benefits and coal recovery, as well as mitigate gas concentration in the gob. In accordance with the caving style of a limestone roof, the gas concentration and a...

  • Article
  • Open Access
36 Citations
8,143 Views
17 Pages

5 May 2018

A lab-scale of a side stream anaerobic membrane bioreactor (AnMBR) equipped with a tubular membrane operated at the mesophilic temperature of 37.0 ± 1.2 °C for treating domestic wastewater was tested to investigate its performance and foul...

  • Article
  • Open Access
27 Citations
5,932 Views
13 Pages

3 May 2018

Due to the complex formation process of a rock mass, a large number of fissures, joints, faults, other defects exist and the defects commonly contain infilled materials. The jointed rock masses are in a complex geological environment, in which the ge...

  • Article
  • Open Access
8 Citations
5,520 Views
12 Pages

1 May 2018

This study explores the possible use of ionic liquids as a solvent in a commercial high-pressure CO2 removal process, to gain environmental and energy benefits. There are two main constraints in realizing this: ionic liquids can be corrosive, specifi...

  • Article
  • Open Access
15 Citations
4,964 Views
16 Pages

1 May 2018

Recently, the Internet has been utilized by many applications to convey time-sensitive messages. The persistently expanding Internet coverage and its easy accessibility have offered to ascend to a problem which was once regarded as not essential to c...

  • Feature Paper
  • Article
  • Open Access
7 Citations
5,541 Views
13 Pages

Substrate Effect on Carbon/Ceramic Mixed Matrix Membrane Prepared by a Vacuum-Assisted Method for Desalination

  • Yingjun Song,
  • Julius Motuzas,
  • David K. Wang,
  • Greg Birkett,
  • Simon Smart and
  • João C. Diniz da Costa

1 May 2018

This work investigates the effect of various membrane substrates and coating conditions on the formation of carbon/ceramic mixed matrix membranes for desalination application. The substrates were impregnated with phenolic resin via a vacuum-assisted...

  • Article
  • Open Access
38 Citations
8,481 Views
25 Pages

1 May 2018

A mathematical model for a transmission of TB-HIV/AIDS co-infection that incorporates prevalence dependent behaviour change in the population and treatment for the infected (and infectious) class is formulated and analyzed. The two sub-models, when e...

  • Feature Paper
  • Article
  • Open Access
23 Citations
7,569 Views
14 Pages

ADAR Mediated RNA Editing Modulates MicroRNA Targeting in Human Breast Cancer

  • Justin T. Roberts,
  • Dillon G. Patterson,
  • Valeria M. King,
  • Shivam V. Amin,
  • Caroline J. Polska,
  • Dominika Houserova,
  • Aline Crucello,
  • Emmaline C. Barnhill,
  • Molly M. Miller and
  • Glen M. Borchert
  • + 1 author

25 April 2018

RNA editing by RNA specific adenosine deaminase acting on RNA (ADAR) is increasingly being found to alter microRNA (miRNA) regulation. Editing of miRNA transcripts can affect their processing, as well as which messenger RNAs (mRNAs) they target. Furt...

  • Article
  • Open Access
5 Citations
5,062 Views
8 Pages

Recovery of Filtered Graphene Oxide Residue Using Elastic Gel Packed in a Column by Cross Flow

  • Yuji Takaoka,
  • Manoka Miyoshi,
  • Koichi Sakaguchi,
  • Shintaro Morisada,
  • Keisuke Ohto and
  • Hidetaka Kawakita

25 April 2018

To recover the filtered residues on a gel layer in a column, the method using the elasticity of the gel layer and flowing water in a cross-flow manner is proposed. Polymerized spherical gel (40 μm) was packed in a column to a set height of 0.7 cm....

  • Feature Paper
  • Article
  • Open Access
53 Citations
24,796 Views
27 Pages

Measuring Cellular Biomass Composition for Computational Biology Applications

  • Ashley E. Beck,
  • Kristopher A. Hunt and
  • Ross P. Carlson

24 April 2018

Computational representations of metabolism are increasingly common in medical, environmental, and bioprocess applications. Cellular growth is often an important output of computational biology analyses, and therefore, accurate measurement of biomass...

  • Article
  • Open Access
5 Citations
8,436 Views
10 Pages

24 April 2018

FluxVisualizer (Version 1.0, 2017, freely available at https://fluxvisualizer.ibgc.cnrs.fr) is a software to visualize fluxes values on a scalable vector graphic (SVG) representation of a metabolic network by colouring or increasing the width of reac...

  • Article
  • Open Access
12 Citations
5,777 Views
22 Pages

24 April 2018

This study investigated the heterogeneous Fenton treatment to process coalbed methane-produced water containing fracturing fluid and chose the development region of coalbed methane in the Southern Qinshui Basin as a research area. We synthesized the...

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Processes - ISSN 2227-9717