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Biosensors, Volume 15, Issue 2

February 2025 - 62 articles

Cover Story: The increasing resistance to carbapenems, an important sub-class of beta-lactam antibiotics, is a major concern in the healthcare community. Carbapenem resistant bacteria have been found in the environment and food supply chains, where it has the potential to infect humans through direct or indirect contact. Rapid detection for preventative and control measures should be developed. This study utilized a gold-nanoparticle-based plasmonic biosensor for the parallel detection of the carbapenem resistance genes blaNDM-1 and blaOXA-1. To explore the field portability, DNA extraction was completed using a boiling method. The results showed a correlation of measurements between a spectrophotometer and an RGB (visual) cellphone app with high selectivity and sensitivity, showing potential for point-of-care use. View this paper
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Articles (62)

  • Article
  • Open Access
3 Citations
1,884 Views
17 Pages

Signal Differentiation of Moving Magnetic Nanoparticles for Enhanced Biodetection and Diagnostics

  • Kee Young Hwang,
  • Dakota Brown,
  • Supun B. Attanayake,
  • Dan Luu,
  • Minh Dang Nguyen,
  • T. Randall Lee and
  • Manh-Huong Phan

17 February 2025

Magnetic nanoparticles are extensively utilized as markers/signal labelling in various biomedical applications. Detecting and distinguishing magnetic signals from similarly sized moving magnetic nanoparticles in microfluidic systems is crucial yet ch...

  • Review
  • Open Access
4 Citations
3,096 Views
23 Pages

SERS-Active Micro/Nanomachines for Biosensing

  • Chenbing Li,
  • Wenqing Zhang,
  • Kai Zheng and
  • Jianhe Guo

16 February 2025

Surface-enhanced Raman spectroscopy (SERS) has emerged as a powerful noninvasive analytical technique with widespread applications in biochemical analysis and biomedical diagnostics. The need for highly sensitive, reproducible, and efficient detectio...

  • Article
  • Open Access
1,626 Views
12 Pages

A Ratiometric Fluorescence Nano pH Biosensor for Live-Cell Imaging Using Cerasome

  • Zhongqiao Zhang,
  • Xiaoshan Luo,
  • Xuanbo Wang,
  • Meng Liu,
  • Xiuli Yue and
  • Zhaozhu Zheng

16 February 2025

The development of a robust and biocompatible pH-sensing platform is critical for monitoring intracellular processes and diagnosing diseases. Here, we present a smart ultrastable ratiometric fluorescence nano pH sensor based on silica-coated liposome...

  • Article
  • Open Access
2 Citations
1,702 Views
18 Pages

Equivalent Circuit Modeling and Analysis for Microfluidic Electrical Impedance Monitoring of Single-Cell Growth

  • Yingying Wang,
  • Haoran Wu,
  • Yulu Geng,
  • Zhao Zhang,
  • Jiaming Fu,
  • Jia Ouyang and
  • Zhen Zhu

14 February 2025

Microfluidics has significantly advanced the field of single-cell analysis, particularly in studies related to cell growth, division, and heterogeneity. Electrical impedance spectroscopy (EIS), a label-free and non-invasive biosensing technique, has...

  • Article
  • Open Access
2 Citations
1,995 Views
18 Pages

14 February 2025

Antimicrobial resistance (AMR) is a rapidly growing global concern resulting from the overuse of antibiotics in agricultural and clinical settings. The challenge is exacerbated by the lack of rapid surveillance for resistant bacteria in clinical, env...

  • Perspective
  • Open Access
4 Citations
2,201 Views
13 Pages

14 February 2025

This review attempts to summarize my three decades-long involvement in, and contribution to, the design, construction and testing of bioluminescent microbial sensor strains (bioreporters). With the understanding that such a document cannot be complet...

  • Article
  • Open Access
4 Citations
3,277 Views
18 Pages

14 February 2025

An effective and highly accurate strabismus screening method is expected to identify potential patients and provide timely treatment to prevent further deterioration, such as amblyopia and even permanent vision loss. To satisfy this need, this work s...

  • Communication
  • Open Access
1,275 Views
13 Pages

14 February 2025

A textile electrochemical sensor manufactured with commercially available textile materials is presented to determine glucose concentration. The sensor design consists of three electrodes manufactured with two different conductive yarns, one made wit...

  • Communication
  • Open Access
1 Citations
1,745 Views
14 Pages

Development of a Mass-Producible Microfluidic Device for Single and Bulk Mycobacteria Investigations

  • Adrian J. T. Teo,
  • Jianhui Gu,
  • Alexander Govyadinov,
  • Pavel Kornilovitch,
  • Peiyun Wang,
  • Serene Goh,
  • Nguyen Truong Tung,
  • Zhen Peng,
  • Keith Koh and
  • King Ho Holden Li

13 February 2025

We developed a mass-producible microfluidic device capable of long-term observations of single bacilli and bulk bacteria culture interactions for subsequent antimicrobial resistance (AMR) studies. The device provides high consistency across separate...

  • Review
  • Open Access
12 Citations
4,698 Views
24 Pages

Recent Advances in MXene-Based Electrochemical Sensors

  • Ziyi Zhao,
  • Jiayi Cao,
  • Boyu Zhu,
  • Xinru Li,
  • Lin Zhou and
  • Bin Su

13 February 2025

MXene is a new family of two-dimensional nanomaterials with outstanding electrical conductivity, tunable structure, biocompatibility, and a large surface area. Thanks to these unique physicochemical properties, MXene has been used for constructing el...

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Biosensors - ISSN 2079-6374