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Antibiotics, Volume 11, Issue 4

April 2022 - 113 articles

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Cover Story: We present the findings from active and passive antimicrobial resistance (AMR) surveillance studies from Canada and the USA from 2000 to 2021, focusing on Mannheimia haemolytica, Pasturella multocida, Histophilus somni, and Mycoplasma bovis as bacterial pathogens of bovine respiratory disease (BRD). The role of integrative and conjugative elements in the concentration and dissemination of AMR in BRD bacteria as well as the role of biofilms in increasing AMR are discussed. The high incidence of AMR in BRD bacteria isolated from morbid feedlot cattle highlights the need for the development of affordable point-of-care technologies that promote prudent antimicrobial use in the cattle industry. The most recent emerging technologies that may satisfy this need are also outlined in the manuscript. View this paper

Articles (113)

  • Article
  • Open Access
69 Citations
5,864 Views
12 Pages
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Impact of COVID-19 on Antimicrobial Consumption and Spread of Multidrug-Resistance in Bacterial Infections

  • Kibum Jeon,
  • Seri Jeong,
  • Nuri Lee,
  • Min-Jeong Park,
  • Wonkeun Song,
  • Han-Sung Kim,
  • Hyun Soo Kim and
  • Jae-Seok Kim
Antibiotics2022, 11(4), 535;https://doi.org/10.3390/antibiotics11040535

18 April 2022

The spread of COVID-19 pandemic may have affected antibiotic consumption patterns and the prevalence of colonized or infected by multidrug-resistant (MDR) bacteria. We investigated the differences in the consumption of antibiotics easily prone to res...

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  • Article
  • Open Access
16 Citations
5,496 Views
15 Pages
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Fecal Shedding of Multidrug Resistant Escherichia coli Isolates in Dogs Fed with Raw Meat-Based Diets in Brazil

  • Carolina Pantuzza Ramos,
  • Carolina Yumi Iceri Kamei,
  • Flávia Mello Viegas,
  • Jonata de Melo Barbieri,
  • João Luís Reis Cunha,
  • Yaovi Mahuton Gildas Hounmanou,
  • Fernanda Morcatti Coura,
  • Jordana Almeida Santana,
  • Francisco Carlos Faria Lobato and
  • Anders Miki Bojesen
  • + 1 author
Antibiotics2022, 11(4), 534;https://doi.org/10.3390/antibiotics11040534

17 April 2022

The practice of feeding dogs raw meat-based diets (RMBDs) is growing in several countries, and the risks associated with the ingestion of pathogenic and antimicrobial-resistant Escherichia coli in dogs fed these diets are largely unknown. We characte...

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  • Review
  • Open Access
36 Citations
6,553 Views
18 Pages
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Companion Animals—An Overlooked and Misdiagnosed Reservoir of Carbapenem Resistance

  • Joana Moreira da Silva,
  • Juliana Menezes,
  • Cátia Marques and
  • Constança Ferreira Pomba
Antibiotics2022, 11(4), 533;https://doi.org/10.3390/antibiotics11040533

17 April 2022

The dissemination of antimicrobial-resistance is a major global threat affecting both human and animal health. Carbapenems are human use β-lactams of last resort; thus. the dissemination of carbapenemase-producing (CP) bacteria creates severe li...

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  • Review
  • Open Access
44 Citations
7,919 Views
14 Pages
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Antibiotic Resistance of Salmonella Typhimurium Monophasic Variant 1,4,[5],12:i:-in China: A Systematic Review and Meta-Analysis

  • Xiaojie Qin,
  • Mingzhe Yang,
  • Hua Cai,
  • Yangtai Liu,
  • Leon Gorris,
  • Muhammad Zohaib Aslam,
  • Kai Jia,
  • Tianmei Sun,
  • Xiang Wang and
  • Qingli Dong
Antibiotics2022, 11(4), 532;https://doi.org/10.3390/antibiotics11040532

16 April 2022

Antibiotic resistance in Salmonella is a global public health problem. Salmonella enterica serovar 1,4,[5],12:i:- (S. 1,4,[5],12:i:-), a monophasic variant of Salmonella Typhmurium, is one of the leading Salmonella serovars in several countries. This...

