Design, Fabrication, and Applications of Microfluidic Devices for Biosensing

Dear Colleagues,

The main topic of this Special Issue is the design, fabrication, and applications of microfluidic devices for biosensing, and we aim to gather original articles and reviews showing research advances, fabrication, innovative applications, new challenges, and future perspectives in microfluidic devices for biosensing in biology, medicine, health, environmental monitoring, and more.

Microfluidic technology enables the automated pretreatment of samples, as well as the transportation of nanoliters or picoliters of solutions to designated biosensing sites. This facilitates high-throughput and automated detection in biosensors. Furthermore, the characteristics of microfluidics, such as the large specific surface area, can enhance the sensitivity of biosensors. Consequently, numerous biosensors incorporating microfluidic structures have been developed.

The objective of this Special Issue is to provide readers with an understanding of the potential of microfluidic technology in the development of biosensors, as well as an overview of the current challenges and opportunities in meeting application needs. The authors may include the fabrication processes for microfluidic devices. Indeed, the most conventional methods, e.g., PDMS on glass or SiO₂, though successful in a laboratory setting, are not applicable on an industrial basis, which makes them very limited. Thus, reviews of alternative processes would be very interesting for readers.

Submissions may include, but are not limited to, the following topics:

• sample-in–result-out  bioassay devices/point-of-care devices/diagnostic devices/healthcare medical devices;
• devices for high-throughput, low-cost, and robust bioassays;
• organ-on-a-chip models;
• macro–micro interfaces for multiscale fluid handling, integration into experimental workflows, and coupling to analytical instruments;
• reviews of fabrication processes that are more suitable for industrial production than conventional methods, e.g., PDMS on glass or SiO₂;
• microfluidic biosensing principles and devices for increased sensitivity.

Dr. Lei Wu
Dr. Xiang Qian
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• microfluidic
• biosensors
• high-throughput
• automation