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Biosensors, Volume 15, Issue 3

March 2025 - 72 articles

Cover Story: The advancement of personalized medicine and digital health has significantly accelerated the development of wearable and implantable biosensors. However, the effective use of these sensors is often limited by issues such as biofouling and foreign body responses, which can severely impact sensor performance and longevity. In this featured paper, the authors present a novel nanocomposite coating made from cross-linked bovine serum albumin, pentaamine-functionalized reduced graphene, and covalently bound antibiotics, which prevents non-specific protein, microbial, and fibroblast attachment while remaining non-toxic to primary human cells. This nanocomposite coating has the potential to greatly improve the longevity and clinical translatability of implantable biosensors, enabling continuous monitoring of multiple diseases and real-time therapeutic responses. View this paper
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Articles (72)

  • Review
  • Open Access
2 Citations
2,197 Views
26 Pages

20 March 2025

Viral infectious diseases pose a serious threat to global public health due to their high transmissibility, rapid mutation rates, and limited treatment options. Recent outbreaks of diseases such as plague, monkeypox, avian influenza, and coronavirus...

  • Review
  • Open Access
8 Citations
4,293 Views
19 Pages

20 March 2025

This article explores the development and application of innovative piezoelectric sensors in point-of-care diagnostics. It highlights the significance of bedside tests, such as lateral flow and electrochemical tests, in providing rapid and accurate r...

  • Article
  • Open Access
2 Citations
1,056 Views
18 Pages

19 March 2025

Diabetes mellitus is a pathological condition that requires continuous measurement of glucose concentration in human blood. In this study, two enzymatic mediator-free glucose biosensors based on premodified graphite rod (GR) electrodes were developed...

  • Article
  • Open Access
1,025 Views
17 Pages

Magnetically Localized Detection of Amplified DNA Using Biotinylated and Fluorescent Primers and Magnetic Nanoparticles

  • Etienne Orsini,
  • Franz Bruckert,
  • Marianne Weidenhaupt,
  • Orphée Cugat,
  • Paul Kauffmann and
  • Sarah Delshadi

18 March 2025

Quantitative nucleic acid detection is widely used in molecular diagnostics for infectious diseases. Here, we demonstrate that the previously developed MLFIA (magnetically localized fluorescent immunoassay) has the potential to detect Polymerase Chai...

  • Review
  • Open Access
3 Citations
3,363 Views
54 Pages

18 March 2025

Peritoneal dialysis (PD) is a vital treatment for end-stage renal disease patients, but its efficacy is often compromised by complications such as infections and peritoneal fibrosis. Biological field-effect transistors (BioFETs) present a promising s...

  • Article
  • Open Access
8 Citations
7,745 Views
15 Pages

A Wearable Molecularly Imprinted Electrochemical Sensor for Cortisol Stable Monitoring in Sweat

  • Yitao Chen,
  • Zidong He,
  • Yuanzhao Wu,
  • Xinyu Bai,
  • Yuancheng Li,
  • Weiwei Yang,
  • Yiwei Liu and
  • Run-Wei Li

18 March 2025

Cortisol, a steroid hormone, is closely associated with human mental stress. The rapid, real-time, and continuous detection of cortisol using wearable devices offers a promising approach for individual mental health. These devices must exhibit high s...

  • Article
  • Open Access
4 Citations
1,306 Views
17 Pages

A Portable Smartphone-Based 3D-Printed Biosensing Platform for Kidney Function Biomarker Quantification

  • Sangeeta Palekar,
  • Sharayu Kalambe,
  • Jayu Kalambe,
  • Madhusudan B. Kulkarni and
  • Manish Bhaiyya

18 March 2025

Detecting kidney function biomarkers is critical for the early diagnosis of kidney diseases and monitoring treatment efficacy. In this work, a portable, 3D-printed colorimetric sensor platform was developed to detect key kidney biomarkers: uric acid,...

  • Review
  • Open Access
1 Citations
4,283 Views
37 Pages

17 March 2025

Cardiovascular diseases have long been a major challenge to human health, and the treatment differences caused by individual variability remain unresolved. In recent years, personalized cardiovascular drug therapy has attracted widespread attention....

  • Article
  • Open Access
2,637 Views
16 Pages

16 March 2025

The Glucose Management Indicator (GMI) is a biomarker of glycemic control which estimates hemoglobin A1c (HbA1c) based on the average glycemia recorded by continuous glucose monitoring sensors (CGMS). The GMI provides an immediate overview of the pat...

  • Review
  • Open Access
14 Citations
9,324 Views
43 Pages

Biosensor Technologies for Water Quality: Detection of Emerging Contaminants and Pathogens

  • Antía Fdez-Sanromán,
  • Nuria Bernárdez-Rodas,
  • Emilio Rosales,
  • Marta Pazos,
  • Elisa González-Romero and
  • Maria Ángeles Sanromán

15 March 2025

This review explores the development, technological foundations, and applications of biosensor technologies across various fields, such as medicine for disease diagnosis and monitoring, and the food industry. However, the primary focus is on their us...

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Biosensors - ISSN 2079-6374Creative Common CC BY license