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  • Article
  • Open Access
7 Citations
3,399 Views
17 Pages
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Effect of Danofloxacin Treatment on the Development of Fluoroquinolone Resistance in Campylobacter jejuni in Calves

  • Debora Brito Goulart,
  • Ashenafi Feyisa Beyi,
  • Zuowei Wu,
  • Mehmet Cemal Adiguzel,
  • Anastasia Schroeder,
  • Kritika Singh,
  • Changyun Xu,
  • Melda Meral Ocal,
  • Renee Dewell and
  • Grant A. Dewell
  • + 3 authors
Antibiotics2022, 11(4), 531;https://doi.org/10.3390/antibiotics11040531

15 April 2022

Campylobacter is a leading cause of foodborne gastroenteritis. Recent studies have indicated a rise in fluoroquinolone-resistant (FQ-R) Campylobacter in cattle, where FQ is used to control bovine respiratory disease (BRD). To assess the effect of dan...

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  • Communication
  • Open Access
11 Citations
3,487 Views
10 Pages
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Wild Duck (Anas platyrhynchos) as a Source of Antibiotic-Resistant Salmonella enterica subsp. diarizonae O58—The First Report in Poland

  • Joanna Pławińska-Czarnak,
  • Karolina Wódz,
  • Lidia Piechowicz,
  • Ewa Tokarska-Pietrzak,
  • Zbigniew Bełkot,
  • Janusz Bogdan,
  • Jan Wiśniewski,
  • Piotr Kwieciński,
  • Adam Kwieciński and
  • Krzysztof Anusz
Antibiotics2022, 11(4), 530;https://doi.org/10.3390/antibiotics11040530

15 April 2022

The “One Health” approach increasingly demonstrates the global spread of pathogenic microorganisms and their antimicrobial resistance in the environment, both in animals and humans. Salmonella enterica subsp. diarizonae is nowadays very o...

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  • Review
  • Open Access
37 Citations
6,000 Views
24 Pages
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Current Knowledge on Biomaterials for Orthopedic Applications Modified to Reduce Bacterial Adhesive Ability

  • Valeria Allizond,
  • Sara Comini,
  • Anna Maria Cuffini and
  • Giuliana Banche
Antibiotics2022, 11(4), 529;https://doi.org/10.3390/antibiotics11040529

15 April 2022

A significant challenge in orthopedics is the design of biomaterial devices that are able to perform biological functions by substituting or repairing various tissues and controlling bone repair when required. This review presents an overview of the...

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  • Article
  • Open Access
15 Citations
4,081 Views
14 Pages
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Discovery of MurA Inhibitors as Novel Antimicrobials through an Integrated Computational and Experimental Approach

  • Fangyuan Zhang,
  • Joshua Graham,
  • Tianhua Zhai,
  • Yanhong Liu and
  • Zuyi Huang
Antibiotics2022, 11(4), 528;https://doi.org/10.3390/antibiotics11040528

14 April 2022

The bacterial cell wall is essential for protecting bacteria from the surrounding environment and maintaining the integrity of bacteria cells. The MurA enzyme, which is an essential enzyme involved in bacterial cell wall synthesis, could be a good dr...

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  • Article
  • Open Access
14 Citations
7,769 Views
19 Pages
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Availability, Prices and Affordability of Antibiotics Stocked by Informal Providers in Rural India: A Cross-Sectional Survey

  • Meenakshi Gautham,
  • Rosalind Miller,
  • Sonia Rego and
  • Catherine Goodman
Antibiotics2022, 11(4), 523;https://doi.org/10.3390/antibiotics11040523

14 April 2022

Providers without formal training deliver healthcare and antibiotics across rural India, but little is known about the antibiotics that they stock. We conducted a cross-sectional survey of such informal providers (IPs) in two districts of West Bengal...

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  • Article
  • Open Access
5 Citations
2,995 Views
11 Pages
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Expression of Staphylococcal Virulence Genes In Situ in Human Skin and Soft Tissue Infections

  • Michael S. Pulia,
  • Jennifer Anderson,
  • Zhan Ye,
  • Noha S. Elsayed,
  • Thao Le,
  • Jacob Patitucci,
  • Krishna Ganta,
  • Matthew Hall,
  • Vineet K. Singh and
  • Sanjay K. Shukla
Antibiotics2022, 11(4), 527;https://doi.org/10.3390/antibiotics11040527

14 April 2022

Background: Staphylococcus aureus, the most common pathogen in skin and soft tissue infections (SSTI), harbors many well-characterized virulence genes. However, the expression of many of them in SSTIs is unknown. In this study, S. aureus virulence ge...

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