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Biosensors, Volume 15, Issue 1

January 2025 - 64 articles

Cover Story: Here, we present a novel electrochemical biosensor with a modified aptamer (C9t) for the detection of the spike (S) protein SARS-CoV-2 variants. Two aptamer modifications were employed: the removal of primer binding sites and the addition of two dithiol phosphoramidite anchor molecules. This reduced the fabrication time and increased the stability and sparsity of the receptor molecules. The performance of the biosensor was verified by electrochemistry, QCM-D, SPR, and XPS. Analyte-receptor binding was further confirmed by AFM-IR. The aptasensor has a low detection limit, high sensitivity, and a wide dynamic detection range with higher sensitivity for the Omicron compared to other variants. These results demonstrate the creation of a variant-selective refined C9t aptasensor that outperforms current rapid diagnostic tests. View this paper
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Articles (64)

  • Article
  • Open Access
1 Citations
2,030 Views
15 Pages

20 January 2025

Rapid, effective, and cost-effective methods for large-scale screening of pesticide residues in the environment and agricultural products are important for assessing potential environmental risks and safeguarding human health. Here, we constructed a...

  • Article
  • Open Access
16 Citations
2,552 Views
18 Pages

19 January 2025

The sensitive detection of inflammatory biomarkers in gingival crevicular fluid (GCF) is highly desirable for the evaluation of periodontal disease. Luminol-based electrochemiluminescence (ECL) immunosensors offer a promising approach for the fast an...

  • Systematic Review
  • Open Access
3 Citations
9,946 Views
18 Pages

19 January 2025

Timely ketone detection in patients with type 1 diabetes mellitus (T1DM) is critical for the effective management of diabetic ketoacidosis (DKA). This systematic review evaluates the current literature on breath-based analysis for ketone detection in...

  • Review
  • Open Access
16 Citations
3,460 Views
22 Pages

18 January 2025

The burgeoning field of biosensors has seen significant advancements with the induction of zinc oxide (ZnO) nanostructures, because of their unique structural, electrical, and optical properties. ZnO nanostructures provide numerous benefits for biose...

  • Article
  • Open Access
7 Citations
1,979 Views
17 Pages

17 January 2025

In the current work, the MWCNTs/ZnO nanocomposite was successfully synthesized using simple method. Then, FE-SEM, XRD, and EDX techniques were applied for morphological and structural characterization. Afterward, a sensitive voltammetric sensor based...

  • Article
  • Open Access
1 Citations
1,582 Views
15 Pages

Application of PS2M Aptamer as Receptor Layer for Electrochemical Detection of Lead Ions

  • Izabela Zaras,
  • Olga Kujawa,
  • Marcin Olszewski and
  • Marta Jarczewska

17 January 2025

Since lead can cause severe effects on living organisms’ health and life, the regular monitoring of Pb levels in water and soil is of particular significance. Recently, it was shown that lead ions can also be detected using affinity-based biose...

  • Article
  • Open Access
2,308 Views
11 Pages

Rapid Detection of microRNA-122 in Serum and Finger Blood Using a Lateral Flow Nucleic Acid Biosensor

  • Min Zhang,
  • Meijing Ma,
  • Jiahui Wang,
  • Yurui Zhou,
  • Xueji Zhang and
  • Guodong Liu

17 January 2025

MicroRNA122 (miR-122) is a microRNA that is highly expressed in hepatocytes and has been identified as a prospective therapeutic target and biomarker for liver injury. An expanding body of research has demonstrated that miR-122 is a critical regulato...

  • Review
  • Open Access
12 Citations
2,947 Views
20 Pages

Electrochemical Biosensors 3D Printed by Fused Deposition Modeling: Actualities, Trends, and Challenges

  • Luiz Ricardo Guterres Silva,
  • Carlos Eduardo Costa Lopes,
  • Auro Atsushi Tanaka,
  • Luiza Maria Ferreira Dantas,
  • Iranaldo Santos Silva and
  • Jéssica Santos Stefano

17 January 2025

The technology of 3D printing, particularly fused deposition modeling (FDM) 3D printing, has revolutionized the development of electrochemical biosensors, offering a versatile and cost-effective approach for clinical applications. This review explore...

  • Article
  • Open Access
1 Citations
1,656 Views
19 Pages

16 January 2025

Colorectal cancer represents 10% of all the annual tumors diagnosed worldwide, being often not timely diagnosed, because its symptoms are typically lacking or very mild. Therefore, it is crucial to develop and validate innovative low-invasive techniq...

  • Article
  • Open Access
4 Citations
2,028 Views
14 Pages

Basic Characteristics of Ionic Liquid-Gated Graphene FET Sensors for Nitrogen Cycle Monitoring in Agricultural Soil

  • Naoki Shiraishi,
  • Jian Lu,
  • Fatin Bazilah Fauzi,
  • Ryo Imaizumi,
  • Toyohiro Tsukahara,
  • Satoshi Mogari,
  • Shosuke Iida,
  • Yusuke Matsukura,
  • Satoshi Teramoto and
  • Keisuke Yokoi
  • + 2 authors

16 January 2025

Nitrogen-based fertilizers are crucial in agriculture for maintaining soil health and increasing crop yields. Soil microorganisms transform nitrogen from fertilizers into NO3−–N, which is absorbed by crops. However, some nitrogen is conve...

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Biosensors - ISSN 2079-6374